Mth1 nb100 109

Manufactured by Novus Biologicals

MTH1 (NB100-109) is a recombinant protein that can be used as a research tool. It is a member of the NUDIX hydrolase family and is involved in the regulation of cellular processes. The core function of MTH1 is to hydrolyze oxidized purine nucleoside triphosphates to their respective monophosphates, thereby preventing their incorporation into DNA and RNA.

Automatically generated - may contain errors

Lab products found in correlation

Total akt, by Cell Signaling Technology (2 mentions) Cleaved parp, by Cell Signaling Technology (2 mentions) Phospho akt, by Cell Signaling Technology (2 mentions) P erk1 2, by Cell Signaling Technology (2 mentions) Total erk, by Cell Signaling Technology (2 mentions) P21cip1 waf1, by Santa Cruz Biotechnology (2 mentions) Actin ab82266, by Abcam (2 mentions) P27kip1, by Santa Cruz Biotechnology (2 mentions)

Spelling variants of this product

NB100-109 (4 citations) Rabbit anti-MTH1 (NB100-109, (3 citations)

2 protocols using mth1 nb100 109

Western Blot Protein Detection

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

Western blotting was carried out as previously described ^{47 (link)}. Blots were probed with
antibodies against the following proteins: MTH1 (NB100-109, Novus Biologicals),
p53 (sc-126, Santa Cruz Biotech), p21^cip1/waf1 (sc-817, Santa Cruz
Biotech), phospho-Akt (4060, Cell Signaling) total Akt (9272, Cell Signaling),
cleaved-PARP (9541, Cell Signaling), p-Erk1/2 (9101, Cell Signaling), total Erk
(9102, Cell Signaling), p27^kip1 (sc-528, Santa Cruz Biotech), KRAS
(sc-30, Santa Cruz Biotech), tubulin (sc-8035, Santa Cruz Biotech), actin
(ab82266, Abcam) and GAPDH (ab9485, Abcam). Western blotting images represent
data consistent with a minimum of two independently established sets of samples.
Densitometry of images was carried out via the ImageJ Analyze Gels module.

Patel A., Burton D.G., Halvorsen K., Balkan W., Reiner T., Perez-Stable C., Cohen A., Munoz A., Giribaldi M.G., Singh S., Robbins D.J., Nguyen D.M, & Rai P. (2014). MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene, 34(20), 2586-2596.

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Western Blot Protein Detection

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

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