Magnetom trio tim scanner

Manufactured by Siemens

Sourced in Germany, United Kingdom, United States

The Magnetom Trio Tim scanner is a magnetic resonance imaging (MRI) system designed for clinical use. It features a 3 Tesla superconducting magnet and a Total imaging matrix (Tim) technology, which enables advanced imaging capabilities.

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Tim Trio (1263 citations) Magnetom Trio (803 citations) Magnetom Tim Trio (616 citations) Trio scanner (467 citations) TIM Trio scanner (348 citations) Magnetom Trio scanner (69 citations) Magnetom scanner (56 citations) Siemens scanners (11 citations) TrioTM (3 citations) Magnetom Trio Tim 3.0T scanner (3 citations)

83 protocols using magnetom trio tim scanner

Neuroimaging Protocol for Brain Imaging

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Participants were scanned at the Clinical Imaging Research Centre, National University of Singapore, on a 3 T Siemens Magnetom Tim Trio scanner using a 32-channel head coil. The scan protocol included a T₁-weighted MPRAGE (magnetization prepared rapid gradient recalled echo) sequence (repetition time = 2300 ms, echo time = 1.9 ms, inversion time = 900 ms, flip angle = 9°, 192 sagittal slices, matrix size = 256 × 256, voxel size = 1.0 × 1.0 × 1.0 mm³), a FLAIR (fluid attenuated inversion recovery) sequence (repetition time = 9000 ms, echo time = 82 ms, inversion time = 2500 ms, flip angle = 180°, 48 transversal slices, matrix size = 256 × 232, voxel size = 1.0 × 1.0 × 3.0 mm³), and a 5-min T₂*-weighted task-free functional MRI scan (T₂*-weighted echo planar sequence with repetition time = 2300 ms, echo time = 25 ms, flip angle = 90°, field of view = 192 × 192 mm², voxel size = 3.0 mm isotropic, slice thickness = 3 mm, 48 axial slices, interleaved collection).

Chong J.S., Liu S., Loke Y.M., Hilal S., Ikram M.K., Xu X., Tan B.Y., Venketasubramanian N., Chen C.L, & Zhou J. (2017). Influence of cerebrovascular disease on brain networks in prodromal and clinical Alzheimer’s disease. Brain, 140(11), 3012-3022.

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Multimodal Neuroimaging Acquisition Protocol

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Structural MRI and diffusion-weighted images (DWI) were acquired on a 3T Siemens Magnetom Tim Trio scanner (Siemens Medical Solutions, Erlangen, Germany). The high-resolution structural scan consisted of an ultrafast gradient echo 3D sequence (MPRAGE) with PAT k-space-based algorithm GRAPPA. The parameters were: echo time = 3.31 ms; repetition time = 2530 ms; matrix size = 256 × 256; field of view (FOV) = 256 mm; slice thickness = 1 mm. The DWI sequence acquired 64 transverse slices with no gaps and 2.0 mm nominal isotropic resolution (TR/TE = 8600/93 ms, FOV = 244 × 244, data matrix = 96 × 96, zero-filled and reconstructed to 256 × 256). Diffusion weighting was performed along 64 directions with a b value = 900 s/mm². One non-diffusion weighted volume (b₀) was acquired within each DWI dataset. A high resolution T2 scan was also obtained to allow for enhanced registration of structural MR images to DWIs.

Kikinis Z., Makris N., Sydnor V.J., Bouix S., Pasternak O., Coman I.L., Antshel K.M., Fremont W., Kubicki M.R., Shenton M.E., Kates W.R, & Rathi Y. (2018). Abnormalities in gray matter microstructure in young adults with 22q11.2 deletion syndrome. NeuroImage : Clinical, 21, 101611.

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Whole Brain Functional Imaging Protocol

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Whole head echo‐planar images (EPI) were collected on a 3.0‐Telsa Siemens Magnetom Tim Trio scanner at the Center for Functional and Molecular Imaging at Georgetown University Medical Center with the following parameters: TR of 3,000 ms, TE of 30 ms, 64 × 64 matrix, 192 mm FOV, flip angle = 90°, 50 axial slices collected in a descending sequence, 3.0 × 3.0 × 2.8 mm voxels with a 0.2 mm gap. For each functional run, 89 full 3D brain volumes were collected. High‐resolution T1‐weighted structural brain images were also collected, for the purpose of coregistering the functional images.

Brignoni‐Pérez E., Matejko A.A., Jamal N.I, & Eden G.F. (2021). Functional neuroanatomy of arithmetic in monolingual and bilingual adults and children. Human Brain Mapping, 42(15), 4880-4895.

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Optimized fMRI Acquisition for Prefrontal Cortex

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fMRI imaging was conducted in a 3T Siemens MAGNETOM Tim/Trio scanner in the Dana and David Dornsife Cognitive Neuroscience Imaging Center at the University of Southern California. Functional scanning used a z-shim gradient echo EPI sequence with PACE (Prospective Acquisition Correction). This specific sequence is dedicated to reduce signal loss in the prefrontal and orbitofrontal areas. The PACE option can help reduce the impact of head motion during data acquisition. The parameters are: TR/TE=2000/25 ms; flip angle = 90°; 64×64 matrix size with resolution 2×2×2 mm³. Thirty-one 3.5-mm axial slices were used to cover the whole cerebral cortex and most of the cerebellum with no gap. The slices were tilted about 30° clockwise along the AC–PC plane to obtain better signals in the orbitofrontal cortex. The anatomical T1-weighted structural scan was done using an MPRAGE sequence (TR/TE/TI=2530/3.1/800 ms; flip angle 10°; 208 sagittal slices; 256×256 matrix size with spatial resolution as 1×1×1 mm³).

Brevers D., Noel X., He Q., Melrose A, & Bechara A. (2015). Increased ventral striatal activity during monetary decision-making is a marker of problem poker gambling severity. Addiction biology, 21(3), 688-699.

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Structural and Diffusion MRI Protocol

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Neuroimaging data were collected at the Oregon Health and Science University’s Advanced Imaging Research Center on a 3.0 T Siemens Magnetom Tim Trio scanner with a 12-channel head coil. Collection parameters were similar to previous research conducted by our lab (16 (link)). Briefly, a structural, high-resolution T1-weighted MP-RAGE sequence was collected (orientation = sagittal, echo time = 3.58 ms, repetition time = 2,300 ms, 256 × 256 matrix, resolution 1.0 mm × 1.0 mm × 1.1 mm). In addition, high angular resolution diffusion images were also acquired using a 72-gradient direction, whole-brain echo-planar imaging sequence (TR = 7,100 ms, TE = 112 ms, field of view = 230 mm × 230 mm, b value = 3,000 s/mm², isotropic voxel dimensions = 2.5 mm³) and 10 non-diffusion-weighted images where the b value was equal to 0.

Fling B.W., Curtze C, & Horak F.B. (2018). Gait Asymmetry in People With Parkinson’s Disease Is Linked to Reduced Integrity of Callosal Sensorimotor Regions. Frontiers in Neurology, 9, 215.

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Functional Magnetic Resonance Imaging Acquisition

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Imaging was conducted on a 3T Siemens Magnetom TimTrio Scanner, equipped with a 12-channel head coil. A laptop computer running E-Prime software controlled the stimulus display that was projected (via an LCD projector) onto a screen placed at the head of the bore. Participants viewed the screen through a mirror fastened to the head coil. Cushions were used to minimize head movement and earplugs were used to dampen scanner noise. Participants made responses using a button box placed by their right hand.
Anatomical images were acquired using a high-resolution three-dimensional magnetization-prepared rapid gradient echo sequence (MPRAGE; 176 sagittal slices, echo time [TE] = 1.64 ms, repetition time [TR] = 2530 ms, flip angle = 7 degrees, voxel size = 1 x 1 x 1 mm). Functional images (340 scans including simulation cues) were collected using a T2* gradient echo, echo-planar imaging (EPI) sequence sensitive to blood oxygen level-dependent (BOLD) contrast (TR = 2500 ms, TE = 30 ms, flip angle = 90 degrees, 3 x 3-mm in-plane resolution). Whole-brain coverage was obtained with 39 contiguous slices, acquired parallel to the anterior-posterior commissure plane (3-mm slice thickness, 0.5-mm skip between slices).

Szpunar K.K., Jing H.G., Benoit R.G, & Schacter D.L. (2015). Repetition-Related Reductions in Neural Activity during Emotional Simulations of Future Events. PLoS ONE, 10(9), e0138354.

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fMRI Acquisition and Analysis Protocol

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During fMRI scanning, we obtained the response accuracy (i.e., correct versus incorrect response) and the reaction time (RT) for each trial. Anatomical and functional brain data were acquired with a whole-body 3-T Magnetom TIM TRIO scanner (Siemens Healthcare, Erlangen, Germany) with a 12-channel head coil. Functional data were acquired with a gradient-echo EPI sequence (repetition time (TR) = 2 s; echo time (TE) = 30 ms; flip angle = 90°; 26 slices; data matrix = 64 × 64 voxels; voxel size = 3 × 3 × 3 mm³; 1 mm gap; field of view (FOV) = 192 mm; 484 volumes). Structural data were obtained with a T1-weighted magnetization-prepared rapid gradient-echo 3D sequence with selective water excitation and linear phase encoding. The magnetization preparation consisted of a non-selective inversion pulse. To avoid aliasing, oversampling was performed in the read direction (inversion time = 740 ms; TR = 1480 ms; TR of the gradient-echo kernel (snapshot FLASH) = 10 ms; TE = 3.46 ms; flip angle = 10°; data matrix = 256 × 240 voxels; voxel size = 1 × 1 × 1.5 mm³; FOV = 256 × 240 mm²; 128 partitions; slab thickness = 192 mm).

Fengler A., Meyer L, & Friederici A.D. (2016). How the brain attunes to sentence processing: Relating behavior, structure, and function. Neuroimage, 129, 268-278.

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Structural and Functional MRI Acquisition

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All MRIs were acquired at Athinoula A. Martinos Imaging Center at MIT on a 3T Siemens Magnetom Tim Trio scanner. Structural MRI was obtained using an MP-RAGE sequence producing T1-weighted images (echo time = 1.64 msec, repetition time [TR] = 2530 msec, flip angle = 7°, 176 slices with 1 × 1 × 1 mm isometric voxels) using a 32-channel head coil. To reduce the imaging acquisition time, parallel imaging was used with an acceleration factor of 3. BOLD signal was obtained using a gradient-echo T2*-weighted EPI sequence (echo time = 30 msec, TR = 2000 msec, flip angle = 90°, bandwidth = 2300, echo spacing = 0.5, field of view = 192 × 192, matrix size = 64 × 64, resulting in in-plane resolution of 3 mm × 3 mm). Thirty-two 3-mm-thick slices were acquired positioned parallel to the AC–PC line using noninterleaved acquisition. Before each scan, four images were acquired and discarded to allow longitudinal magnetization to reach equilibrium. PACE, an on-line prospective motion correction algorithm, was included to reduce the effect of motion artifacts.

Sheridan M., Kharitonova M., Martin R.E., Chatterjee A, & Gabrieli J.D. (2014). Neural Substrates of the Development of Cognitive Control in Children Ages 5–10 Years. Journal of cognitive neuroscience, 26(8), 1840-1850.

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Structural and Diffusion Imaging Protocol

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Image acquisition and analysis for this cohort have previously been described.^{16 (link)} Briefly, images were acquired using a 3.0 T Siemens Magnetom Tim Trio scanner with a 12-channel head-coil at the OHSU’s Advanced Imaging Research Center. One whole-brain high-resolution structural T1-weighted Magnetization Prepared Rapid Gradient Echo (MPRAGE) sequence (orientation=sagittal, echo time (TE)=3.58 ms, repetition time (TR)=2300 ms, 256×256 matrix, resolution=1 mm³) was collected. Three sets of diffusion-weighted images were collected using a 30-gradient direction, whole-brain echoplanar imaging sequence (TR=9100 ms, TE=88 ms, field of view=240 mm², b value=1000 s/mm², isotropic voxel dimensions=2 mm³) and three images in which the b value was equal to zero. A static magnetic field map was also acquired using the same parameters as the DTI sequence. Standard diffusion image processing was followed using tools implemented in FMRIB Software Library (FSL; V.4.1.9; http://www.fmrib.ox.ac.uk/fslwww.fmrib.ox.ac.uk/fsl), including correction for eddy current distortions and motion artefacts, averaged to improve signal-to-noise ratio and subsequently skull-stripped using FSL’s brain extraction tool.

Peterson D.S., Fling B.W., Mancini M., Cohen R.G., Nutt J.G, & Horak F.B. (2014). Dual-task interference and brain structural connectivity in people with Parkinson’s disease who freeze. Journal of neurology, neurosurgery, and psychiatry, 86(7), 786-792.

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High-Resolution T1-Weighted Brain Imaging

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Participants underwent MRI imaging acquired at the Wolfson Brain Imaging Centre (University of Cambridge) on a 3T Siemens Magnetom Tim Trio scanner. A T1-weighted magnetization-prepared rapid gradient echo (MPRAGE) sequence was acquired with the following parameters: relaxation time (TR) = 2300 ms, echo time (TE) = 2.98 ms, field of view = 240 × 256 mm², 176 slices, flip angle = 9°, isotropic 1mm³ voxel.

Nicastro N., Mak E., Surendranathan A., Rittman T., Rowe J.B, & O’Brien J.T. (2021). Altered structural connectivity networks in dementia with lewy bodies. Brain Imaging and Behavior, 15(5), 2445-2453.

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