Chloromethyl chlorosulfate

Manufactured by Merck Group

Sourced in France

Chloromethyl chlorosulfate is a laboratory chemical compound used as a reagent in various synthesis and analysis procedures. It is a colorless to pale yellow liquid with a pungent odor. The compound is primarily used as a chlorinating and sulfonating agent in organic chemistry. No further details on its intended use or applications are provided.

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Lab products found in correlation

2 protocols using chloromethyl chlorosulfate

Synthesis and Characterization of Squalene Derivatives

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All the chemicals used were of analytical grade. Squalene (SQ), diglycolic anhydride, ethyl chloroformate, chloromethyl chlorosulfate, ammonium acetate, n-Bu₄NHSO₄, TES, and triethylamine (TEA) were purchased from Sigma-Aldrich (France). Pd-C was obtained from Alfa Aesar (France). DiD and DiR were purchased, respectively, from PromoKine (Germany) and Interchim (France). Roti-Histofix 4% (formaldehyde) was provided by Roth (Germany).
All the drugs used were of analytical grade. Morphine sulfate salt pentahydrate, λ-carrageenan, naloxone hydrochloride (Nal, μ, δ, and κ opioid receptors antagonist), and naloxone methiodide (Nal-M, a nonspecific opioid receptor antagonist that does not cross the BBB) were purchased from Sigma-Aldrich (Saint-Quentin-Fallavier, France). Ketamine and xylazine were purchased from Centravet (Maisons-Alfort, France). LENK and Alloc-LENK were purchased from Ontores Biotechnologies (Zhejiang, China).

Feng J., Lepetre-Mouelhi S., Gautier A., Mura S., Cailleau C., Coudore F., Hamon M, & Couvreur P. (2019). A new painkiller nanomedicine to bypass the blood-brain barrier and the use of morphine. Science Advances, 5(2), eaau5148.

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Synthesis of Novel Functionalized Compounds

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Acetic acid, β-alanine, 1-aminopropan-2-ol, 3-azidopropanol, 2,2′-azobis(2-methylpropionitrile), 6-(Boc-amino)hexanoic acid, chloromethyl chlorosulfate, chloromethyl pivalate, dibenzocyclooctyne-amine, dicyclohexylcarbodiimide, 4-(dimethylamino)pyridine, ethyl chloroformate, ethyldiisopropylamine, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, methacryloyl chloride, mebendazole, 4-nitrobenzyl chloroformate, phosgene solution, silica gel, sodium hydride, tetrabutylammonium hydrogen sulfate, tetramethylurea, thiazolidine-2-thione, and trifluoroAcetic acid were purchased from Sigma-Aldrich (Prague, Czech Republic). Acetonitrile, methanol and other common solvents and chemicals were purchased from Merck (Prague, Czech Republic). All chemicals and solvents were of analytical grade.

Studenovský M., Rumlerová A., Kostka L, & Etrych T. (2021). HPMA-Based Polymer Conjugates for Repurposed Drug Mebendazole and Other Imidazole-Based Therapeutics. Polymers, 13(15), 2530.

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