Ivermectin

Manufactured by Yuanye Bio-Technology

Sourced in United States, Canada

Ivermectin is a broad-spectrum antiparasitic agent. It is a semi-synthetic derivative of the avermectin class of macrocyclic lactone compounds. Ivermectin acts by inhibiting the transmission of nerve impulses in invertebrate organisms.

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Lab products found in correlation

1 chloro 2 4 dinitrobenzene, by Merck Group (2 mentions) L glutathione reduced, by Merck Group (2 mentions) Eugenol, by Merck Group (1 mentions) Plumbagin, by J&K Scientific (1 mentions) Acetylthiocholine iodine, by Merck Group (1 mentions) 2 methoxy 1 4 naphthoquinone, by Merck Group (1 mentions) 5 5 dithiobis 2 nitrobenzoic acid, by Merck Group (1 mentions)

2 protocols using ivermectin

Biochemical Assays Using Purchased Reagents

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Eugenol (98%), acetylthiocholine iodine, 5,5′-dithiobis(2-nitrobenzoic acid), L-reduced glutathione and 1-chloro-2,4-dinitrobenzene were purchased from Sigma-Aldrich Co. Ltd. (St. Louis, USA); and ivermectin (95%) were purchased from Shanghai Yuanye Biotechnology Co. Ltd. (Shanghai, China).

Shang X.F., Dai L.X., Yang C.J., Guo X., Liu Y.Q., Miao X.L, & Zhang J.Y. (2020). A value-added application of eugenol as acaricidal agent: The mechanism of action and the safety evaluation. Journal of Advanced Research, 34, 149-158.

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Naphthoquinones and Analogs Acquisition

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Naphthoquinones and their analogs (Fig. 2) were purchased from the following companies: juglone (97%), lapachol (97%), 2,3- dichloro-1,4-naphthoquinone (98%), vitamin K1 (98%), and naphthazarin (98%) were purchased from Aladdin Industrial Co. Ltd. (Shanghai, China); plumbagin (97%) was purchased from J&K Scientific Ltd. (Beijing, China); menadione (98%), 1,4-naphthoquinone (99%), shikonin (97%) and lawsone (98%) were purchased from Meryer Chemical Technology Co. Ltd. (Shanghai, China); 2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone (97%) was purchased from Tokyo Chemical Industry Co. Ltd. (Tokyo, Japan); 2-methoxy-1,4-naphthoquinone (98%), 2,3-dibromo-1,4-naphthoquinone (97%), acetylthiocholine iodine, 5,5′-dithiobis(2-nitrobenzoic acid), L-reduced glutathione and 1-chloro-2,4-dinitrobenzene were purchased from Sigma-Aldrich Co. Ltd. (St. Louis, USA) and from Toronto Research Chemical Inc. (Toronto, Canada); and alkannin (98%) and ivermectin (94%) were purchased from Shanghai Yuanye Biotechnology. Co. Ltd. (Shanghai, China).

Shang X.F., Liu Y.Q., Guo X., Miao X.L., Chen C., Zhang J.X., Xu X.S., Yang G.Z., Yang C.J., Li J.C, & Zhang X.S. (2018). Application of Sustainable Natural Resources in Agriculture: Acaricidal and Enzyme Inhibitory Activities of Naphthoquinones and Their Analogs against Psoroptes cuniculi. Scientific Reports, 8, 1609.

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