MRI was carried out in a 3.0 Tesla Siemens Trio Tim system with a 12-channel head coil at the Shanghai Key Laboratory of Magnetic Resonance (East China Normal University, Shanghai, China). All subjects’ head movements were minimized with a Siemens dedicated filler. T1-weighted anatomical images were collected using a 3-dimensional magnetization-prepared rapid-acquisition gradient-echo pulse sequence (repetition time = 2530 ms, echo time = 2.34 ms, inversion time = 1100 ms, flip angle = 7°, number of slices = 192, sagittal orientation, field of view = 256 × 256 mm2, matrix size = 256 × 256, slice thickness = 1 mm, 50% gap). Following this, subjects were asked to remain motionless, keep their eyes closed, and stay awake and relaxed. Resting-state images consisted of 210 volumes of a T2*-weighted gradient-echo echo planar imaging pulse sequence (33 slices of 3.5 mm thickness, repetition time = 2000 ms, echo time = 30 ms, flip angle = 90°, transverse orientation, field of view = 220× 220 mm2, matrix size = 64 × 64, 25% distance factor).
Dedicated filler
Manufactured by Siemens
The Dedicated Filler is a laboratory equipment designed for precise and consistent filling of containers. It operates by automatically measuring and dispensing a predetermined volume of liquid or semi-solid materials into various types of vessels. The core function of this device is to provide accurate and repeatable filling capabilities for a wide range of laboratory applications.
Automatically generated - may contain errors
3 protocols using dedicated filler
1
Resting-state fMRI Acquisition and Analysis
2
High-resolution MRI and DTI Acquisition
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Magnetic resonance imaging (MRI) was performed on a 3.0 Tesla Siemens Trio Tim system equipped with a 12-channel head coil at the Shanghai Key Laboratory of Magnetic Resonance (East China Normal University, Shanghai, China). The subjects were instructed not to move during the scans, and a Siemens dedicated filler was used to prevent head movement. High-resolution T1-weighted anatomical images were acquired by using a 3-dimensional magnetization-prepared rapid-acquisition gradient-echo pulse sequence (repetition time, 2530 ms; echo time, 2.34 ms; inversion time, 1100 ms; flip angle, 7°; number of slices, 192; sagittal orientation; field of view, 256×256 mm2; and voxel size, 1 × 1 × 1 mm3). The DTI acquisition utilized a single-shot spin-echo planar imaging sequence in the contiguous axial plane with the following parameters: repetition time, 8900 ms; echo time, 86 ms; b-values, 0 and 1000 s/mm2; diffusion direction, 64; number of slices, 70; field of view, 256 × 256 mm2; and voxel size, 2 × 2 × 2 mm3.
3
Diffusion Tensor Imaging of Whole Brain
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The MRI data were acquired on a Siemens 3T Trio MR scanner with a 12-channel phased array coil. DTI acquisition involved a single-shot, spin-echo planar imaging sequence in contiguous axial planes that covered the whole brain. Diffusion-sensitizing gradients were applied in 12 non-collinear directions, together with acquisition without diffusion weighting (b = 0). The imaging parameters were set to the following values: TR = 6,600 ms, TE = 89 ms, average = 4, b-value = 1,000 s/mm2, slice thickness = 2.5 mm, 50 slices. The matrix resolution was acquired at 128 × 128 and reconstructed to 256 × 256. The resolution was 2 × 2 × 2.5 mm3. The subjects were told not to move during the scans, and a Siemens dedicated filler was used to prevent head movement. The acquisition time for the scan was 6 minutes and 5 seconds.
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