Mylab twice

A last generation ultrasound machine (Esaote MyLab Twice, Esaote s.p.a., Genova, Italy) equipped with software to perform MicroV analysis was adopted to acquire IOUS images with the MicroV technique. The ultrasound machine was provided by a linear 3–11 MHz multifrequency probe (LA332, Esaote s.p.a., Genova, Italy).
Standard parameters to be set on Esaote MyLab Twice machine at the beginning of the IOUS acquisition are listed below (Table 1).

US images of breast masses were obtained using a Resona 7/7S/9 scanner (Mindray, China), and MyLab TM Twice (Esaote, Italy) equipped with a 3- to 11-MHz linear probe and a 4- to 13-MHz linear probe by one of seven senior radiologists with 5–15 years of experience in conventional US and at least 2 years of experience in CEUS of the breast. The nodule size was defined by the maximal diameter on US. The number and location of the masses were also recorded. If multiple masses were present, the most suspicious (the higher BI-RADS category) or the largest mass was targeted. The machine settings were adjusted to obtain optimal US images, and the images were stored for further analysis.

ESAOTE MyLab^TMTwice was used to measure the RTE. After identification of the target lesion, the transducer was kept in a stable position without pressure, perpendicularly, to better minimize the compression artifact, and RTE mode was implemented over the conventional ultrasound image. The operator vibrates the probe, and the vibration frequency is kept at 2 times per second. The pressure index is controlled at 3–4. A color signal box of appropriate size was displayed as a colored area, with softer tissue presented as green or red and the harder presented as blue. When the images are stable, the operator freezes the image and selects the satisfactory image for analysis. The elastic ratio of the ablation area and normal liver tissue was measured three times and the average of the measured values was taken. The areas of the ablation zone were calculated according to the dimension of the ablation zone. The standard for satisfactory images is as follows: (1) the pressure is appropriate, and the images are clear and stable; (2) the liver tissue surrounding the ablation zone indicated uniform yellow-green color. The area of the ablation zone was calculated, according to the elastic images (Figure 2).