Sodium chloride (nacl)

Manufactured by SD Fine Chemicals

Sourced in India

Sodium chloride is a chemical compound with the formula NaCl, commonly known as table salt or rock salt. It is a crystalline solid that is colorless or white in appearance. Sodium chloride is a vital mineral that plays a fundamental role in regulating fluid balance and nerve function in the human body.

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15 protocols using sodium chloride (nacl)

Graphite-Reinforced PEEK Composite Synthesis

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Poly(ether ether ketone)
(PEEK) (medium melt viscosity grade 450 PF) was obtained from Victrex
PLC, England, and 3-aminopropyl trimethoxysilane (99%) was received
from Sigma-Aldrich Chemicals. Graphite (Gt) powder (size 100 μm),
dimethylacetamide (DMAc), phosphoric acid, formaldehyde, acetone,
methanol, H₂SO₄, NaOH, NaCl, NaNO₃, KMnO₄, H₂O₂, HCl, and Na₂SO₄ of analytical grade were obtained from SD Fine Chemicals,
India and used with proper purification. All experiments were performed
using ultrapure water (resistivity: 18.2 MΩ cm).

Das A.K., Manohar M, & Shahi V.K. (2018). Cation-Exchange Membrane with Low Frictional Coefficient and High Limiting Current Density for Energy-Efficient Water Desalination. ACS Omega, 3(8), 10331-10340.

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Formulation and Evaluation of Atenolol

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Atenolol was gift sample from Smruthi Organics Pvt. Ltd., Hyderabad, India. NaCl, mannitol, dicalcium phosphate, magnesium stearate, talc, hydrochloric acid, and sodium hydroxide were purchased from S.D. Fine Chemicals, Mumbai, India. PVP k-30 was purchased from Himedia Laboratories Ltd., Mumbai, India. Cellulose acetate (CA) was a gift sample from AET Pharma, Hyderabad, India. Ethyl cellulose, HPMC K₄M, and dibutyl phthalate (DBP) were gift samples from Dr. Reddy's Laboratories, Hyderabad, India. Acetone, isopropyl alcohol, and poly (ethylene glycol) (PEG)-400 were purchased from Merck Ltd., Hyderabad, India. All chemicals and reagents used were of analytical or pharmacopoeial grade.

Arjun N., Narendar D., Sunitha K., Harika K, & Nagaraj B. (2016). Development, evaluation, and influence of formulation and process variables on in vitro performance of oral elementary osmotic device of atenolol. International Journal of Pharmaceutical Investigation, 6(4), 238-246.

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Formulation and Evaluation of Metformin Extended-Release Tablets

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Metformin hydrochloride was obtained as a gift sample from Sun Pharma, Gurugram, India. Hydroxy propyl cellulose (HPC) Type H, Eudragit L-100, and Eudragit S-100 from Jubilant Generics Limited, Noida, India; sodium hydroxide, m ethanol (high-performance liquid chromatography [HPLC] Grade), and ethanol (95%) from Merck India, Mumbai, India; sodium chloride, triethyl citrate, and ethyl cellulose from S.D. Fine Chemicals, New Delhi, India. All the chemicals used in this study were of analytical grade.

Pandey R, & Selvamurthy W. (2020). Design and in vitro characterization of novel pulsatile delivery system of biguanide antidiabetic drug. Journal of Pharmacy & Bioallied Sciences, 12(3), 356-368.

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Development and Evaluation of Cholesterol Nanodispersion

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Unicure Pvt. Limited (Noida, India) provided CIP. The cholesterol (CHO), Span 60, and sodium deoxycholate (SDC) were procured from SD Fine Chemicals (Mumbai, India). Acetonitrile, chloroform, methanol, and dialysis bag (MWCO 12kDa) were procured from Sigma Aldrich (Bengaluru, India). Carbopol 934P, Hydroxy propyl methyl cellulose K100 M (HPMC-K100M), Sodium Hydroxide (NaOH), Calcium chloride (CaCl₂), Sodium Bicarbonate (NaHCO₃), and Sodium Chloride (NaCl) were procured from SD fine Chem Limited (Mumbai, Maharashtra, India). Fluid thioglycolate and soya bean casein digest media were obtained from HiMedia (Mumbai, India). The other chemicals utilized in this research are analytical grade.

Alsaidan O.A., Zafar A., Yasir M., Alzarea S.I., Alqinyah M, & Khalid M. (2022). Development of Ciprofloxacin-Loaded Bilosomes In-Situ Gel for Ocular Delivery: Optimization, In-Vitro Characterization, Ex-Vivo Permeation, and Antimicrobial Study. Gels, 8(11), 687.

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Synthesis of Transfluthrin-loaded PCL Nanoparticles

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Neem oil, phthalic anhydride, and sodium chloride were purchased from SD Fine Chemicals, India. Sodium methoxide was from Spectrochem Pvt. Ltd., Mumbai, India. Xylene and diethyl ether were from Thomas Baker (Chemicals) Pvt. Ltd., Mumbai, India. Polycaprolactone (PCL), diethanolamine, deuterated chloroform (CDCl₃), chloroform were procured from Sigma Aldrich Chemicals, Mumbai, India. Sodium sulphate and sodium bicarbonate were purchased from Merck Ltd, Mumbai, India. Transfluthrin was obtained as a gift sample from the Entomology Division, CSIR-National Chemical Laboratory. All other chemicals and reagents were of analytical grade.

Konchada S., Killi N., Sayyad S., Gathalkar G.B, & Gundloori R.V. (2020). Blends of neem oil based polyesteramide as nanofiber mats to control Culicidae. RSC Advances, 10(70), 42827-42837.

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Formulation and Evaluation of Pilocarpine HCl Topical Gel

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The pilocarpine HCl was kindly received as a gift sample by M/s Zydus Cadila Health Care Ltd. (Ahmedabad, India). Sorbitan monolaurate (span 20), sorbitan monosterate (span 60), sorbitan monooleate (span 80), cholesterol, locust bean gum and carbopol 934 were procured from Loba Chemie Pvt. Ltd. (Mumbai, India). Isopropanol, methanol, acetone, chloroform, boric acid, sodium hydroxide, sodium bicarbonate, potassium chloride, glacial acetic acid, magnesium, sodium chloride, calcium chloride dehydrate, potassium dihydrogen phosphate and disodium hydrogen phosphate were purchased from were purchased from S.D Fine chemicals (Mumbai, India). Double distilled water was used throughout the study.

Jain N., Verma A, & Jain N. (2020). Formulation and investigation of pilocarpine hydrochloride niosomal gels for the treatment of glaucoma: intraocular pressure measurement in white albino rabbits. Drug Delivery, 27(1), 888-899.

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Spectroscopic Characterization of Donor-Acceptor Complex

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The donor 2-methyl-8-quinolinol (2 MQ), acceptor chloranilic acid (CHLA), and CT-DNA were acquired from Sigma-Aldrich USA (98%). Sodium chloride and tris buffer (99.5%) were procured from SD Fine Chemicals Limited. The solvents acetonitrile (Finar 99.5%), methanol (Finar 99.5%), and ethanol (Hayman 100%) were used at a high analytical grade. Safety glasses, hand covers, and dust masks were used during all experiments.

Manojkumar P., H.a.r.i.l.a.l., Mahipal V., Suresh G., Venkatesh N., Ramesh M, & Parthasarathy T. (2021). Exploring the charge transfer dynamics of hydrogen bonded crystals of 2-methyl-8-quinolinol and chloranilic acid: synthesis, spectrophotometric, single-crystal, DFT/PCM analysis, antimicrobial, and DNA binding studies. RSC Advances, 11(63), 39994-40010.

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Synthesis of Silver Nanoparticles

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Acetone, ethylene glycol, silver nitrate, ammonium solution, potassium chloride, polyvinylpyrrolidone (K 90), dichloromethane, sodium chloride, and sodium borohydride were purchased from SD Fine Chemicals Ltd., Mumbai, India. All the chemicals of analytical grade were used without any further purification. The deionized water (18 MΩ) used in the experiments was obtained from Elga Pure lab Q7/15 water purifier Woodridge, IL, USA.

Potdar R.P., Khollam Y.B., Shaikh S.F., More P.S, & Rana A.U. (2022). Polyvinylpyrrolidone-Capped Silver Nanoparticles for Highly Sensitive and Selective Optical Fiber-Based Ammonium Sensor. Nanomaterials, 12(19), 3373.

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Physicochemical Characterization of Acridone Derivatives

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Characterization of acridone derivatives AC2, AC7, and AC26 were carried out by using all the chemicals of analytical grade. Hydrochloric acid and sodium hydroxide were procured from Sisco Research Lab Pvt. Ltd (Mumbai, India). Potassium dihydrogen orthophosphate, methanol and ortho-phosphoric acid (85% pure) was received from Loba Chemie Pvt. Ltd. (Mumbai, India). Sodium chloride was received from SD Fine-Chem Limited (Mumbai, India). Milli-pore water was used throughout the study. Chemical information like the molecular weight of compounds was determined by obtaining ESI-MS spectroscopy using methanol as solvent. pH calculated by using pH analyzer (Lab India) and PKa determined by using UV-Vis spectrophotometer (Shimadzu, Japan). Melting point was calculated by Digital Melting point apparatus (Veego India). Lipophilicity was determined by using software like Chem Draw 15 and ALGOPS 2.1 (16 (link)). In order to determine the Blood Brain Barrier (BBB) permeability of the compounds, we have used Online BBB Predictor (https://www.cbligand.org/BBB/predictor.php) using SVM Machine Learning algorithm and PubChem as the fingerprint (17 (link)).

Chakravarty M., Ganguli P., Murahari M., Sarkar R.R., Peters G.J, & Mayur Y.C. (2021). Study of Combinatorial Drug Synergy of Novel Acridone Derivatives With Temozolomide Using in-silico and in-vitro Methods in the Treatment of Drug-Resistant Glioma. Frontiers in Oncology, 11, 625899.

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Reagent Preparation for Analytical Assays

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All the chemicals and reagents used in the experiments were of analytical grade (AR). Potassium dihydrogen phosphate and sodium di hydrogen phosphate were purchased from Sigma-Aldrich Company, Mumbai. Sodium carbonate, potassium chloride was obtained from RFCL Limited, New Delhi. Sodium hydroxide, Sodium potassium tartarate, copper sulphate and sodium chloride were supplied by SD Fine-Chem Limited, Mumbai. Folin-ciocalteu was obtained from Merck Life Science Private Limited, Mumbai.

Sarkar S., Mondal M., Ghosh P., Saha M., & Chatterjee S. (2020). Quantification of total protein content from some traditionally used edible plant leaves: A comparative study. Journal of Medicinal Plants Studies, 8(4), 166-170.

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