Anti integrin β4 clone asc 8

Manufactured by Merck Group

Anti-integrin β4 (clone ASC-8) is a laboratory reagent used for the detection and analysis of integrin β4 in biological samples. It functions as a specific antibody that binds to and identifies the integrin β4 protein.

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Lab products found in correlation

Anti integrin α3 clone p1b5, by Merck Group (1 mentions) Anti integrin α2 clone p1e6, by Merck Group (1 mentions) Anti integrin β1 clone 6sg, by Merck Group (1 mentions)

Close spelling variants of this product

Anti-ASC (5 citations) Anti-β4 integrin (2 citations)

2 protocols using anti integrin β4 clone asc 8

Integrin-Mediated Tumor Cell Adhesion

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UMUC3 and RT112 cells were incubated for 60 min with 10 μg/mL function-blocking anti–integrin α2 (clone P1E6), anti-integrin α3 (clone P1B5), anti–integrin α6 (clone NKI-GoH3), anti-integrin β1 (clone 6SG), or anti-integrin β4 (clone ASC-8; all: MerckMillipore). Controls were incubated with cell culture medium alone. Subsequently, tumor cell adhesion to immobilized collagen as well as chemotaxis was analyzed as described above.

Juengel E., Natsheh I., Najafi R., Rutz J., Tsaur I., Haferkamp A., Chun F.K, & Blaheta R.A. (2019). Mechanisms behind Temsirolimus Resistance Causing Reactivated Growth and Invasive Behavior of Bladder Cancer Cells In Vitro. Cancers, 11(6), 777.

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Integrin-Mediated Tumor Cell Adhesion

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Tumor cells were incubated for 60 min with 10 μg/mL function-blocking anti-integrin α3 (clone P1B5), anti-integrin α5 (clone P1D6), anti-integrin αV (clone AV1), anti-integrin β1 (clone 6S6), or anti-integrin β4 (clone ASC-8) mouse mAb (all from Merck Millipore). Subsequently, tumor cell adhesion and chemotaxis were analyzed as previously described.

Justin S., Rutz J., Maxeiner S., Chun F.K., Juengel E, & Blaheta R.A. (2020). Bladder Cancer Metastasis Induced by Chronic Everolimus Application Can Be Counteracted by Sulforaphane In Vitro. International Journal of Molecular Sciences, 21(15), 5582.

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