Shikonin sk

Manufactured by Tokyo Chemical Industry

Sourced in Japan

Shikonin (SK) is a natural pigment derived from the roots of the Lithospermum erythrorhizon plant. It is a reddish-purple compound with applications in various industries. Shikonin exhibits antioxidant, anti-inflammatory, and antimicrobial properties, making it a versatile compound for potential use in various research and development applications.

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Lab products found in correlation

Doxorubicin dox, by Merck Group (2 mentions) Anti crt, by Abcam (1 mentions) Anti β actin antibody, by Abcam (1 mentions) Hrp conjugated secondary antibody, by Abcam (1 mentions) Anti hsp70, by GeneTex (1 mentions) Anti hmgb1, by GeneTex (1 mentions) Rapamycin, by LC Laboratories (1 mentions)

2 protocols using shikonin sk

Immune-modulating Compounds in Cancer

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Shikonin (SK) was purchased from Tokyo Chemical Industry (Tokyo, Japan), and doxorubicin (Dox) was from Sigma (St. Louis, MO, USA). The three antibodies used for depletion of specific DAMP proteins in tumor cell lysate (TCL) were anti-HSP70 (rabbit plyoclonal; GeneTex), anti-CRT (rabbit polyclonal; Abcam) and anti-HMGB1 (rabbit plyoclonal; GeneTex). The same antibodies and anti-β-actin antibody (rabbit polyclonal; Abcam) were also used as primary antibodies for western blot analyses. HRP-conjugated secondary antibody (goat polyclonal; Abcam) was used as a secondary antibody.

Lin T.J., Lin H.T., Chang W.T., Mitapalli. S P., Hsiao P.W., Yin S.Y, & Yang N.S. (2015). Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components. Molecular Cancer, 14, 174.

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Evaluation of Shikonin, Rapamycin, and Doxorubicin

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Shikonin (SK) was purchased from Tokyo Chemical Industry (Tokyo, Japan). Rapamycin was from LC Laboratories (St. New Boston, MA, USA), and doxorubicin (DOX) was from Sigma (St. Louis, MO, USA).

Lin T.J., Liang W.M., Hsiao P.W., M. S P., Wei W.C., Lin H.T., Yin S.Y, & Yang N.S. (2015). Rapamycin Promotes Mouse 4T1 Tumor Metastasis that Can Be Reversed by a Dendritic Cell-Based Vaccine. PLoS ONE, 10(10), e0138335.

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