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Resveratrol

Manufactured by LGC
Sourced in Canada

Resveratrol is a natural compound found in various plants, including grapes, berries, and nuts. It is a type of polyphenol that has been extensively studied for its potential health benefits. Resveratrol functions as an antioxidant, helping to neutralize free radicals and protect cells from oxidative stress.

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2 protocols using resveratrol

1

Analytical Standards for Polyphenol Analysis

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The standard compound polydatin, resveratrol, and formononetin (I.S) were purchased from Toronto Research Chemicals (Toronto, Canada, all compounds purity ≥ 99%). LC-MS grade acetonitrile and water were from EMD (Gibbstown, NJ, USA). Other chemicals were used as received.
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2

Quantifying Curcumin and Polyphenol Metabolites

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Curcumin (#218580100, Fisher; 97% by weight, with assayed composition 80.6% Curcumin, 13.5% demethoxyCurcumin, and 2.4% bisdemethoxyCurcumin) and Curcumin-glucuronide were purchased, with content/purity verified using LC/MS (see method below)[21 (link)]. Resveratrol (#R150000), Resveratrol-3-glucuronide (#R150015), quercetin dihydrate (#Q509500), quercetin −d3 (major) (#Q509502), and quercetin 3-O-β-D-glucuronide (#Q509510) were purchased from Toronto Research Chemicals. Stock solutions were prepared in DMSO. Primary antibodies recognizing GUSB (#ARP44234_T100, Aviva Systems Biology) and β-actin (#4968, Cell Signaling Technologies [CST]) were used in Western analyses. Saccharolactone (#S0375), and 4-methylumbelliferyl-glucuronide (4-MUG; #M9130) were purchased from Sigma Aldrich, and recombinant mouse receptor activator of NFκB ligand (RANKL, 462-TEC) from R&D Systems.
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