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255 protocols using skyra scanner

1

Resting-State fMRI in Psychotic Disorders

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MR imaging was performed at the ISMMS using either a 3T Siemens Allegra scanner or a 3T Siemens Skyra scanner with a 12-channel dedicated head coil. All individuals were instructed to lie still, and motion was minimized by using foam pads to secure individuals’ heads. During the resting state fMRI scan all individuals were instructed to “rest, but stay awake with your eyes closed.” We acquired a 6-minute blood oxygen level dependent (BOLD) scan using a T2*-weighted echo planar sequence in 39 individuals (16 HC, 12 individuals with SPD and 11 individuals with schizophrenia) on the Siemens 3T Allegra (matrix=64×64, slices=32, 3.28 × 3.28 × 3.0 mm3 voxel size, TR=2s, flip angle=90 degrees and 180 volumes). In addition, a 3D T1-weighted MP-RAGE provided 208 slices in a 256×256 matrix (TR=2500 ms, TE=4.4 ms, FOV=21 cm, slice thickness = 0.82 mm). In 69 individuals (27 HC, 33 participants with SPD and 9 individuals with schizophrenia) we acquired a 10-minute blood oxygen level dependent (BOLD) scan on the Siemens Skyra scanner using a T2*-weighted echo planar sequence (matrix = 98×98, slices=60, 2.33 × 2.33 × 2.33 mm3 voxel size, TR = 2s, flip angle = 60 degrees, and 300 volumes). In addition, a 3D T1-weighted MP-RAGE provided 244 slices in a 320×320 matrix (TR=2400 ms, TE=2.07, FOV=25.6 cm, slice thickness=.80 mm).
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2

Comparative Analysis of Primate Diffusion MRI

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This study evaluates variability in diffusion-weighted measurements across sites available in the PRIME-DE project, as well as between human MRI scanner models and vendors used to acquire the images. From the 25 sites in the database, 8 gathered diffusion data, and only 4 have a fair number of subjects (N ≥ 4): Aix-Marseille University (Aix-Marseille, 4 subjects, Siemens Prisma scanner), University of California, Davis (UC-Davis, 19 subjects, Siemens Skyra scanner), Mount Sinai School of Medicine—Philips (Sinai-Philips, 9 subjects, Philips Achieva scanner), and Siemens (Sinai-Siemens, 6 subjects, Siemens Skyra scanner). All subjects are Macaca Mulatta primates, anesthetized before acquisition. The scan sequence parameters can be found in Table 1. All datasets were acquired using 3T systems, with DWI at spatial resolutions from 0.7 to 1.4 mm3–isotropic or rectangular voxels—and anatomical images from 0.3 to 0.8 mm3 isotropic voxels.
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3

Phonological Task fMRI Acquisition Protocol

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Participants lay in the scanner with a response button box placed in their right hand. Visual stimuli were projected onto a screen, viewed via a mirror attached to the inside of the head coil, to keep participants focused on the task so that they would respond in time. Participants wore earphones to hear the auditory stimuli and two ear pads were used to attenuate the scanner noise. The two phonological task runs were counterbalanced across participants.
Images were acquired using 3.0T Skyra Siemens scanner with a 64-channel headcoil. The blood oxygen level dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired with multiband EPI (TE = 30 ms, flip angle = 80, matrix size = 128 × 128, FOV = 256 mm, slice thickness = 2 mm without gap, number of slices = 56, TR = 1250 ms, Multi-band accel.factor = 4, voxel size = 2 × 2 × 2). A high resolution, T1 weighted 3D image was acquired. The following scan parameters were used: TR = 1900 ms, TE = 2.34 ms, matrix size = 256 × 256, field of view = 256 mm, slice thickness = 1 mm, number of slices = 192.
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4

Multimodal Neuroimaging of Cognitive Tasks

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Participants lay in the scanner with a response button box placed in their right hand. To keep participants focused on the task, visual stimuli were projected onto a screen, viewed via a mirror attached to the head coil. Participants wore earphones to hear the auditory stimuli, and two pads placed in between the earphones and the head coil were used to reduce movement and attenuate scanner noise.
Images were acquired using a 3.0 T Skyra Siemens scanner with a 64-channel head coil. The blood oxygen level dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired with multiband EPI. The following parameters were used: TR = 1,250 ms, TE = 30 ms, flip angle = 80°, matrix size = 128 × 128, FOV = 256 mm2, slice thickness = 2 mm without gaps, number of slices = 56, multiband acceleration factor = 4, voxel size = 2 × 2 × 2 mm. A high resolution T1-weighted MPRAGE scan was acquired with the following scan parameters: TR = 1,900 ms, TE = 2.34 ms, matrix size = 256 × 256, FOV = 256 mm2, slice thickness = 1 mm, number of slices = 192.
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5

Phonological Processing in Neuroimaging

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Participants lay in the scanner with a response button box placed in their right hand. To keep participants focused on the task so that they would respond in time, visual stimuli were projected onto a screen, viewed via a mirror attached to the inside of the head coil. Participants wore earphones to hear the auditory stimuli and two ear pads were used to attenuate the scanner noise. The two phonological task runs were counterbalanced across participants.
Images were acquired using 3.0 T Skyra Siemens scanner with a 64-channel head coil. The blood oxygen level dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired with multiband EPI (TE=30 ms, flip angle=80, matrix size=128 × 128, FOV=256 mm2, slice thickness=2 mm without gap, number of slices=56, TR=1250 ms, Multi-band accel. factor=4, voxel size=2 × 2 × 2 mm). A high resolution T1 weighted MPRAGE scan was acquired with the following scan parameters: TR=1900ms, TE=2.34ms, matrix size=256 × 256, field of view=256 mm2, slice thickness=1 mm, number of slices=192.
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6

fMRI Study of Phonological Processing

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Participants lay in the scanner with a response button box placed in their right hand. To keep participants focused on the task so that they would respond in time, visual stimuli were projected onto a screen, viewed via a mirror attached to the inside of the head coil. Participants wore earphones to hear the auditory stimuli and two ear pads were used to attenuate the scanner noise. The two phonological task runs were counterbalanced across participants.
Images were acquired using 3.0T Skyra Siemens scanner with a 64-channel head coil. The blood oxygen level dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired with multiband EPI (TE=30ms, flip angle=80, matrix size=128x128, FOV=256mm2, slice thickness=2mm without gap, number of slices=56, TR=1250ms, Multi-band accel. factor=4, voxel size=2x2x2mm). A high resolution T1 weighted MPRAGE scan was acquired with the following scan parameters: TR=1900ms, TE=2.34ms, matrix size=256x256, field of view=256mm2, slice thickness=1mm, number of slices=192.
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7

Neuroimaging of Phonological Processing

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Participants lay in the scanner with a response button box placed in their right hand. Visual stimuli were projected onto a screen, viewed via a mirror attached to the inside of the head coil. Participants wore earphones to hear the auditory stimuli and two ear pads were used to attenuate the scanner noise. The two phonological task runs were counterbalanced across participants.
Images were acquired using 3.0 T Skyra Siemens scanner with a 64-channel head coil. The blood oxygen level dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired with multiband EPI (TE = 30 ms, flip angle = 80, matrix size = 128 × 128, FOV = 256 mm, slice thickness = 2 mm without gaps, number of slices = 56, TR = 1250 ms, Multi-band accel.factor = 4, voxel size = 2 × 2×2). A high resolution, T1 weighted 3D image was acquired. The following scan parameters were used: TR = 1900 ms, TE = 2.34 ms, matrix size = 256 × 256, field of view = 256 mm, slice thickness = 1 mm, number of slices = 192.
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8

Multiband fMRI Acquisition Protocol

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A 3.0 Tesla Skyra Siemens scanner with a 64-channel head coil was used to acquire all fMRI images. Functional images were acquired using a susceptibility weighted single-shot echo planar imaging (EPI) method with the following parameters: TR = 1,250 ms, TE = 30 ms, multiband acceleration factor = 4, flip angle = 80°, FOV = 256 × 256 mm, voxel size = 2 × 2 × 2 mm, number of slices = 56. A high-resolution T1-weighted structural image was also acquired using the following parameters: TR = 1,900 ms, TE = 2.43 ms, flip angle = 9°, FOV = 256 × 256 mm, voxel size = 1 × 1 × 1 mm, number of slices = 192.
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9

Functional MRI Acquisition Protocol

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Participants were positioned in the MRI scanner with their head secured using foam pads. An optical response box was placed in the participant’s right hand to log responses. Visual indicators (blue and yellow circles) were projected onto a screen, which participants viewed via a mirror attached to the inside of the head coil. Sound stimuli were presented via MRI compatible insert earphones (Sensimetrics, Model SI4) with disposable tips. Additionally, participants wore sound attenuating headphones to minimize the effects of the ambient scanner noise. Images were acquired using a 3.0-Tesla Skyra Siemens scanner with a 64-channel head coil. The blood-oxygen-level-dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired using a multiband acquisition with a factor of four. Four evenly spaced slices of the brain were acquired simultaneously. The following parameters were used: TE = 30ms, flip angle = 80 degrees, matrix size = 128×128mm2, field of view= 256mm, slice thickness = 2mm (no gap), number of slices = 56, TR = 1250ms. Voxel size = 2×2×2mm3. Before functional image acquisition, a high resolution T1-weighted 3D structural image was acquired for each subject (TR = 1900ms, TE = 2.43ms, matrix size = 256×256mm2, field of view = 256mm, slice thickness = 1mm, number of slices = 192).
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10

Phonological Processing in Neuroimaging

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Participants lay in the scanner with a response button box placed in their right hand. To keep participants focused on the task so that they would respond in time, visual stimuli were projected onto a screen, viewed via a mirror attached to the inside of the head coil. Participants wore earphones to hear the auditory stimuli and two ear pads were used to attenuate the scanner noise. The two phonological task runs were counterbalanced across participants.
Images were acquired using 3.0 T Skyra Siemens scanner with a 64-channel head coil. The blood oxygen level dependent (BOLD) signal was measured using a susceptibility weighted single-shot echo planar imaging (EPI) method. Functional images were acquired with multiband EPI (TE=30 ms, flip angle=80, matrix size=128 × 128, FOV=256 mm2, slice thickness=2 mm without gap, number of slices=56, TR=1250 ms, Multi-band accel. factor=4, voxel size=2 × 2 × 2 mm). A high resolution T1 weighted MPRAGE scan was acquired with the following scan parameters: TR=1900ms, TE=2.34ms, matrix size=256 × 256, field of view=256 mm2, slice thickness=1 mm, number of slices=192.
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