Trio 3.0 tesla mri scanner

The MR images were acquired with a Siemens Trio 3.0 Tesla MRI scanner (Siemens, Erlangen, Germany) at the Shanghai Key Laboratory of Magnetic Resonance, East China Normal University. All patients were asked to discontinue their pain medications 1–3 days before fMRI. Before fMRI, the participant’s head was stabilized using foam pads to minimize both head movement and scanner noise. Resting-state fMRI of the whole brain was performed using an echo-planar imaging (EPI) sequence: axial slice: 33, slice thickness: 4 mm, no gap, matrix: 64 × 64, repetition time: 2,000 ms, echo time: 30 ms, flip angle = 90°, and field of view: 192 mm × 192 mm. During the fMRI scanning, all subjects were instructed to keep their eyes closed, relax, and movements as little as possible without thinking about anything in particular. Each scan lasted for 8 minutes and 6 seconds, but the first six seconds would comprise of dummy scanning. Thus, a total of 240 image volumes were collected. Additionally, T1-weighted sagittal images covering the entire brain were obtained with a magnetization-prepared rapid gradient echo sequence: slices per slab: 192, slice thickness: 0.9 mm, gap: 0.45 mm, repetition time: 2530 ms, echo time: 2.4 ms, inversion time: 1100 ms, field of view: 256 mm × 256 mm, flip angle: 7°, and matrix: 256 × 256.

All data were acquired using a Siemens Trio 3.0 Tesla MRI scanner (Siemens, Erlangen, Germany) at the Shanghai Key Laboratory of Magnetic Resonance, East China Normal University. We used foam pads to fix the head of each participant to reduce both head movements and scanner noise. Resting-state functional images were acquired using an echo-planar imaging (EPI) sequence (30 transverse slices, slice thickness/gap = 4 mm/0.8 mm, matrix = 64×64, repetition time = 2000 ms, echo time = 30 ms, flip angle = 90°, field of view = 220 mm×220 mm). Structural images of T1-weighted anatomical images in a sagittal orientation were obtained using magnetization prepared by rapid gradient echo sequence (MPRAGE) (192 slices covered the whole brain, slice thickness/gap = 1 mm/0.5 mm, repetition time = 1900 ms, echo time = 3.42 ms, field of view = 240 mm×240 mm, matrix = 256×256). To identify the location of the lesion, T2-weighted images were collected using a turbo-spin-echo sequence (30 axial slices, thickness = 5 mm, no gap, repetition time = 6000 ms, echo time = 93 ms, field of view = 220 mm×220 mm, matrix = 320×320). During the resting-state functional MRI collection, the participants were instructed to close their eyes but to remain awake while trying not to think about anything specific. We collected a total of 240 image volumes.

All images were acquired using a Siemens Trio 3.0 Tesla MRI scanner (Siemens, Erlangen, Germany). Tight but comfortable foam padding was used to minimize head motion, and earplugs were used to reduce scanner noise. Functional MR images were collected using an echo-planar imaging (EPI) sequence with the following scan parameters: repetition time (TR)/echo time (TE) = 2000/30 ms; field of view (FOV) = 220 mm×220 mm; matrix = 64×64; flip angle (FA) = 90°; slice thickness = 3 mm; gap = 1 mm; 32 interleaved transversal slices; and 180 volumes. During the fMRI scans, all subjects were instructed to keep their eyes closed, stay as motionless as possible, think of nothing in particular, and not fall asleep. Structural images were obtained in the sagittal orientation by employing a magnetization prepared rapid gradient echo sequence over the whole brain: 176 slices, thickness/gap = 1.0/0 mm, matrix = 256×224, TR = 1600 ms, TE = 2.6 ms, FA = 9°, and FOV = 256 mm×224 mm. T2-weighted images were acquired using a turbo-spin-echo sequence: 20 axial slices, thickness/gap = 5.0/6.5 mm, matrix = 512×416, TR = 4140 ms, TE = 92 ms, and FOV = 187 mm×230 mm.

Images were obtained using a Siemens Trio 3.0 Tesla MRI scanner (Siemens, Erlangen, Germany) with a standard 12-channel head coil. Restraining foam pads was used to reduce head motion and earplugs were used to reduce scanner noise. High-resolution T1-weighted anatomical images (repetition time (TR) = 1900 ms, echo time (TE) = 2.46 ms, flip angle = 9 degrees, 32 transverse slices, field of view (FOV) = 240 × 240 mm, matrix = 256 × 256, slice thickness = 1 mm) were acquired using a magnetization prepared rapid gradient-echo sequence. Resting-state functional MRI data were acquired using a single-shot, gradient-recalled echo planar imaging sequence (TR = 2000 ms, TE = 25 ms, flip angle = 90 degrees). 32 transverse slices (FOV = 240 × 240 mm, matrix = 64 × 64, slice thickness = 5 mm) resulting in a total of 80/157 volumes and a scan time of 164/314 s, respectively, in eyes-open and eyes-closed rs-fMRI. During the scan, participants were instructed to stay aware. After the scan, the technicians would check the quality of structural images. If any abnormalities were found in the images, participants were re-scanned.

The following MRI scans were performed on a Trio 3.0 Tesla MRI scanner (Siemens, Erlangen, Germany): 1) rs-fMRI with repetition time (TR)/echo time (TE) = 2000/30 ms, field of view (FOV) = 200 × 200 mm², matrix = 64 × 64, 30 interleaved axial slices with thickness = 4 mm and inter-slice gap = 1.2 mm. 240 time points were acquired; 2) High resolution anatomical scan using a three dimensional magnetization prepared rapid gradient echo (MPRAGE) sequence with the following parameters: TR/TE = 1900/2.26 ms; matrix = 240 × 256 × 176; FOV = 215 × 230 × 176 mm³; 3) Diffusion tensor imaging (DTI) with TR/TE = 7200/104 ms; matrix = 128 × 128; FOV = 230 × 230 mm²; 49 axial slices (thickness = 2.5 mm); 64 nonlinear gradient directions (b = 0, 1000 s/mm²); 4) Two dimensional structural MRI with a T2-weighted sequence with TR/TE = 5100/117 ms; matrix = 416×416; FOV = 240×240 mm²; number of excitations = 3; 22 axial slice with a thickness of 6.5 mm.