Medspec

Manufactured by Bruker

Sourced in Germany

The Medspec is a laboratory equipment product developed by Bruker. It is designed to provide reliable and accurate measurements for scientific research and analysis. The core function of the Medspec is to perform spectroscopic analysis of samples, enabling researchers to identify and quantify the composition of materials. The product specifications and technical details are available upon request.

Automatically generated - may contain errors

Lab products found in correlation

Trio console, by Siemens (1 mentions)

Close spelling variants of this product

MedSpec S300 (5 citations) BioSpin MedSpec 4-T scanner (5 citations) MedSpec system (4 citations) Medspec MRI scanner (4 citations) MEDSPEC 30/80 AVANCE imager (3 citations) MEDSPEC 30/80 AVANCE (3 citations) MedSpec Biospin (3 citations) MedSpec Biospin MR scanner (3 citations) MedSpec 4-T head scanner (3 citations) MedSpec 4T scanner (3 citations)

13 protocols using medspec

Functional Neuroimaging of Early Parkinson's

Check if the same lab product or an alternative is used in the 5 most similar protocols

The 18 early stage PD patients, and 16 age matched volunteers were scanned at the Wolfson Brain Imaging Centre using a 3 T Bruker Medspec scanner (Bruker s300, Ettingen, Germany) with 21 slices (4 mm slices with 1 mm inter-slice gap) per image and a TR of 1.1 sec and in plane resolution of 3.125 × 3.125 mm 850 T2-weighted echo-planar images, depicting BOLD contrast were acquired per run, and the first 18 were discarded to avoid T1 equilibrium effects. Images were slice time acquisition corrected, reoriented, subject motion corrected, geometrically undistorted using phase maps (Cusack, Brett, & Osswald, 2003 (link)), spatially normalised to the standard Montreal Neurological Institute EPI template, smoothed with an 8 mm full-width at half-maximum Gaussian kernel, and modelled using SPM (Wellcome Department of Cognitive Neurology).

Gruszka A., Hampshire A., Barker R.A, & Owen A.M. (2017). Normal aging and Parkinson's disease are associated with the functional decline of distinct frontal-striatal circuits. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior, 93, 178-192.

+ Open protocol

+ Expand

Resting-State fMRI Acquisition and Preprocessing

Check if the same lab product or an alternative is used in the 5 most similar protocols

The images were acquired on a 4 Tesla Bruker Medspec whole-body scanner in Brisbane, Australia. RS-fMRI was performed with a repetition time TR=2100 ms, echo time TE=30 ms, flip angle=90°, field of view FOV=230 mm, and total acquisition length of 5 min:19 s. Thirty-six 3 mm-thick transverse slices, with 0.6 mm gap, were acquired per volume, yielding a voxel size of 3.6×3.6×3.0 mm. In total, 150 volumes were collected, with the first 5 volumes discarded from the analysis to allow time for steady state to occur. During the scan participants were asked to close their eyes, empty their minds, and to try not to fall asleep. Participants who reported having fallen asleep were excluded, to ensure a consistent experimental procedure. The RS scan was part of a larger protocol lasting approximately 60 minutes, including a 3D T1-weighted scan to which the functional scans were coregistered. Structural scans were acquired with TR=1500 ms, TE=3.35 ms, TI=700 ms, flip angle=8°, 256 or 240 (coronal or sagittal) slices, FOV=240 mm, 256 × 256 × 256 (or 256 × 256 × 240) matrix, slice thickness=0.9 mm and voxel size 0.9 mm³.

Couvy-Duchesne B., Blokland G.A., Hickie I.B., Thompson P.M., Martin N.G., de Zubicaray G.I., McMahon K.L, & Wright M.J. (2014). Heritability of head motion during resting state functional MRI in 462 healthy twins. NeuroImage, 102(0 2), 424-434.

+ Open protocol

+ Expand

Multimodal Neuroimaging of Neurodegenerative Diseases

Check if the same lab product or an alternative is used in the 5 most similar protocols

MRI was performed at the Center for Imaging of Neurodegenerative
Diseases of the San Francisco Veterans Administration Medical Center using a 4T
Siemens/ Bruker MedSpec whole-body scanner equipped with a Siemens TRIO console
(Siemens AG, Erlangen, Germany) and a product transmit/receive 8-channel head
coil. A T1-weighted three-dimensional magnetization-prepared rapid acquisition
gradient echo (MPRAGE, TR/T1/TE = 2300/950/3 ms, voxel size = 1.0 × 1.0
× 1.0 mm³, flip angle 7°, bandwidth = 200Hz/ pixel)
was acquired. Four consecutive DTI scans were acquired for each participant to
increase signal-to-noise (TR/TE = 6000/77 ms, 2.0 × 2.0 × 3.0
mm³ voxels, flip angle 90°, six directions, b-values = 0
and 800s/mm² ).

Wright P.W., Vaida F.F., Fernández-de Thomas R.J., Rutlin J., Price R.W., Lee E., Peterson J., Fuchs D., Shimony J.S., Robertson K.R., Walter R., Meyerhoff D.J., Spudich S, & Ances B.M. (2015). Cerebral white matter integrity during primary HIV infection. AIDS (London, England), 29(4), 433-442.

+ Open protocol

+ Expand

Resting-State fMRI Acquisition Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

Images were acquired on a 4 T Bruker Medspec whole-body scanner. For rs-fMRI scans, all subjects were instructed to lie still in the scanner, relax with their eyes closed and think of nothing in particular. All participants included confirmed that they remained awake and alert through the scanning session. The rs-fMRI scans lasted 5 min 19 sec with a total of 150 volumes, with the following parameters: repetition time (TR)=2100 ms, echo time (TE)=30 ms, flip angle (FA)=90°, field of view (FOV)=230 mm, 36 transverse 3 mmthick slices with 0.6 mm gap, yielding a voxel size of 3.6×3.6×3.0 mm³. High-resolution T1W images were acquired with an inversion recovery rapid gradient echo sequence (TR/TE/TI = 1500/3.35/700 ms, FA=8°, FOV=240 mm, 256×256 acquisition matrix, 0.9×0.9×0.9 mm³ voxels/0 mm gap).

Wang J., Braskie M.N., Hafzalla G.W., Faskowitz J., McMahon K.L., de Zubicaray G.I., Wright M.J., Yu C, & Thompson P.M. (2016). Relationship of a common OXTR gene variant to brain structure and default mode network function in healthy humans. NeuroImage, 147, 500-506.

+ Open protocol

+ Expand

High-Resolution Structural MRI Analysis

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

High-resolution structural MRI scans were obtained on a single 4-Tesla scanner (Bruker Medspec) using the same imaging protocol. Three-dimensional T1-weighted images were acquired with an inversion recovery rapid gradient echo sequence (TI/TR/TE = 700/1500/3.35 ms; flip angle = 8°; slice thickness = 0.9 mm). MR Images were processed using FreeSurfer (http://surf.nmr.mgh.harvard.edu/) [11 (link), 16 (link)–18 (link)]. Quality control of image segmentation was performed according to the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium procedures (http://enigma.ini.usc.edu/protocols/imaging-protocols) [52 (link)].

Silvennoinen K., Gawel K., Tsortouktzidis D., Pitsch J., Alhusaini S., van Loo K.M., Picardo R., Michalak Z., Pagni S., Martins Custodio H., Mills J., Whelan C.D., de Zubicaray G.I., McMahon K.L., van der Ent W., Kirstein-Smardzewska K.J., Tiraboschi E., Mudge J.M., Frankish A., Thom M., Wright M.J., Thompson P.M., Schoch S., Becker A.J., Esguerra C.V, & Sisodiya S.M. (2022). SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility. Acta Neuropathologica, 144(1), 107-127.

+ Open protocol

+ Expand

High-Resolution 3D Brain Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

3-Dimensional T1-weighted images were acquired on a 4 T Bruker Medspec scanner using an inversion recovery rapid gradient echo protocol. Key acquisition parameters were: TI = 700 ms, TR = 1500 ms, TE = 3.35 ms, voxel size 0.94 × 0.98 × 0.98 mm, flip angle = 8°, slice thickness = 0.9 mm, 256 × 256 acquisition matrix.

Whelan C.D., Hibar D.P., van Velzen L.S., Zannas A.S., Carrillo-Roa T., McMahon K., Prasad G., Kelly S., Faskowitz J., deZubiracay G., Iglesias J.E., van Erp T.G., Frodl T., Martin N.G., Wright M.J., Jahanshad N., Schmaal L., Sämann P.G, & Thompson P.M. (2015). Heritability and reliability of automatically segmented human hippocampal formation subregions. NeuroImage, 128, 125-137.

+ Open protocol

+ Expand

Resting-state fMRI with Structural Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

Imaging was conducted on a 4 Tesla Bruker Medspec whole body scanner (Bruker). Participants were instructed to remain at rest with their eyes closed, and to not think of anything in particular and not fall asleep. The imaging sequence was a T2*-weighted gradient echo, echo planar imaging (GE-EPI) sequence (repetition time TR = 2100 ms; echo time TE = 30 ms; flip angle = 90°; field of view FOV = 230 mm × 230 mm, pixel size 3.6×3.6mm, 36 coronal 3.0mm slices with 0.6mm gap, 150 volumes, total scan time 315s). Prior to the rs-fMRI scan a T1-weighted 3D structural image was acquired (MPRAGE, TR = 1500 ms; TE = 3.35 ms; inversion time TI=700ms; flip angle = 8°; FOV = 230 mm³, pixel size 0.9×0.9×0.9mm).

Sinclair B., Hansell N.K., Blokland G.A., Martin N.G., Thompson P.M., Breakspear M., de Zubicaray G.I., Wright M.J, & McMahon K.L. (2015). Heritability of the Network Architecture of Intrinsic Brain Functional Connectivity. NeuroImage, 121, 243-252.

+ Open protocol

+ Expand

MRI Imaging Protocol for Neutral Joint Positioning

Check if the same lab product or an alternative is used in the 5 most similar protocols

For imaging, the specimen was secured to a non-magnetic holder designed to keep the joint in a neutral state while also preventing any relative movement of the joint. Magnetic resonance (MR) images were acquired at the University Hospitals & Case Western Reserve University, Cleveland, OH, using a 4 Tesla scanner (Medspec, Bruker Biospin Corp., Billerica, MA) and the following imaging protocol: T1 Turbo Spin Echo, without fat suppression, having an in-plane resolution of 0.3125 mm, and 1.5 mm slice thickness. Image sets were obtained in all three orthogonal planes (coronal,axial and sagittal) using the same protocol. In addition to the various tissues of interest, the imaging protocol also allowed clear delineation of registration markers for future digitization from the MR images in order to establish the relationship between mechanical testing and imaging coordinate systems.

Chokhandre S., Colbrunn R., Bennetts C, & Erdemir A. (2015). A Comprehensive Specimen-Specific Multiscale Data Set for Anatomical and Mechanical Characterization of the Tibiofemoral Joint. PLoS ONE, 10(9), e0138226.

+ Open protocol

+ Expand

Whole-Brain 3D T1-Weighted MRI Acquisition

Check if the same lab product or an alternative is used in the 5 most similar protocols

T1‐weighted (T1w) 3D whole‐brain images (T1/TR/TE = 700/1500/3.35 ms; FA = 8°, voxel size = 0.94 × 0.94 × 0.90 mm) were acquired for each participant on a 4 T Bruker Medspec whole‐body MRI system paired with a transverse electromagnetic head coil.

Strike L.T., Kerestes R., McMahon K.L., de Zubicaray G.I., Harding I.H, & Medland S.E. (2024). Heritability of cerebellar subregion volumes in adolescent and young adult twins. Human Brain Mapping, 45(8), e26717.

+ Open protocol

+ Expand

High-Resolution Multimodal Brain Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

The T1-weighted and diffusion-weighted images were acquired on a 4T Bruker Medspec whole-body scanner (Bruker Medical, Ettingen, Germany). Three-dimensional T1-weighted images were acquired with a magnetization-prepared rapid gradient echo (MPRAGE) sequence to resolve anatomy at high resolution. Acquisition parameters were: inversion time (TI)/repetition time (TR)/echo time (TE)=700/1500/3.35ms, flip angle = 8°, slice thickness = 0.9 mm with a 256 × 256 × 256 acquisition matrix. Diffusion images were acquired using a commercial single shot echo planar multi-direction diffusion weighted sequence, employing a dual bipolar diffusion gradient and a double spin echo. The imaging parameters were: 55 axial slices; 2 mm slice thickness; field of view 23 cm × 23 cm; TR/TE 150/92.3 ms; acquisition matrix 128 × 128, resulting in an in-plane resolution of 1.80 × 1.80 mm. Ninety four diffusion-weighted images were acquired at b = 1159 s/mm², in which the encoding gradients were distributed in space using the electrostatic approach [Jones et al., 1999 (link)], along with 11 non-diffusion weighted images (b = 0).

Shen K., Doré V., Rose S., Fripp J., McMahon K.L., de Zubicaray G.I., Martin N.G., Thompson P.M., Wright M.J, & Salvado O. (2016). Heritability and genetic correlation between the cerebral cortex and associated white matter connections. Human Brain Mapping, 37(6), 2331-2347.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!