RXB was acquired from Hanmi Pharm. Co. (Suwon, Korea). HPMC 645 (4.5 cps) and PVA were purchased from Shin-Etsu. Co. (Tokyo, Japan). Gelatin and sodium alginate (Na-alginate) were obtained from Daejung Chemical Co. (Siheung, Korea). Hydroxypropyl-β-cyclodextrin (HP-β-CD) and β-cyclodextrin (β-CD) were purchased from Roquette (Lestrem, France). All other organic solvents used were of high-performance liquid chromatography (HPLC) grade.
Hydroxypropyl β cyclodextrin hp β cd
Manufactured by Roquette
Sourced in France
Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide derivative used as a pharmaceutical excipient. It is formed by the hydroxypropylation of β-cyclodextrin, a naturally occurring carbohydrate. HP-β-CD is a water-soluble, non-toxic, and non-immunogenic compound.
Automatically generated - may contain errors
Lab products found in correlation
Gelatin, by Daejung Chemicals (1 mentions)
Cholesteryl hemisuccinate, by Merck Group (1 mentions)
1 2 dipalmitoyl sn glycero 3 phosphocholine, by Merck Group (1 mentions)
L α phosphatidylcholine from, by Merck Group (1 mentions)
Sodium chloride (nacl), by Avantor (1 mentions)
Methanol meoh, by Avantor (1 mentions)
Calcium chloride, by Honeywell (1 mentions)
Ethanol, by Merck Group (1 mentions)
Sucrose, by Merck Group (1 mentions)
Acetone, by Merck Group (1 mentions)
Mannitol, by Merck Group (1 mentions)
Trehalose, by Merck Group (1 mentions)
Digoxin, by Merck Group (1 mentions)
Citric acid monohydrate, by Avantor (1 mentions)
High performance liquid chromatography grade methanol, by Merck Group (1 mentions)
Polyethylene glycol 400 peg 400, by Merck Group (1 mentions)
Multiscreen solvinert filter plate, by Merck Group (1 mentions)
Rifampicin, by Merck Group (1 mentions)
Elacridar, by Merck Group (1 mentions)
4 protocols using hydroxypropyl β cyclodextrin hp β cd
1
Formulation and Characterization of RXB Delivery System
2
Curcumin Lipid-based Nanoformulations
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Sigma-Aldrich Co (Barcelone, Spain) supplied Curcumin (Cur), didodecyldimethylammonium bromide (DDAB), cholesterol (Cho), cholesteryl hemisuccinate (Chems), l -α-Phosphatidylcholine from egg yolk (EPC) and 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC). Hydroxypropyl)-β-cyclodextrin (HPβCD) was purchased from Roquette (Lestrem, France). Other chemicals were high-quality analytical. Solvents were HPLC quality.
3
Formulation and Characterization of Cyclodextrin-Based Intranasal Drug Delivery
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CZP was purchased from VWR International (Radnor, PA, USA). RS and RL are manufactured by Evonik Industries AG (Essen, Germany) and were kindly provided by Rofarma srl (Milan, Italy). Tween® 80 (polyoxymethylene sorbitan monooleate) (Fluka) was used as a surfactant. Ethanol, acetone, mucin (mucin from pig stomach type II), mannitol, glucose, trehalose and sucrose are Sigma-Aldrich products purchased from Merk Life Science S.r.l. (Milan, Italy). Hydroxypropyl-β-cyclodextrin (HP-β-CD) was obtained from Roquette Freres (Lestrem, France). Tetrahydrofuran (THF), acetonitrile (ACN), dimethyl sulfoxide (DMSO) and mEthanol (MeOH) were purchased from VWR International Oy (Helsinki, Finland). Triethylamine and formic acid were purchased from Fluka-Garantie. SNF was composed of sodium chloride (VWR International Oy, Helsinki, Finland), potassium chloride (Fluka Chemika, Buchs, Switzerland) and calcium chloride (Riedel-de-Haën, Seelze, Germany).
4
In Vitro Evaluation of Drug-Drug Interactions
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Rifampicin (>95% purity) and digoxin (>98% purity) were purchased from Sigma-Aldrich (Sigma-Aldrich Chemie, GmbH, Munich, Germany). Elacridar (>98% purity) was synthesized by the Discovery Chemical Synthesis department at Biocon Bristol Myers-Squibb Research and Development Center (BBRC), Bangalore, India. Polyethylene glycol 400 (PEG-400) was purchased from Sigma-Aldrich (Saint Louis, MO, USA). Citric acid monohydrate and citric acid trisodium salt dihydrate for the citrate buffer were obtained from Amresco (Solon, OH, USA). Hydroxypropyl-β cyclodextrin (HPβCD) and dimethylacetamide (DMAc) were from Roquette (Lestrem, France) and Merck (Darmstadt, Germany), respectively. MultiScreen Solvinert filter plates (0.45 µm, low-binding hydrophilic polytetrafluoroethylene) were purchased from Millipore (Carrigtwohill, Ireland). High-performance liquid chromatography–grade methanol was purchased from Merck (Mumbai, India). Formic acid was purchased from Fluka (Fluka Chemie, GmbH, Munich, Germany) and Milli-Q water from Milli-Q system (Millipore SAS, Molsheim, France). Polyethylene-50 tubing was purchased from Smiths Medical (ASD incorporation, Dublin, OH, USA), and 22-gauge needles were purchased from Becton Dickinson India Pvt Ltd (Bangalore, India).
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