We construct a three-dimensional model of a patient-specific aortic root from pre-procedural computed tomography (CT) images of a female patient selected for TAVR with a 26 mm Medtronic CoreValve Evolut R at UNC Medical Center (Figs. 1a and 1b ). The images used in this study were obtained under UNC Institutional Review Board study number 18-0202. Since the native valve leaflets are not clearly captured in the patient’s images, we construct idealized volumetric native aortic valve leaflets (Fig. 1c ) based on measurements from Sahasakul et al.33 (link) and trim them in SOLIDWORKS (Dassault Systèmes SOLIDWORKS Corporation, Waltham, MA, USA) to fit within the reconstructed anatomy. Supplemental Materials Section A provides additional details.
Our model of the Evolut R is constructed from a CT scan of a 26 mm Medtronic CoreValve Evolut R device performed at UNC School of Medicine’s Biomedical Research Imaging Center. We create a discrete representation of the stent frame (Fig. 2a ) by placing a series of points along the stent in the CT images. We then generate a volumetric model of the device’s porcine pericardial sealing skirt (Fig. 2b ) around the stent frame and of the device’s porcine pericardial leaflets (Fig. 2c ) using measurements of the physical device. Additional details are included in Supplemental Materials Section B .
Our model of the Evolut R is constructed from a CT scan of a 26 mm Medtronic CoreValve Evolut R device performed at UNC School of Medicine’s Biomedical Research Imaging Center. We create a discrete representation of the stent frame (