80 insmr ch01

Manufactured by ALPCO

The 80-INSMR-CH01 is a laboratory instrument designed for in-situ measurement and analysis. It provides the capability to perform real-time monitoring and data collection within a controlled environment.

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Lab products found in correlation

Freestyle lite blood glucose monitoring system, by Abbott (1 mentions)

2 protocols using 80 insmr ch01

Propargite Effects on Murine Glucose Homeostasis

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All animal work has been approved by IACUC committee of Weill Cornell Medical College. CD-1 adult male mice were treated with different doses of propargite or vehicle (corn oil) through intraperitoneal injection for 5 days. Fasting blood glucose level were monitored every day using Abbott FreeStyle Lite blood glucose monitoring system. Then, CD-1 adult male mice were treated with 12 mg/kg propargite or vehicle (corn oil) through intraperitoneal injection for 5 days. Fasting blood was collected via tail nicking following 14–16 h of fasting with ad libitum access to drinking water. Serum mouse insulin levels were assessed by ELISA (80-INSMR-CH01, Alpco). Mice were then killed. The pancreases were embedded in OCT. The tissue was then sectioned at 5 μm for immunohistochemistry staining analysis of DNA damage marker γ-H2A.X and β-cell marker INS.

Zhou T., Kim T.W., Chong C.N., Tan L., Amin S., Sadat Badieyan Z., Mukherjee S., Ghazizadeh Z., Zeng H., Guo M., Crespo M., Zhang T., Kenyon R., Robinson C.L., Apostolou E., Wang H., Xiang J.Z., Evans T., Studer L, & Chen S. (2018). A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival. Nature Communications, 9, 4815.

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Plasma Insulin Quantification in Fasted Mice

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Blood was drawn from the saphenous vein of mice fasted for 4 h. Heparinized blood was centrifuged at 2,000 g for 15 min at 4°C to separate plasma. Insulin was quantified using STELLUX Chemiluminescent Immunoassays (ALPCO, 80-INSMR-CH01).

Wu D., Wong C.K., Han J.M., Orban P.C., Huang Q., Gillies J., Mojibian M., Gibson W.T, & Levings M.K. (2020). T reg–specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome. The Journal of Experimental Medicine, 217(8), e20191542.

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