Verio 3.0 t mri scanner

All study subjects were diagnosed with Siemens Verio3.0T MRI scanner, and all patients underwent MRI plain scan, enhanced scan, and DWI scan. Axial and coronal rapid small-angle excitation 2D sequence T1WI scanning parameters were as follows. The repetition time (TR) was 250 ms, the echo time (TE) was 250 ms, the scanning field (FOV) was 185 mm × 220 mm, and the matrix was 216 × 265. The T2WI scanning parameters of the fast spin echo sequence and fat suppression sequence were as follows: TR = 3900 ms, echo time TE = 92 ms, FOV was 189 mm × 30 mm, and matrix was 256 × 256. The T1C image scanning parameters were as follows: TR = 650 ms, TE = 9.17 ms, FOV = 200 mm, and layer thickness = 5 mm. The resolution of all MRI images was 512 × 512, and the tumor area and lymph nodes were delineated by two experienced clinicians.
MRI diagnostic criteria for NPC: NPC tumor tissue was equal or slightly high signal, and the surrounding tissue of the tumor was enhanced, but the surrounding tissue was not enhanced.

The patient was supine and the Siemens Verio 3.0T MRI scanner was used to scan the body with a twelve-element chest phased-array body coil. Routine plain scan: T2WI coronal, T1WI transverse and sagittal; T2WI transverse and sagittal; then multiphase dynamic contrast (DCE-MRI) scans. Dynamic enhancement was performed using a 3D VIBE T1-weighted dynamic perfusion sequence scan, with all sequences using free breathing. Multi-flip angle scan before dynamic enhanced scan, scan parameters: TR 3.25 ms, TE 1.17 ms, Flip Angle: 5°, 10°, 15°, field of view 350 mm × 282 mm, matrix 162 × 288, layer thickness 5 mm, The number of layers was 30, and the time resolution of each period was 6.5 s. Dynamic enhanced scanning sequence parameters: Flip Angle 10°, scanning 35 phases, the remaining parameters were the same as above, the total time of multi-flip angle scanning and dynamic enhanced scanning was 247 s. When the dynamic enhanced scan was in phase 3, a high-pressure syringe was used to inject the contrast agent gadolinium diamine (Omniscan, Ge Healthcare) through the median cubital vein. The injection dose was 0.1 mmol/kg, the injection speed was 3.0 ml/s, followed by a 20 mL saline flush.

All patients underwent unenhanced and enhanced MRI scans (10 mL Gd-EOB-DTPA at 0.25 mmol/mL, Germany Bayer Healthcare Co.) using a Siemens Verio 3.0 T MRI scanner with a 12-channel body phased-array coil. Images were obtained with HASTE, TSE T2WI axial free breathing with fat suppression, EPI DWI axial breath hold with fat suppression, T1WI VIBE axial fat suppression plain and enhanced scanning. The Gd-EOB-DTPA was administered as a bolus, which was injected at a rate of 2 mL/s through the cubital vein; this was followed by a 20 mL saline chaser, which was administered at the same rate. For all patients, T1WI VIBE with syngo MapIt included: repetition time (TR) 3.9 ms, echo time (TE) 1.4 ms, flip angle 5° and 15°,field of view (FOV) 273 × 380 mm, Matrix 161X320 mm, 3 mm section thickness, and parallel imaging technique (P = 2) with generalized auto-calibrating partially parallel acquisition (GAPPA), performed for T1 mapping on pre-enhanced, 5, 10 and 20 min delay phases after Gd-EOB-DTPA administration.

All patients underwent plain and enhanced MR imaging (10 mL Gd-EOB-DTPA at 0.25 mmol/mL, Germany Bayer Healthcare Co.) using a Siemens Verio 3.0 T MRI scanner with a 12-channel body phased-array coil. Gd-EOB-DTPA was administered as a bolus injected at a rate of 2 mL/s through the cubital vein followed by a 20 mL saline chaser administered at the same rate. The scanning parameters of T1WI volume interpolated body examination (VIBE) were repetition time (TR) 3.9 ms, echo time (TE) 1.4 ms, flip angle 15°, field of view (FOV) 350 mm, matrix 168 × 320, voxel size 1.6 × 1.1 × 4.5 mm, signal to noise ratio (SNR) 1.00, 4.5 mm section thickness. The scanning parameters of T2WI using BLADE technique were TR 2930 ms, TE 189 ms, FOV 400 mm, voxel size 1.3 × 1.3 × 6.0 mm, SNR 1.00, 6 mm section thickness. The scanning parameters of diffusion-weighted imaging (DWI) were TR 9000 ms, TE 66 ms, FOV 420 mm, matrix 80 × 148, voxel size 3.5 × 2.8 × 6.0 mm, SNR 1.00, 6 mm section thickness. Delay phase scanning was at 5, 10 and 20 min after Gd-EOB-DTPA administration.

All subjects were scanned in a 3.0 T Verio MRI scanner (Siemens, Erlangen, Germany) equipped with an 8-channel parallel head coil and were required to lie quietly in the scanner while staying awake with their eyes closed. All of the PD patients were in a medication-on state during MRI inspection. Both functional and structural images were obtained. The resting-state functional images were acquired with echo-planar imaging (EPI) with the following parameters: repetition time (TR) = 2000 ms; echo time (TE) = 21 ms; slice thickness/gap = 4 mm/0.6 mm; acquisition matrix = 64 × 64; flip angle = 78°; voxel size = 3.5 mm × 3.5 mm × 4.0 mm; and field of view (FOV) = 224 × 224 mm². Sagittal T1-weighted images were obtained with the following parameters: TR/TE = 1900 ms/2.19 ms; acquisition matrix = 256 × 256; flip angle = 9°; voxel size = 1.0 mm × 1.0 mm × 1.0 mm; slice thickness/gap = 1 mm/0.5 mm.

We acquired images using a Siemens 3.0 T Verio MRI scanner with a 64-channel phased array head coil. For functional imaging, we used T2*-weighted gradient-echo echo-planar imaging (EPI) sequences with the following parameters: time repetition (TR) = 2500 ms, echo time (TE) = 25 ms, flip angle (FA) = 90°, field of view (FOV) = 192 mm², matrix = 64 × 64. We acquired 42 contiguous slices with a thickness of 3 mm, in an interleaved order. Moreover, we acquired from each participant a high resolution anatomic T1-weighted image (1-mm isotropic resolution).