The largest database of trusted experimental protocols

Dicyclohexylcarbodiimide solution

Manufactured by Merck Group
Sourced in United States

Dicyclohexylcarbodiimide (DCC) solution is a chemical reagent commonly used in organic synthesis. It functions as a dehydrating agent, facilitating the formation of amide bonds between carboxylic acids and amines. The solution is typically employed in peptide synthesis and other coupling reactions.

Automatically generated - may contain errors

3 protocols using dicyclohexylcarbodiimide solution

1

Boronic Acid-Functionalized Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols
Carboxylatedpoly(vinyl chloride) (>97% GC) (PVCCOOH), bis-(2-ethylhexyl)sebacate (DOS), polycaprolactone (Mn 70,000-90,000) (PCL), tridodecylmethylammonium chloride (TDMAC), alizarin, 4-carboxy-3-fluorophenylboronic acid (1), 3-fluoro-4-methoxycarbonylphenylboronic acid (2a), D-(+)-glucose, tetrahydrofuran (≥ 99.9%) (THF), dicyclohexylcarbodiimide solution (60% w/v in xylene) (DCC), N-hydroxysuccinimide (NHS), aniline(≥ 99.5%), 1-propanol (anhydrous, 99.7%), 1-butanol (HPLC, 99.7%), 1-hexanol (98%), cyclohexanol(99%),sodium sulfate (anhydrous,≥ 99.9%), sodium chloride, ethyl acetate (anhydrous, 99.8%), hexane (anhydrous, 99.5%), N, N’-dimethylformamide (DMF) and N, N’-dimethylaminopyridine (DMAP) were purchased from Sigma Aldrich (St Louis, MO, USA). Octylboronic acid (>97%) and Citroflex A-6 were acquired from Synthonix (Wake Forest, NC, USA) and Vertellus (Indianapolis, IN, USA), respectively. Phosphate Buffered Saline (PBS) (1x, pH = 7.4) was purchased as a solution from Invitrogen (Carlsbad, CA, USA). Hydrochloric acid (1.0 N) and sodium bicarbonate were purchased from Fisher Scientific (Fair Lawn, NJ, USA). 1,2-distearoyl-snglycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] (ammonium salt) (DSPE-mPEG550) was purchased from Avanti Polar Lipids, Inc. SKH1-E mice were acquired from Charles River Laboratories International Inc. (Wilmington, MA).
+ Open protocol
+ Expand
2

Synthesis of CyTE-777-NHS Ester

Check if the same lab product or an alternative is used in the 5 most similar protocols
CyTE777 carboxylic acid (85 mg, 106.65 μmol) (Sigma-Aldrich, MO, USA) was introduced into a Reacti-Vial (Thermo Fisher Scientific, MA, USA) and dissolved in 500 μL of dry DMF. Then, 100 μL of dicyclohexylcarbodiimide solution (Sigma-Aldrich, MO, USA) in dry DMF (220.05 mg, 1.0665 mmol), 186.65 μL of 4-(dimethylamino) pyridine (Sigma-Aldrich, MO, USA) (134.387 mg, 1.1 mmol), and N-hydroxysuccinimide (Sigma-Aldrich, MO, USA) (NHS, 122.74 mg, 1.0665 mmol) were added, and the resulting reaction mixture was protected from light and stirred at room temperature for 12 h. The reaction was checked for completion through HPLC, and the resulting CyTE-777-NHS ester was used without further purification.
+ Open protocol
+ Expand
3

Rhodamine B-Functionalized Carbon Nanotubes

Check if the same lab product or an alternative is used in the 5 most similar protocols
Rhodamine B isothiocyanate (70% labeling efficiency), (3-aminopropyl) triethoxysilane (97%), 4-(dimethylamino)pyridine (≥99%), dicyclohexylcarbodiimide solution (≥99%), triethylamine BioUltra ≥99.5%, poly(diallyldimethylammonium chloride) (MW <100,000 Da), poly-(sodium 4 styrenesulfonate) (MW =70,000 Da), nitric acid (HNO3, 65%), sodium hydroxide (NaOH, ≥97%), tetraethyl orthosilicate (TEOS, 98%), and EtOH were obtained from Sigma-Aldrich Química SL (Madrid, Spain). Multiwalled carbon nanotubes 9.5 nm in diameter and 1.5 μm in length, 95% C purity, syn thesized using Catalytic Chemical Vapor Deposition process, were purchased from Nanocyl as a powder. Ammonium hydroxide solution (NH4OH, 28%–30% NH3), cystamine hydrochloride 97%, N,N-dimethylformamide were obtained from Fluka. Sulfuric acid (H2SO4, 96%) was purchased from Panreac and sodium chloride (NaCl, ≥99%) from Merck.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!