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Hispeed

Manufactured by GE Healthcare
Sourced in United States

The HiSpeed is a laboratory equipment product from GE Healthcare. It is designed to provide high-speed processing capabilities for various laboratory applications. The core function of the HiSpeed is to facilitate efficient and rapid handling of samples and materials within a laboratory setting.

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4 protocols using hispeed

1

CT-based Tissue Characterization Protocol

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General Electric Hi Speed (GE, Hi Speed, USA) diagnostic X-ray CT scanner is used to estimate an average HU value over a number of slices at 120 kVp,
150 mAs, 9 slices and one pitch. Spiral and axial scanning mode are used at 10 mm intervals.
One cm2 of region of interest (ROI) was selected on each image and an HU value determined within each ROI. Linear attenuation coefficients
are calculated according to CT number values using standard definition:
HU=(μmaterial-μwater)(μwater-μair)×1000(2)
Where μwater and μair are the linear attenuation coefficients of water and air, respectively. This definition is for CT scanner calibrated
with water reference. A change of one Hounsfield unit (HU) represents a change of 0.1% of the μ of water since the μ of air is nearly zero.
Data were analyzed by SPSS 16 software and compared by T-test statistically based on which a significance level was p<0.05.
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2

Imaging Protocol for Postoperative Tumor Surveillance

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Upper abdominal contrast-enhanced CT or MRI scans were carried out every month for the first 3 months post-operatively. If no tumor residue or tumor recurrence was detected, a re-examination was carried out every 3-6 months (CT: HiSpeed or LightSpeed QX/i, GE Medical Systems; Milwaukee, WI; contrast agent: Ultravist 300 [injection speed was fixed as 3ml/s]; Schering, Berlin, Germany; MRI: Discovery MR750 3.0T; GE Medical Systems; contrast agent: Gd-DTPA [injection speed was fixed to 3ml/s]; GE Healthcare, IDA Business Park Carrigtohill, Ireland).
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3

BNCT for Recurrent Head and Neck Cancer

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For this study, nine patients with recurrent H&N cancer underwent simulated computed tomography (CT) simulation according to the standard protocol of Taipei Veterans General Hospital for BNCT. Four patients had oral cavity cancer, two had oropharyngeal cancer, and one patient each had mandibular sarcoma, a parotid gland tumor and hypopharyngeal cancer. The median accumulated radiotherapy photon dose before BNCT was 66 (range, 60–102) Gy. CT data were acquired with a simulator (HiSpeed; GE Healthcare, Waukesha, WI, USA) according to our institution’s standard protocol, which included the collection of 5-mm slice thicknesses with a 38.4-cm field of view while patients were in the supine position. All patients provided written consent for storage of their medical information in the hospital database and for research use. The study has been approved by Institutional Review Board, Taipei Veterans General Hospital No.2012-06-016A#7 and conducted according to the principles expressed in the Declaration of Helsinki. The individuals in this manuscript (or their relative) have given written informed consent to publish the case details and images.
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4

Femur Biomechanical Testing Protocol

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Eleven fresh-frozen femurs (Table 1) from eight donors who did not suffer from cancer or musculoskeletal pathologies (other than osteoporosis) were obtained through an ethically-approved international donation program (http://www.iiam.org/). Bone quality and lack of defects were verified through Dual-energy X-ray absorptiometry (DXA: Eclipse, Norland Co., USA), and computed tomography scanning (CT: Hi-Speed, General Electric, USA). The femurs were wrapped in cloths soaked with physiological solution during the whole procedure to avoid dehydration, and stored at -20°C when not in use. Biomechanical length (BL) and diameter of the head (HD)
were measured as in (Cristofolini_et_al.,2009 ). An anatomical reference frame was marked on each femur (Cristofolini,2012) . After resecting the condyles, the distal end of each specimen was embedded in acrylic bone cement in an aluminum pot (100-mm deep) so that 33% of the biomechanical length was free (Fig. 1).
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