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2 protocols using acetonitrile

1

Aspirin Synthesis and Purification

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Aspirin (ASP-I) was obtained as an ex-gratis from Jackson Laboratories Pvt. Ltd., Amritsar. India. Diethyl ether was purchased from Qualikem Fine Chem Pvt. Ltd., New Delhi, India.
Acetonitrile and dichloromethane were purchased from Central Drug House Pvt. Ltd., New Delhi, India. All the other reagents were of analytical grade. Triple distilled water was used wherever required.
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2

Raloxifene-Naringin Lipid Formulations

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Raloxifene hydrochloride (RLX) was provided by Aarti Drugs Ltd. (New Delhi, India) while naringin hydrate (NRG) and KBr were obtained from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Labrasol®, Labrafac®, Precirol ATO5®, Transutol®, Labrafil®, Caproyl 90®, Capmul MCM®, Gelucire 50/13®, Gelucire 48/16®, and Compritol 888 ATO® were generously provided by Gattefosse (Saint-Priest, France). Soyabean oil, peanut oil, sesame oil, corn oil, glyceryl monostearate, and sunflower oil were purchased from Loba Chemie (Chennai, India). Methanol, acetonitrile, ethyl oleate, PEG 400, Tween 80®, D-mannitol, methylene chloride, and hydrochloric acid were received from Central Drug House Pvt. Ltd. (Chennai, India). Almond oil, olive oil, castor oil, and 2,2-diphenyl-1-picrylhydrazyl (DPPH) were obtained from SRL Pvt. Ltd. (Chennai, India). Oleic acid, rhodamine B, and stearic acid were received from Sigma-Aldrich (New Delhi, India). The other materials utilized in this work were of standard analytical quality and used as received from their commercial source.
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