Aquillion one

Multislice NCCT, preoperative multiphase CTA-SI, and follow-up NCCT of at least 24 h to assess the final infarct size were performed in our center with (1) A 320-detector Toshiba (Aquillion One Toshiba Medical Systems Co., Tokyo, Japan), (2) A 64-detector Toshiba (Aquillion CX Toshiba Medical Systems Co., Tokyo, Japan), and (3) A 64-detector Philips (IQon Philips Healthcare, USA).
Continuous axial sections parallel to the orbitomeatal line of NCCT were obtained from the base of the skull to vertex. Coverage of CTA varied from skull base to vertex, C7 to vertex, and aortic arch to vertex. The contrast was injected at a flow rate of 4–5 cc/s with a total volume of 70–90 cc. The patients from other hospitals that indicated for endovascular thrombectomy performed multislice NCCT with single-phase CTA before referring to our center.

All patients in the Dan-NICAD trial underwent coronary CTA scans on a 320-slice volume CT scanner (Aquillion One, Toshiba Medical Systems, Japan) according to clinical guidelines.
CT imaging analysis included an Agatston calcium score and evaluation of CAD including luminal diameter stenosis estimation in each segment of the coronary tree using an 18-segment model. Coronary lesions were evaluated blinded to patient history. Stenosis severity was classified in all segments with a reference vessel diameter >2 mm. Severe stenosis was defined as 50–100% diameter reduction (≈70% to 100% area reduction). Segments with suspected severe stenosis and non-evaluable segments with a reference vessel diameter >2 mm were defined as having obstructive CAD by coronary CTA and referred to ICA.

Participants were scanned using 320-detector row computed tomography (Aquillion ONE; Toshiba Medical Systems Corporation, Tokyo, Japan). A nonenhanced prospective electrocardiogram was performed to measure the CAC score with the following parameters: rotation time, 275 ms; slice collimation, 0.5 mm; slice thickness, 3.0 mm; tube voltage, 100 kV; and automatic tube current modulation (SURE Exposure 3D standard; Toshiba Medical Systems Corporation, Otawara, Japan). Images were analyzed in a core workstation by using dedicated software (TeraRecon V. 4.4.11.82.3430.Beta; TeraRecon, Foster City, CA). The CAC score was measured using the Agatston method.^{[29 (link),30 (link)]}The total CAC score was the sum of all individual calcified lesions identified within the area of the coronary arteries. CAC scores >100 U indicated CAC.^{[22 (link),31 (link)]}

CT scanning was performed on a 320-detector-row CT scanner (Aquillion ONE; Toshiba Medical Systems Corporation, Tokyo, Japan). The protocol consisted of acquisition of a CT volume data covering the entire phantom with eight different tube current values, i.e., 100, 120, 140, 160, 180, 200, 250, and 290 mAs for all three phantom models. The detailed CT parameters were as follows: tube energy 120 kVp; collimation 80 × 0.5 mm; rotation time 0.5 seconds; and pitch 0.75. The computed tomography dose index (CTDI) and the dose length product (DLP) were recorded for each mAs. An automatic tube current modulation software (^SureExposure 3D, Toshiba Medical Systems Corporation, Otawara, Japan) was not used as it can produce minor changes in the tube current-time product settings in each scan. Instead, eight fixed-tube, current-time product settings were used as they can deliver exactly the same image noise as predicted. Other benefits of the use of a fixed tube current technique could include better comparability and reproducibility with CT scanners from other manufacturers. The phantom was positioned within the isocenter of the CT scanner with its cross-section perpendicular to the scanner's z-axis.