Desmethyl acetamiprid

We analyzed six compounds, five of which were mother compounds (Acetamiprid, Clothianidin, dinote-furan, imidacloprid, and thiamethoxam) and the other a metabolite (desmethyl-Acetamiprid). imidacloprid currently accounts for approximately 41.5% of the global neonicotinoid market in terms of sales, and this is followed by thiamethoxam (23.8%), Clothianidin (16.7%), and Acetamiprid (10.5%) 12) . dinotefuran accounts for approximately 3% of the global neonicotinoid market 12) . The major neonicotinoid compounds were therefore included in this study.
Acetamiprid, imidacloprid, and thiamethoxam were obtained from AccuStandard (New Haven, CT, USA). Clothianidin and dinotefuran were purchased from Wako Pure Chemical Industries (Osaka, Japan). Desmethyl-Acetamiprid was obtained from Sigma-Aldrich (St. Louis, MO, USA). Isotope-labeled Acetamiprid (Acetamiprid-d6) was purchased from Hayashi Pure Chemical Ind. (Osaka, Japan). Acetamiprid-d3, Clothianidin-d3, imidacloprid-d4, and thiamethoxam-d4 were obtained from Dr. Ehrenstorfer Inc. (Augsburg, Germany). dinotefuran-d3 was purchased from @rtMolecule (Poitiers, France). All reagents were of analytical grade.