Completing a blood count with automated hematology analysis instruments (Beckman Coulter DxH 800 analyzer) allowed for the measurement of the counts of monocytes (MC), lymphocytes (LC), neutrophils (NC), and platelets (PC). The ratio of MC to LC was used to compute the MLR. The systemic immune-inflammation index (SII) was calculated as PC * NC/LC, the system inflammation response index (SIRI) as NC * MC/LC, the platelet-to-lymphocyte ratio (PLR) as PC/LC, and the neutrophil-lymphocyte ratio (NLR) as NC/LC. The history of PCa was the outcome variable of our study, which was evaluated by asking participants if they had ever received a diagnosis of the disease from a physician or another type of medical professional.
To gain more insight into MLR and PCA, we also investigated the relationship between inflammatory markers and PSA. The participants’ serum total PSA was obtained using Beckman Access at the Department of Laboratory Medicine Immunology Division. The serum total PSA concentration (ng/mL) was recorded by the Hybritech PSA technique.
To gain more insight into MLR and PCA, we also investigated the relationship between inflammatory markers and PSA. The participants’ serum total PSA was obtained using Beckman Access at the Department of Laboratory Medicine Immunology Division. The serum total PSA concentration (ng/mL) was recorded by the Hybritech PSA technique.