Levamisole hydrochloride

Manufactured by Thermo Fisher Scientific

Sourced in United States

Levamisole hydrochloride is a chemical compound used in various laboratory and research applications. It functions as an anthelmintic, which means it is effective against parasitic worms. The compound is commonly utilized in biological and biochemical studies, particularly in the fields of immunology and parasitology.

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Levamisole (14 citations)

2 protocols using levamisole hydrochloride

Chemical Compound Preparation Protocol

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Solutions of potassium cyanide (Sigma Aldrich 60178-25G), sodium chloride (BioShop SOD002.205), cycloheximide (Sigma Aldrich C7698-1G), abamectin (Sigma Aldrich 31732) and 2-deoxy-D-glucose (Sigma Aldrich D8375) were prepared fresh to twice the working concentration in M9 buffer, 1.6% DMSO. Stock solutions of aldicarb (Sigma Aldrich, 33386) were prepared to 1 M in DMSO. Solutions of levamisole hydrochloride (Acros Organics, 16595-80-5), oxotremorine M (Sigma Aldrich, O100) and mecamylamine hydrochloride (Sigma Aldrich, M9020) were prepared to 100 mM in water. These solutions were divided into single use aliquots and frozen. Stocks of arecoline hydrobromide (Acros Organics, 250130050) and atropine sulfate monohydrate (Sigma Aldrich, A0257) were prepared fresh on the day of use in M9 buffer. (-)-Nicotine (Sigma Aldrich, N3876) was stored frozen, undiluted in single use aliquots. Compounds described in Burns et al. (2015) (link) were purchased as a custom library of 10 mM stock in DMSO (ChemBridge Corporation) and stored frozen.

Spensley M., Del Borrello S., Pajkic D, & Fraser A.G. (2018). Acute Effects of Drugs on Caenorhabditis elegans Movement Reveal Complex Responses and Plasticity. G3: Genes|Genomes|Genetics, 8(9), 2941-2952.

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Quantitative Analysis of Illicit Substances

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Cocaine hydrochloride (99.4%) was purchased from Lipomed (Arlesheim, Switzerland). Phenacetin (98.0%), diltiazem hydrochloride (p.a.), lidocaine hydrochloride monohydrate (p.a.), procaine hydrochloride (p.a.), hydroxyzine dihydrochloride (98.0%), benzocaine (p.a.), acetaminophen (99.0%), ephedrine hydrochloride (99.0%), creatine (p.a.), diphenhydramine hydrochloride (99.0%), phenylephrine hydrochloride (p.a.), ibuprofen (98.0%), antipyrine (98.0%), atropine (99.0%), ascorbic acid (99.0%) and myo-inositol (99.0%) were purchased from Sigma-Aldrich (St Louis, MO, USA). Benzoic acid (99.5%) and levamisole hydrochloride (99.0%) were purchased from Acros organics (Morris Plains, NJ, USA).

Eliaerts J., Dardenne P., Meert N., Van Durme F., Samyn N., Janssens K, & De Wael K. (2017). Rapid classification and quantification of cocaine in seized powders with ATR-FTIR and chemometrics. Drug testing and analysis, 9(10).

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