Brilliance 40 channel multi detector ct

The TyG index was determined using ln (triglycerides [mg/dL] ×glucose [mg/dL]/2). All subjects were categorized into four groups based on the quartiles of the TyG index level. CAC scores were calculated using the Agatston method [14 (link)]. CAC progression was defined as a diference ≥ 2.5 between the square roots (√) of the baseline and follow-up CACSs (Δ√transformed CACS) considering inter-scan variability [15 (link)]. Annualized Δ√transformed CACS was defined as Δ√transformed CACS divided by the inter-scan period.
Multi-detector CT scanners used to assess CAC had at least 16 slices (Philips Brilliance 256 iCT, and Philips Brilliance 40-channel multi-detector CT, GE 64-slice Lightspeed, Siemens 16-slice Sensation). All centers performed standard prospective or retrospective methods.
Diabetes was defined as either a fasting glucose level ≥ 126 mg/dL, HbA1C level ≥ 6.5%, a referral diagnosis of diabetes, or use of anti-diabetic treatment [16 (link)].

Multi-detector CT scanners used to assess CAC had at least 16 slices (Siemens 16-slice Sensation, Philips Brilliance 256 iCT, Philips Brilliance 40 channel multi-detector CT, and GE 64-slice Lightspeed). CAC scores were calculated using the Agatston method [18 (link)]. The square root transformed difference was calculated [√CAC score (follow-up)—√CAC score (baseline)], and CAC progression was defined as a square root transformed difference of >2.5 to minimize the effect of interscan variability [19 (link), 20 (link)]. For participants with more than two CT scans, the square root transformed difference was calculated for each follow-up CT scan, and the earliest follow-up scan with demonstrated CAC progression was included in the analysis. The CAC progression rate was calculated as the annualized difference between the square root of the baseline and last follow-up CAC scores.