Nano zs instrument

Manufactured by Malvern Panalytical

Sourced in United Kingdom

The Nano ZS instrument is a dynamic light scattering (DLS) system used for the measurement of particle size and zeta potential. It is capable of analyzing particles, emulsions, and molecules with sizes ranging from 0.3 nanometers to 10 micrometers. The Nano ZS provides highly accurate and reliable data on the hydrodynamic size and surface charge characteristics of a wide range of materials.

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Lab products found in correlation

Dts software, by Malvern Panalytical (4 mentions) Zetasizer software, by Malvern Panalytical (3 mentions) Uv grade cuvettes, by Thermo Fisher Scientific (2 mentions) Milli q water, by Merck Group (1 mentions) H 7650, by Hitachi (1 mentions) Equinox 55, by Bruker (1 mentions) Asap 2020, by Micromeritics (1 mentions) Jem 1230 microscope, by JEOL (1 mentions) Ultima 4, by Rigaku (1 mentions) Themis z, by Thermo Fisher Scientific (1 mentions) Multimode 8, by Bruker (1 mentions) Jem f200, by JEOL (1 mentions) Ht7700, by Bruker (1 mentions) Escalab 250xi spectroscope, by Thermo Fisher Scientific (1 mentions) Xcalibur, by Thermo Fisher Scientific (1 mentions) Bi 200sm, by Brookhaven Instruments (1 mentions) D8 advance, by Bruker (1 mentions) Rf 6000, by Shimadzu (1 mentions) Jem 1230, by Hitachi (1 mentions) Hrtem, by Hitachi (1 mentions)

Spelling variants of this product

Nano ZS (1243 citations) Malvern Zetasizer Nano ZS instrument (17 citations) Malvern Nano ZS instrument (12 citations) Nano instrument (9 citations) Zetasizer Nano ZS DLS instrument (9 citations) Zetasizer Nano ZS ZEN3600 instrument (5 citations) Nano Series ZS Instrument (3 citations) Nano ZS dynamic light scattering instrument (3 citations) Zetasizer Nano ZS Dynamic Light Scattering Instrument (3 citations) Zetasizer Nano Series instrument (Nano ZS, (2 citations)

63 protocols using nano zs instrument

CLA-PTX and PTX Nanoparticle Formulation

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The ratio of CLA-PTX:DSPE-PEG was set at 1:0.0125, 1:0.025, 1:0.05, 1:0.1, 1:0.15, 1:0.2, 1:0.33, 1:1, 1:3, 1:5, 1:7, 1:10, 1:20, 1:40 or 1:80 (w/w). The concentration of CLA-PTX was 2 mg/ml. According to the CLA-PTX NPs prparation, a volume of 0.3 ml CLA-PTX mixed DSPE-PEG DMSO solution was added drop-wise to 3 ml distilled water under continuous and gentle stirring (300–500 rpm) at room temperature. The particle size of CLA-PTX NPs was determined by dynamic light scattering (DLS) measurements on a Nano-ZS instrument (Malvern, Worcestershire, UK).
As a control group, the CLA-PTX was replaced by PTX. Similarly, the ratio of PTX:DSPE-PEG was set at 1:0.0125, 1:0.025, 1:0.05, 1:0.1, 1:0.15, 1:0.2, 1:0.33, 1:1, 1:3, 1:5, 1:7, 1:10, 1:20, 1:40 or 1:80 (w/w). The concentration of PTX was 2 mg/ml. According to the CLA-PTX NPs preparation, a volume of 0.3 ml of PTX mixed DSPE-PEG DMSO solution was added drop-wise to 3 ml distilled water under continuous and gentle stirring (300–500 rpm) at room temperature. The particle size of the PTX particles was determined by dynamic light scattering (DLS) measurements on a Nano-ZS instrument (Malvern, Worcestershire, UK).

Zhong T., Yao X., Zhang S., Guo Y., Duan X.C., Ren W., Dan H.u.a.n.g., Yin Y.F, & Zhang X. (2016). A self-assembling nanomedicine of conjugated linoleic acid-paclitaxel conjugate (CLA-PTX) with higher drug loading and carrier-free characteristic. Scientific Reports, 6, 36614.

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Zeta Potential Characterization of Dendrimers

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Zeta potential measurements were performed on a Nano ZS instrument (Malvern Panalytical Ltd, Malvern, UK), with a He–Ne laser (633 nm), using an electrophoretic light scattering technique. The analyses were done at 25.0 ± 0.1 °C with dendrimer solutions at 100 µM in Milli-Q water (Merck KGaA, Darmstadt, Germany), and analyzed with the Smoluchowski model.

Fruchon S., Bellard E., Beton N., Goursat C., Oukhrib A., Caminade A.M., Blanzat M., Turrin C.O., Golzio M, & Poupot R. (2019). Biodistribution and Biosafety of a Poly(Phosphorhydrazone) Dendrimer, an Anti-Inflammatory Drug-Candidate. Biomolecules, 9(9), 475.

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Preparation and Characterization of CLA-PTX Nanoparticles

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The concentration of CLA-PTX was 1, 2, 5, 10, 15, 20 and 30 mg/ml, respectively. DSPE-PEG was added to the CLA-PTX DSMO solution at a ratio of CLA-PTX:DSPE-PEG = 1:0.1 (w/w). According to the CLA-PTX NP preparation, a volume of 0.3 or 1.0 ml CLA-PTX mixed DSPE-PEG DMSO solution was added drop-wise to 3 ml distilled water under continuous and gentle stirring (300–500 rpm) at room temperature. After dialysis against distilled water for 48 h (MWCO = 3500 Da), the particle size of CLA-PTX NPs was determined by dynamic light scattering (DLS) measurements on a Nano-ZS instrument (Malvern, Worcestershire, UK).

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Characterization of mUPR@ Ru(POP) Nanoparticles

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The morphology, particle size, and zeta potential of mUPR@ Ru(POP) were characterized by transmission electron microscopy (TEM; H-7650; Hitachi Ltd., Tokyo, Japan) and Nano-ZS instrument (Malvern Instruments, Malvern, UK). The Fourier transform infrared (FTIR; Equinox 55; Bruker, Ettlingen, Germany) spectroscopy was conducted in the range of 4,000−500 cm⁻¹.

Yang F., Fang X., Jiang W, & Chen T. (2017). Bioresponsive cancer-targeted polysaccharide nanosystem to inhibit angiogenesis. International Journal of Nanomedicine, 12, 7419-7431.

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Synthesis and Characterization of Citrate-Coated Gold Nanoparticles

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Quasi-spherical citrate-coated gold nanoparticles (AuNPs) were synthesized according to the modified Lee–Meisel method [57 (link)]. Tetrachloroauric acid was reduced by sodium borohydride (0.1%) in the presence of sodium citrate (1%) as stabilizing agent. Morphology and size distribution of the particles obtained were assessed by a FEI Tecnai G² 20 X-Twin (Field Electron and Ion Company (FEI) Corporate Headquarters, Hillsboro, OR, USA) transmission electronmicroscope at an acceleration voltage of 200 kV, furthermore, additional size and surface charge measurements were performed by a Zetasizer Nano ZS instrument (Malvern, Worchestershire, UK). The optical properties of the obtained nanoparticles were assessed by spectral analysis. Absorbance spectra were recorded using an Ocean Optics 355 DH-2000-BAL ultraviolet–visible (UV–Vis) spectrophotometer (Halma PRC, Largo, FL, USA) within the 300–800 nm range.

Igaz N., Szőke K., Kovács D., Buhala A., Varga Z., Bélteky P., Rázga Z., Tiszlavicz L., Vizler C., Hideghéty K., Kónya Z, & Kiricsi M. (2020). Synergistic Radiosensitization by Gold Nanoparticles and the Histone Deacetylase Inhibitor SAHA in 2D and 3D Cancer Cell Cultures. Nanomaterials, 10(1), 158.

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Functionalized Mesoporous Silica Nanoparticles

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Mesoporous silica nanoparticles functionalized with
Gd₂O₃ and fluorophore (fluorescein or tetramethyl
rhodamine isothiocyanate) (FITC-Gd₂O₃-MSN) were
manufactured following a previously reported synthesis^{21 (link)} and stored at room temperature. An
aliquot of this synthesis, which yielded over 1 gram of dried MSN, was further
functionalized with trifluoropyl moieties by grafting (3, 3, 3) trifluoropropyl
trimethoxysilane onto the surface under reflux with toluene. Similarly, MSN with
fluorophore only (FITC-MSN) and MSN with other metals
(Fe₃O₄-FITC-MSN; Bi₂O₃-FITC-MSN; Au-FITC-MSN) were synthesized. Size and morphology
homogeneity were characterized by X-ray diffraction (XRD), using a Rigaku Ultima
IV diffractometer, nitrogen sorption analysis in a Micromeritics ASAP 2020
surface area and porosity analyzer using the Brunauer-Emmett-Teller (BET)
equation to calculate surface area and pore volume and the
Barrett-Joyner-Halenda (BJH) equation to calculate the pore size distribution.
Dynamic light scattering (DLS) was used to obtain particle size distribution and
zeta potential data, using the Malvern Zetasizer Nano ZS instrument (University
of Iowa, Department of Chemistry). The materials were also visualized by
transmission electron microscopy (TEM) by supporting samples on copper grids in
a JEOL JEM 1230 microscope operating at 40–120 kV(University of Iowa,
Central Microscopy Research Facility).

Sweeney S., Adamcakova-Dodd A., Thorne P.S, & Assouline J.G. (2017). Biocompatibility of Multi-Imaging Engineered Mesoporous Silica Nanoparticles: In Vitro and Adult and Fetal In Vivo Studies. Journal of biomedical nanotechnology, 13(5), 544-558.

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Characterization of Wastewater Foulant Properties

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The relative hydrophobicity of foulant samples was measured as described by Pembrey et al. [23 (link)]. The zeta potentials of samples were recorded using a Zetasizer Nano ZS Instrument (Malvern, Malvine, UK). Atomic force microscopy (AFM) images (not shown) were taken with the non-contact mode (XE7, Park, Suwon, Korea). The average roughness and the fractal dimension were obtained from XEI software provided by the AFM manufacturer. Standard analytic methods were used to measure the COD, NH₄⁺-N, MLSS, and MLVSS [24 ].

Yan L., Li R., Song Y., Jia Y., Li Z., Song L, & Zhang H. (2019). Characterization of the Fouling Layer on the Membrane Surface in a Membrane Bioreactor: Evolution of the Foulants’ Composition and Aggregation Ability. Membranes, 9(7), 85.

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Comprehensive Material Characterization Protocol

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TEM and AFM images of STPE-PMNSs were obtained from Hitachi HT7700 and Bruker MultiMode 8, respectively. STEM-HAADF images were obtained from Themis Z (Thermo Scientific). Zeta potential and size of STPE-PMNSs were measured on Nano-ZS instrument (Malvern Instruments Limited) and Brookhaven BI-200SM, respectively. FT-IR was obtained from Nicolet 7000-c. The fluorescence emission spectra were measured on a fluorescence spectrophotometer (Shimadzu, RF-6000). XRD patterns were recorded on an X-ray diffractometer (Bruker D8 Advance) with Cu Kα radiation (λ = 1.54060 Å) and XPS was measured on Thermo ESCALAB 250Xi spectroscope. HRTEM and EDXS were performed on a JEOL JEM-F200. ¹H NMR, ¹³C NMR, and ³¹P NMR spectra were obtained on Bruker nuclear resonance (400 MHz) spectrometer. HRMS data was collected on Thermo Scientific Xcalibur.

Wang J., Zhao X., Tao Y., Wang X., Yan L., Yu K., Hsu Y., Chen Y., Zhao J., Huang Y, & Wei W. (2024). Biocompatible aggregation-induced emission active polyphosphate-manganese nanosheets with glutamine synthetase-like activity in excitotoxic nerve cells. Nature Communications, 15, 3534.

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Characterization of TCNCoT Nanomaterials

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A transmission electron microscope (TEM, JEM-1230, Japan) and high-resolution transmission (HRTEM, Hitachi, Tokyo, Japan) were used to investigate the morphology of TCNCoT. X-ray photoelectron spectroscopy (XPS) and high-resolution XPS spectra were collected by an Axis Ultra DLD X-ray photoelectron spectrometer. X-ray diffraction (XRD) patterns were obtained by a Bruker D8 diffractometer with high-intensity Cu-Kα radiation. The zeta potentials were measured using a Zetasizer Nano-ZS instrument (Malvern ZEN3600, UK). Electron spin resonance (ESR) spectra were recorded using a JEOL JES-FA200 electron spin resonance spectrometer. PL emission spectra were measured using an FLS 980 series of fluorescence spectrometers.

Ni Y., Wang J., Wang M., Liu L., Nie H., Wang Q., Sun J., Yue T., Zhu M.Q, & Wang J. (2022). COVID-19-inspired “artificial virus” to combat drug-resistant bacteria by membrane-intercalation- photothermal-photodynamic multistage effects. Chemical Engineering Journal, 446, 137322.

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Polymer Characterization Protocols

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¹H NMR spectra were measured using a Varian liquid-state NMR operated at 400 MHz. Molecular weights of polymers were determined using a Waters 1515 gel permeation chromatography (GPC) coupled with a RI detector, in reference with a series of polystyrene standards with tetrahydrofuran (THF) as the eluent. Shimadzu RF-5301 spectrofluorophotometer (Shimadzu Scientific Instruments, Columbia, MD) was used for fluorescence measurements. Dynamic light scattering (DLS) measurements for micelle diameters were performed using a Malvern Nano-ZS instrument (Worcestershire, UK) equipped with a 4 mW He–Ne laser (633 nm) with an output at a scattering angle of 173°. The solution was passed through a 0.45 μm Nylon micro-filter (VWR, Batavia, IL) to remove dust before the DLS measurements.

Wu S., Su F., Magee H.Y., Meldrum D.R, & Tian Y. (2019). cRGD functionalized 2,1,3-benzothiadiazole (BTD)-containing two-photon absorbing red-emitter-conjugated amphiphilic poly(ethylene glycol)-block-poly(ε-caprolactone) for targeted bioimaging. RSC Advances, 9(59), 34235-34243.

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