Medicagenic acid

Manufactured by Phytolab

Sourced in Germany

Medicagenic acid is a naturally occurring triterpenoid compound found in various plant species. It is a key component in the extraction and analysis of plant-derived compounds. Medicagenic acid serves as a reference standard for analytical procedures, enabling the identification and quantification of similar compounds in complex plant extracts. Its core function is to provide a reliable and well-characterized substance for use in research and quality control applications.

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Lab products found in correlation

2 protocols using medicagenic acid

Analytical Standards for UHPLC Analysis

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Ultrapure water with a resistivity of 18.2 MΩ·cm at 25 °C was generated with a Millipore™-purification system. Ultrahigh-Performance Liquid Chromatography (UHPLC)-grade MeOH, acetonitrile and formic acid were purchased from Biosolve (Dieuze, France), dichloromethane by Merck (Darmstadt, Germany). The following analytical standards were provided by Sigma–Aldrich (St. Louis, MO, USA): apigenin, benzoic acid, caffeic acid, +/− catechin, chlorogenic acid, cinnamic acid, coumarin, emodin, epicatechin, ferulic acid, isorhamnetin, naringenin, p-coumaric acid, protocatechuic acid, quercetin, quercitrin, rutin, salicylic acid, sinapic acid, β-sitosterol, stigmasterol, syringic acid, tannic acid, taxifolin, theophylline and vanillic acid. Luteolin and procyanidin B2 were provided by Santa Cruz Biotechnology (Santa Cruz, CA, USA). Gallic acid and p-hydroxybenzoic acid were provided by Carl Roth (Karlsruhe, Germany). Human liver S9 fraction and NADPH RS (Regenerating System) were purchased from XenoTech. Medicagenic acid was provided by Phytolab (Vestenbergsgreuth, Germany). All other chemicals and biochemicals were purchased from Sigma-Aldrich (St. Louis, MO, USA).

Peeters L., Van der Auwera A., Beirnaert C., Bijttebier S., Laukens K., Pieters L., Hermans N, & Foubert K. (2020). Compound Characterization and Metabolic Profile Elucidation after In Vitro Gastrointestinal and Hepatic Biotransformation of an Herniaria hirsuta Extract Using Unbiased Dynamic Metabolomic Data Analysis. Metabolites, 10(3), 111.

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Ultrapure water-based metabolic assay

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Ultrapure water with a resistivity of 18.2 MΩ.cm at 25 ℃ was generated with a Millipore™-purification system. UHPLC-grade methanol, acetonitrile and formic acid were purchased from Biosolve (Dieuze, France). Medicagenic acid was provided by Phytolab (Vestenbergsgreuth, Germany). Human liver S9 fraction and NADPH RS were purchased from Tebu Bio (Boechout, Belgium). All other chemicals and biochemicals were purchased from Sigma-Aldrich (St. Louis, USA).

Peeters L., Foubert K., Breynaert A., Schreurs G., Verhulst A., Pieters L, & Hermans N. (2022). Effects of medicagenic acid metabolites, originating from biotransformation of an Herniaria hirsuta extract, on calcium oxalate crystallization in vitro. Journal of ethnopharmacology, 285.

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