A total of 24 h after the surgical procedure, the 16 surviving rats in the operation group were randomized to a myocardial infarction group (n=8) and curcumin group (n=8). The rats in the curcumin group were treated with intragastric administration of 150 mg/kg/body weight curcumin (Sinopharm Chemical Reagent Co., Ltd., Shanghai, China) once a day, as previously described (5 (link)). The rats in the other groups were given distilled water of the same volume.
Curcumin
Manufactured by Sinopharm
Sourced in China
Curcumin is a natural compound derived from the turmeric plant. It is a yellow-colored powder that is commonly used as a food coloring and dietary supplement. Curcumin has been studied for its potential antioxidant and anti-inflammatory properties, but its core function is as a chemical compound with various industrial and research applications.
Automatically generated - may contain errors
Lab products found in correlation
Cupric acetate, by Sinopharm (1 mentions)
Trimesic acid, by Sinopharm (1 mentions)
Iodized oil, by Tokyo Chemical Industry (1 mentions)
Diethylnitrosamine den, by Tokyo Chemical Industry (1 mentions)
Phosphate buffered saline (pbs), by Thermo Fisher Scientific (1 mentions)
Lysozyme, by Sinopharm (1 mentions)
Milli q water purification system, by Merck Group (1 mentions)
Pvp k90, by Merck Group (1 mentions)
Tween 80, by Sinopharm (1 mentions)
Porcine pepsin, by Yuanye Bio-Technology (1 mentions)
Bile extract, by Yuanye Bio-Technology (1 mentions)
Porcine mucin, by Yuanye Bio-Technology (1 mentions)
Porcine pancreatin, by Yuanye Bio-Technology (1 mentions)
Trypsin, by Sinopharm (1 mentions)
Casein, by Sinopharm (1 mentions)
Oil red o stain, by Solarbio (1 mentions)
Ecm medium, by ScienCell (1 mentions)
Eo20po70eo20, by Merck Group (1 mentions)
Agno3, by Sinopharm (1 mentions)
Vanillin, by Sinopharm (1 mentions)
14 protocols using curcumin
1
Curcumin Administration Post-Myocardial Infarction
2
Synthesis of Copper-Curcumin Nanocomposite
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Cupric acetate, trimesic acid, and curcumin were purchased from Sinopharm Chemical Reagent (Shanghai, China). PVP (MW = 29000) and NaHS were purchased from Sigma-Aldrich. Ethanol was bought from the exploration platform of Shanghai Titan Technology Co., Ltd (Shanghai, China). All reagents were used without further purification.
3
Curcumin-Loaded Lecithin Nanoparticles for Lung Cancer
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Curcumin was provided by Sinopharm Reagent Co., Ltd. (Shanghai, China). Soybean lecithin (SPC>90%) and cholesterol were purchased from Shanghai Taiwei Medicine Co., Ltd. (China) and Sinopharm Reagent Co., Ltd. (Shanghai, China), respectively. Gemcitabine was provided by Jiangsu Hansoh Pharmaceutical Co., Ltd., China. 3-Methylcholanthrene (MCA, TRC, USA), diethylnitrosamine (DEN, Tokyo Chemical Industry, Japan) and iodized oil (Guerbet, French) were used for generating rat primary lung cancer models. All other chemicals and solvents were of analytical grade or high performance liquid chromatographic (HPLC) grade. Pure water prepared with the Heal Force Pure Water System and was always used.
4
Antiviral and Antimicrobial Efficacy of Curcumin
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Curcumin (>98%) was purchased from Sinopharm Chemical Reagent Co. Ltd., China. Gram-negative Escherichia Coli (E.coli, ATCC 25922), Gram-positive Bacillus subtilis (B. subtilis, CMCC 63501), Fungus Penicillium (A S 3.4042) and Fungus Aspergillus niger (A.niger, A S 3.3928) were purchased from the Center for Conservation Biotechnology in Shanghai, China. Lysogeny broth (LB), Bengal red medium (BRM), Potato Dextrose Agar Medium (PDA), and phosphate-buffered saline (PBS) were purchased from Thermo Fisher Scientific, America. Soya casein digest lecithin polysorbate (SCDLP) were purchased from Cyclokay Microorganism, China. Propidine iodide (PI), and SYBR Green (SG) dye were purchased from Sigma-Aldrich. Porous PTFE membrane and PET non-woven fabric were obtained from Jiangsu Jiulang High-Tech Co., Ltd, China. KN95 Particulate Respirator was purchased from Zhengzhou Wanshenshan Healthcare PPE Co., Ltd, China. Single-use medical face mask was purchased from Zhende medical supplies Co., Ltd, China. The African green monkey kidney cell (Vero-E6) and Dulbecco's Modified Eagle Medium (DMEM) were obtained from Jiangsu Provincial Center for Disease Control and Prevention, China. All other chemicals were purchased from Sinopharm Chemical Reagent Co. Ltd., China, and used without further purification. Water used in all experiments was purified by deionization.
5
Curcumin and Lysozyme Purification Protocol
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Curcumin (95.0% purity), as well as lysozyme (Ly, 14.3 kDa) from chicken egg white, was purchased from Sinopharm Chemical Reagent Co., Ltd. Other chemicals were of reagent grade and used without purification. All solutions used in the experiments were prepared using ultrapure water through a Millipore (Millipore) Milli‐Q water purification system.
6
Fabrication of Curcumin-Loaded Polymer Nanofibers
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PVP K90 (white powder, Mn = 130,000) and poly (3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV, natural origin, PHV content = 8 mol%) were obtained from Sigma-Aldrich Trading Co., Ltd. (Shanghai, China). 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP, C3H2F6O, 99%), ethanol, curcumin, Tween 80, and phosphate-buffered saline (PBS) buffer were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). All the above chemical reagents were not further purified before preparing the spinning solution.
7
Curcumin-loaded Pullulan Microparticles
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Casein (obtained from milk, composed of watersoluble substance ≤3.0%, fat ≤0.7%, ash ≤3.0%, and moisture ≤12.0%), trypsin (biological reagent, ≥50,000 U/g), and curcumin were purchased from Sinopharm Chemical Reagent Co. Ltd. The MA was supplied by Hefei Bomei Biotechnology Co. Ltd. Pullulan was purchased from Aladdin Bio-Chem Technology Co. Ltd. The purity of pullulan is 98%, and the average molecular weight of pullulan is 300,000 Da. Maize embryo oil was purchased from COFCO Food Marketing Co. Ltd. Porcine mucin, porcine pepsin (3,000-3,500 NFU/ mg), porcine pancreatin (4,000 U/g), and bile extract (>60% glycodeoxycholic acid) were obtained from Yuanye Bio-Technology Co. Ltd. All other chemicals were of analytical grade.
8
Niacin and Curcumin for HASMC
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Niacin and curcumin were purchased from Sinopharm Chemical Reagents Co., Ltd (Beijing, China). ECM medium and human aortic smooth muscle cells (HASMCs) were purchased from ScienCell Co., Ltd (San Diego, USA). ELISA kits were purchased from Multi Sciences Co., Ltd (Shanghai, China). Other materials included antibodies from Abcam (London, England), Oil red O stain from Solarbio Science & Technology Co., Ltd. (Beijing, China) and Cell culture flasks and transwell plates from Corning (New York, USA).
9
Curcumin Extraction and Purification
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Curcumin was obtained from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Tween 80 was purchased from Yibei Chemical Reagent (Tianjin, China). Methanol and ethanol were both provided by Beichen Founder Reagent Plant (Tianjin, China). Acetonitrile was obtained from Kermel Chemical Reagent Co., Ltd. (Tianjin, China). Sodium dodecyl sulphate was purchased from Tianjin Baodi Chemical Holding Co., Ltd. (Tianjin, China). Acetic acid glacial was purchased from Fuchen Chemical Reagent (Tianjin, China). All other chemicals were of analytical grade. Distilled water was used throughout the study.
10
Detailed Protocol for Casein-Curcumin Extraction
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Casein (CAS#: 9000-71-9) was purchased from Hefei Bomei Biotechnology Co., Ltd., Room 901, Office B-Xinghua International Plaza, No. 50, Hetang Road, Luyang District, Hefei, China. Curcumin (CAS#: 458-37-7, purity ≥ 95%) was obtained from Sinopharm Chemical Reagent Co., Ltd., No. 52, Ningbo Road, Shanghai, China. Absolute ethanol (CAS#: 64-17-5) and hydrochloric acid (CAS#: 7647-01-0) were purchased from Chongqing Chuandong Chemical (Group) Co., Ltd., No. 70, Danzishi New Street, Danzishi Street, Nan’an District, Chongqing, China. Tris (CAS#: 77-86-1) was supplied from Saiguo Biotech Co., Ltd., No. 1, Eighth Alley, Zhangmu Mountain, Cen Village, Guangzhou, Tianhe District, Guangzhou, China. All reagents used in the experiments were analytical grade, and ultrapure water was used for the experiments.
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