Echospeed plus

MRI examinations were performed with a 1.5‐T MR scanner using a dedicated four‐channel phased array breast coil (Echospeed Plus with EXCITE II, GE Medical Systems, Milwaukee, USA). MRI protocols included a sagittal, 3D Vibrant SPGR sequence for dynamic imaging (TR = 6.4 ms, TE = 3.0 ms, TI = 7.0 ms, flip angle = 10°, slice thickness = 4 mm without any interslice gap, matrix size = 256 × 256, field of view = 20–22 cm, NEX = 1, ZIP2, and scan time per acquisition = 68 seconds); and an axial, fat‐suppressed, T1‐weighted pulse sequence with enhancement. The Vibrant sequence was continuously repeated six times, with one phase before and five phases after contrast enhancement for dynamic acquisition. The contrast agent (Gd‐DTPA) was injected into the antecubital vein by a power injector at a rate of 2.0 mL/second based on patient body mass (0.2 mmol/kg), followed by a saline flush. An initial fat‐saturated T1‐weighted precontrast scan was first collected. A first postcontrast scan was collected two minutes after contrast agent injection. Four subsequent postcontrast images were acquired at intervals of 90 seconds, resulting in five postcontrast images for each patient (t = 2, 3.5, 5, 6.5, and 8 minutes).

MRI Scans were performed on a 3.0T EXCITE HD MR imaging system (Echo-speed plus, General Electric, Milwaukee, WI, USA) with an 8NVHEAD-A coil using a three- dimensional, spoiled gradient recalled echo 3D-SPGR-T1 weighted sequence using the following parameters: repetition time (TR) = 7.7 ms; echo time = 1.6 ms; flip angle = 15′; number of excitations = 1; section thickness = 0.5 mm; field of view = 240 × 240 mm; and matrix size = 256 × 256 mm. The voxel size was 1 × 1 × 1 mm. The voxel-based morphometry was used to analyze the hippocampal volume, with the Biological Parametric Mapping (WFU PickAtlas Tool, http://fmri.wfubmc.edu/) and the MATLAB platform (version 7.0, Mathworks Inc. Sherbom, MA, USA) was used to calculate the hippocampal structure volume.