Hydroxycotinine

Manufactured by Merck Group

Sourced in United States

Hydroxycotinine is a metabolite of nicotine, produced in the body when nicotine is broken down. It is commonly used in laboratories for research and analysis purposes.

Automatically generated - may contain errors

Lab products found in correlation

Nicotine d4, by Merck Group (3 mentions) Cotinine d3, by Merck Group (3 mentions) Cotinine, by Merck Group (3 mentions) Nicotine, by Merck Group (3 mentions) Arecoline hydrobromide, by Merck Group (3 mentions) Guvacine hydrochloride, by Merck Group (3 mentions) Eugenol, by Merck Group (2 mentions) O eugenol, by Merck Group (2 mentions) Proteinase k, by Merck Group (1 mentions) Methanol meoh, by Thermo Fisher Scientific (1 mentions) Ammonium hydroxide, by Merck Group (1 mentions)

Spelling variants of this product

Trans-3’-hydroxycotinine (2 citations)

3 protocols using hydroxycotinine

Quantitative Analysis of Tobacco Alkaloids

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Arecoline hydrobromide, guvacine hydrochloride, nicotine, cotinine, hydroxycotinine, N′-nitrosonornicotine (NNN), N′-nitrosoanatabine (NAT), NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), NNK-d₃, nicotine-d₄, cotinine-d₃ and eugenol and o-eugenol were purchased from Sigma-Aldrich (St Louis, MO, USA), Guvacoline hydrobromide, N-nitrosoguvacoline, Arecaidine Hydrobromide, Arecodine-d₅, hydrobromide salt were purchased from Medical Isotopes (Pelham, NH). Proteinase K was purchased from Sigma-Aldrich (St Louis, MO, USA). All solvents were of LC-MS grade.

Franke A.A., Li X, & Lai J.F. (2015). Pilot study of the pharmacokinetics of betel nut and betel quid biomarkers in saliva, urine, and hair of betel consumers. Drug testing and analysis, 8(10), 1095-1099.

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Quantification of Tobacco Alkaloids

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Arecoline hydrobromide, guvacine hydrochloride, nicotine, cotinine, hydroxycotinine, NNN, NAT, NNK, 4-(Methyl-d₃-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK-d₃), nicotine-d₄, cotinine-d₃ and eugenol and o-eugenol were purchased from Sigma-Aldrich (St. Louis MO), Guvacoline hydrobromide, N-nitrosoguvacoline, Arecaidine Hydrobromide, Arecodine-d₅, hydrobromide salt were purchased from Medical Isotopes (Pelham, NH). All solvents were of LCMS grade and were purchased from Fisher Scientific (Waltham MA).

Franke A.A., Mendez A.J., Lai J.F., Arat-Cabading C., Li X, & Custer L.J. (2015). Composition of betel specific chemicals in saliva during betel chewing for the identification of biomarkers. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 80, 241-246.

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Quantifying Nicotine and Metabolites

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Ammonium hydroxide (NH₄OH), Arecoline hydrobromide, guvacine hydrochloride, nicotine, cotinine, hydroxycotinine, nicotine-d₄, and cotinine-d₃ were purchased from Sigma-Aldrich (St Louis, MO, USA). Guvacoline hydrobromide, Arecaidine hydrobromide, Arecodine-d₅, and hydrobromide salt were purchased from Medical Isotopes (Pelham, NH). Methanol (MeOH) was purchased from Fisher Scientific (Waltham, MA, USA). All solvents were of LCMS grade.

Franke A.A., Li X., Herzog T.A., Paulino Y.C., Badowski G., Wilkens L.R, & Lai J.F. (2022). Salivary Areca and tobacco alkaloids for bioverification in the Betel Nut Intervention Trial (BENIT). Drug testing and analysis, 15(1), 58-65.

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