activities of the CYP3A family (Luciferin-PFBE, Cat # V8901), CYP3A4
(Luciferin-IPA, Cat # V9001), and CYP2C19 (Luciferin-H EGE, Cat
# V8881) following the manufacturer's instructions. Results are
shown as Luminescent Counting Units (LCU)/minute normalized to a million viable
cells. Cell viability was assessed by Trypan Blue Stain (Invitrogen).
Metabolically well-characterized aHeps (Life Technologies HMCPMS Lot# Hu8138)
were used as positive controls.