Ethanolamine

Manufactured by Spectrochem

Sourced in India

Ethanolamine is a colorless, viscous liquid chemical compound. It is a primary alkanolamine with the chemical formula C₂H₇NO. Ethanolamine serves as a core component in various industrial and laboratory applications, but a detailed description of its specific functions and intended uses is not available.

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Lab products found in correlation

2 protocols using ethanolamine

Synthetic Lipid Nanoparticle Preparation

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Fmoc-amino acids, p-toluene sulfonic acid, dicyclohexylcarbodiimide (DCC), 4-dimethylaminopyridine, and 1-bromo tetradecane were delivered from Sigma Aldrich. The organic solvents and chemicals, including ethanolamine, potassium carbonate, piperidine, dimethylformamide (DMF), methylene dichloride (DCM), and ethyl acetate, were purchased from Spectrochem Pvt. Ltd., and Finar Limited. Molecular mass analyses were performed by High-Resolution Mass Spectrometry (HRMS) using Agilent Q-TOF 6230, and the purity of final lipids was characterized by HPLC (Shimadzu LC Solution). ¹H-NMR (400 MHz) and ¹³C-NMR (101 MHz) spectra were recorded on Bruker AVANCE spectrometer, with TMS as an internal standard. DOPE (1,2-dioleoyl-sn-glycerol-3-phosphoethanolamine) was purchased from Sigma Aldrich. Agarose and 6× loading dye were purchased from Hi-media, India. All chemicals for biological applications were procured from Merck, Sigma-Aldrich, Thermo Fischer Scientific, and Invitrogen.

Manturthi S., Narayan K.P, & Patri S.V. (2022). Dicationic amphiphiles bearing an amino acid head group with a long-chain hydrophobic tail for in vitro gene delivery applications. RSC Advances, 12(51), 33264-33275.

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Synthesis and Characterization of Novel Lipid-based Nanocarriers

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Oleic acid (technical grade,
90%), 2-(dimethylamino)ethanol, 3-(dimethylamino)-1-propanol, cholesterol,
6-(p-toluidino)-2-naphthalenesulfonic acid sodium
salt (TNS), cholesterol distearoylphosphatidylcholine (DSPC), and
MPEG-2000-DSPE sodium salt were purchased from Sigma-Aldrich. Acryloyl
chloride was obtained from Alfa Aesar. 3-Amino-1-propanol, ethanolamine,
4-(dimethylamino)pyridine (DMAP), and 1-hydroxybenzotriazole (HOBt)
were obtained from Spectrochem (India). Triethylamine (TEA) and thionyl
chloride were obtained from SD Fine Pvt. Ltd. (India). 1-(3-Dimethylaminopropyl)-3-ethyl
carbodiimide hydrochloride (EDAC) was purchased from Sisco Research
Laboratories Pvt. Ltd (India). Dichloromethane (DCM), tetrahydrofuran
(THF), and other solvents used were of analytical grade. Precoated
silica-gel 60F₂₅₄ plates used for thin-layer chromatography
(TLC) to monitor reactions were obtained from Merck. Water used in
the entire study was obtained from the Milli-Q water purification
system of Millipore Corporation (Bedford).

Dhumal D.M., Patil P.D., Kulkarni R.V, & Akamanchi K.G. (2020). Experimentally Validated QSAR Model for Surface pKa Prediction of Heterolipids Having Potential as Delivery Materials for Nucleic Acid Therapeutics. ACS Omega, 5(49), 32023-32031.

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