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Chloroauric acid tetrahydrate

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Chloroauric acid tetrahydrate is a chemical compound used in various laboratory applications. It is a crystalline solid that contains gold in the trivalent oxidation state. The compound serves as a precursor for the synthesis of other gold compounds and is used in processes such as electroplating and nanoparticle synthesis.

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Lab products found in correlation

Silver nitrate, by Merck Group (4 mentions) Ascorbic acid, by Merck Group (3 mentions) Sodium borohydride, by Merck Group (2 mentions) L ascorbic acid, by Merck Group (2 mentions) Diethyl ether, by Merck Group (2 mentions) Sodium hydroxide (naoh), by Merck Group (1 mentions) Ammonium hydroxide solution, by Merck Group (1 mentions) Hydroxylamine, by Merck Group (1 mentions) Potassium carbonate, by Merck Group (1 mentions) Sodium citrate, by Merck Group (1 mentions) Dimethylformamide, by Merck Group (1 mentions) Pentafluorophenyl, by Merck Group (1 mentions) Cetrimonium bromide, by Merck Group (1 mentions) 16 mercaptohexadecanoic acid, by Merck Group (1 mentions) N diisopropylethylamine, by Merck Group (1 mentions) N cyclohexyl n 2 morpholinoethyl carbodiimide metho p toluenesulfonate cmc, by Merck Group (1 mentions) Trisodium citrate dehydrate, by Merck Group (1 mentions) Bovine serum albumin (bsa), by Merck Group (1 mentions) Water purification system, by Merck Group (1 mentions) Chloroplatinic acid hexahydrate, by Merck Group (1 mentions)

Close spelling variants of this product

Chloroauric acid (151 citations) Chloroauric acid tetrahydrate HAuCl4 4H2O (2 citations)

10 protocols using chloroauric acid tetrahydrate

1

Synthesis of Gold Nanoparticles

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Tetraethylorthosilicate (TEOS), tetrakis (hydroxymethyl) phosphonium chloride (THPC), 3-aminopropyltrimethoxysilane (APTMS), sodium hydroxide, hydroxylamine (50% in H2O), potassium carbonate and chloroauric acid tetrahydrate (HAuCl4.4H2O) were obtained from Sigma-Aldrich. Ammonium hydroxide solution (30%) was purchased from Merck Company. All the reagents were analytical grade and used as received.
Woodard L.E., Dennis C.L., Borchers J.A., Attaluri A., Velarde E., Dawidczyk C., Searson P.C., Pomper M.G, & Ivkov R. (2018). Nanoparticle architecture preserves magnetic properties during coating to enable robust multi-modal functionality. Scientific Reports, 8, 12706.
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2

Synthesis of Gold Nanoparticles

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Cetrimonium bromide (CTAB), chloroauric acid tetrahydrate (HAuCl4), silver nitrate (AgNO3), sodium borohydride (NaBH4), sodium citrate (Na3C6H5O7), L-ascorbic acid (C6H8O6), 16—mercaptohexadecanoic acid (MHDA), dimethylformamide (DMF), pentafluorophenyl (PFP), N, Ndiisopropylethylamine (DIPEA), N-cyclohexyl-N′-(2-morpholinoethyl) carbodiimide metho-p-toluenesulfonate (CMC) and all other chemicals were purchased from Sigma–Aldrich (Darmstadt, Germany).
Depciuch J., Miszczyk J., Maximenko A., Zielinski P.M., Rawojć K., Panek A., Olko P, & Parlinska-Wojtan M. (2020). Gold Nanopeanuts as Prospective Support for Cisplatin in Glioblastoma Nano-Chemo-Radiotherapy. International Journal of Molecular Sciences, 21(23), 9082.
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3

Oligonucleotide Probe Synthesis and Purification

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Chloroauric acid tetrahydrate (HAuCl4.4H2O) and trisodium citrate dehydrate were purchased from Sigma and used as received. Other chemicals were of analytical grade and were used without further purification. All oligonucleotides were synthesized and purified with PAGE by BioNEER (Nedayfan co. Iran). The Right and Left probes were chemically thiolated at 5′ site (Right: 5′R) and 3′ site (Left: 3′L) respectively. The sequences and description of all types of oligonucleotides included in our assay were listed in Table 1.
Shokri E., Hosseini M., Davari M.D., Ganjali M.R., Peppelenbosch M.P, & Rezaee F. (2017). Disulfide-induced self-assembled targets: A novel strategy for the label free colorimetric detection of DNAs/RNAs via unmodified gold nanoparticles. Scientific Reports, 7, 45837.
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4

Synthesis and Characterization of Nanocomposites

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Chloroplatinic acid hexahydrate (H2PtCl6·6H2O), chloroauric acid tetrahydrate (HAuCl4·4H2O) and bovine serum albumin (BSA) were obtained from Sigma‒Aldrich Chemical Co. (St. Louis, MO, USA). Graphite powder (< 45 mm), NaNO3, H2SO4 and KMnO4 were supplied by Guoyao Group Chemical Reagents Co., Ltd. (Shanghai, China). All chemicals were analytical reagent grade. Double-distilled deionized water (ddH2O) prepared with a Millipore water purification system was used throughout the experiments. Phosphate-buffered saline (PBS, pH 7.0), which was prepared with 10 mmol/L NaH2PO4 and 10 mmol/L Na2HPO4 and containing 0.9% NaCl, was used as washing buffer. Electrolytes with different pH values were prepared by mixing different volumes of 10 mmol/L NaH2PO4 and 10 mmol/L Na2HPO4 and contained 0.1 mol/L KCl. Viral transport medium was prepared with PBS containing 5% (v/v) foetal bovine serum, streptomycin (10 mg/mL), kanamycin (10 mg/mL), gentamycin (10 mg/mL) and penicillin (10,000 units/mL).
Huang J., Xie Z., Li M., Luo S., Deng X., Xie L., Fan Q., Zeng T., Zhang Y., Zhang M., Wang S., Xie Z, & Li D. (2022). An Enzyme-Free Sandwich Amperometry-Type Immunosensor Based on Au/Pt Nanoparticle-Functionalized Graphene for the Rapid Detection of Avian Influenza Virus H9 Subtype. Nanoscale Research Letters, 17, 110.
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5

Aptamer-based Biosensor for Pesticide Detection

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Chloroauric acid tetrahydrate (HAuCl4·4H2O), trisodium citrate, sodium citrate dihydrate, Triton X-100, mycose, sodium dodecyl sulfonate (SDS), NaCl, Na3PO4·12H2O, Tween-20, sucrose, deoxyadenosine triphosphate (dATP), bovine serum albumin (BSA), phosphate buffered saline (PBS, pH 7.4, 0.01 M), sodium chloride-sodium citrate (SSC) buffer (20 concentrate, pH 7.0), borate buffer (BB, pH 9.0, 0.1 M), and the pesticides used in this study (chlopyrifos, malathion, diazinon, atrazine, carbaryl, acetamiprid, and 2,4-D.) were purchased from Sigma Chemical Company (St. Louis, MO, USA). Streptavidin was purchased from Invitrogen (Carlsbad, CA, USA). QDs nanobeads premodified by polystyrene maleic-anhydride copolymer were provided by Shanghai Kundao Biotech Co., Ltd. (Shanghai, China). Backing cards (HF000MC100), glass fiber sample pads (CFSP001700), conjugation pads (GFCP000800), nitrocellulose membranes (135s), and absorbent pads (CFSP001700) were purchased from Millipore (Bedford, MA, USA). Sequences of aptamers for chlorpyrifos (Jiao et al., 2017 , 2016 ), aptamers for diazinon (Jokar et al., 2017 (link)), aptamers for malathion (Bala et al., 2016 (link)) and corresponding biotinylated complementary sequences (Table S1), were synthesized and purified by Sangon Biotech Co., Ltd. (Shanghai, China). Double distilled water (ddwater) was used in all experiments.
Cheng N., Song Y., Fu Q., Du D., Luo Y., Wang Y., Xu W, & Lin Y. (2018). Aptasensor based on fluorophore-quencher nano-pair and smartphone spectrum reader for on-site quantification of multi-pesticides. Biosensors & bioelectronics, 117, 75-83.
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6

Synthesis of Arenediazonium Tosylates

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Chloroauric acid tetrahydrate (HAuCl4⋅4 H2O, 99.9 %), silver nitrate (AgNO3, 99.0 %), ascorbic acid (AA, 99.0 %), p‐toluenesulfonic acid monohydrate (98.0 %), acetic acid (≥99.7 %), tert‐butyl nitrite (90.0 %), 4‐nitroaniline (≥99 %), 4‐aminobenzoic acid (≥99 %), 4‐aminoaniline (≥99.0 %), and diethyl ether (≥99.7 %) were purchased from Sigma–Aldrich. All chemical reagents were used as received without further purification. Mueller–Hinton agar (MHA) was prepared as described by the producer (Oxoid, CM0337) and sterilized in an autoclave. Deionized water was used throughout the experiments. The corresponding arenediazonium tosylates (4‐nitrobenzenediazonium tosylate, 4‐aminobenzenediazonium tosylate, and 4‐carboxybenzenediazonium tosylate) were prepared according to the described procedure.55
Kalachyova Y., Olshtrem A., Guselnikova O.A., Postnikov P.S., Elashnikov R., Ulbrich P., Rimpelova S., Švorčík V, & Lyutakov O. (2017). Synthesis, Characterization, and Antimicrobial Activity of Near‐IR Photoactive Functionalized Gold Multibranched Nanoparticles. ChemistryOpen, 6(2), 254-260.
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7

Electrochemical Aflatoxin B1 Biosensor

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Chloroauric acid tetrahydrate (HAuCl4⋅4H2O) and ITO coated glass slides were obtained from Sigma-Aldrich (3050 Spruce St, St. Louis, MO63103, USA). An aqueous solution of Graphene oxide (1g/L, w/v) was obtained from Graphene Supermarket. Potassium chloride, sodium chloride, methanol, and ethanol were obtained from Sigma. Monosodium phosphate and disodium phosphate were obtained from Merck. Potassium ferricyanide and potassium ferrocyanide were obtained as analytical reagent grade. Aflatoxin B1 antibody was obtained from Sigma-Aldrich. All the aqueous solutions were prepared by using deionized water (DIW) (18.2 MΩ·cm) that purified by a Purite purification system. The buffer system used in this work was phosphate buffer saline (0.20 mol/L) at pH 7.4 that was prepared by dissolving disodium hydrogen phosphate (0.058 g), sodium dihydrogen phosphate (0.01015 g), sodium chloride (0.40 g) and potassium chloride (0.01 g) in 50 mL DIW and then adjusting pH to 7.4 with H3PO4 or NaOH solutions.
Althagafi I.I., Ahmed S.A, & El-Said W.A. (2019). Fabrication of gold/graphene nanostructures modified ITO electrode as highly sensitive electrochemical detection of Aflatoxin B1. PLoS ONE, 14(1), e0210652.
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8

Facile Synthesis of Functionalized Gold Nanoparticles

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Chloroauric acid tetrahydrate (HAuCl4·4H2O), ascorbic acid (AA), bovine albumin (BSA), ethanol (CH3CH2OH), N-hydroxysuccinimide (NHS), 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), 4-mercaptobenzoic acid (4-MBA), phosphate-buffered saline (PBS), trisodium citrate dihydrate (C6H5Na3O7·2H2O), silver nitrate (AgNO3) and hexadecyl trimethyl ammonium bromide (CTAB) were purchased from Sigma-Aldrich. All reagents were provided at analytical grade and were used without further purification. CYFRA21-1, rabbit monoclonal anti-CYFRA21-1, CEA、AFP, SCC-Ag were purchased Sangon Biotech Co., Ltd. Oligonucleotides (Table 1) used were obtained from Shanghai Gene Pharma Co., Ltd.
Bao X., Wang S., Liu X, & Li G. (2023). Highly sensitive detection of CYFRA21-1 with a SERS sensing platform based on the MBs enrichment strategy and antibody-DNA-mediated CHA amplification. Frontiers in Bioengineering and Biotechnology, 11, 1251595.
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9

Synthesis of Gold Nanorods

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Cetyltrimethylammonium bromide (CTAB, >98%), silver nitrate (AgNO3, >99%), L-ascorbic acid (AA, >99%), chloroauric acid tetrahydrate (HAuCl4·4H2O), n-hexane (≥95%), diethyl ether (≥98.0%), trichloro (1H,1H,2H,2H-perfluorooctyl) silane (97%), rhodamine 6G (99%), ethyl alcohol (≥99.9%), and conventional gold nanorods (aqueous dispersion, CTAB stabilizer < 0.1%) were purchased from Sigma-Aldrich (Steinheim, Germany). Sodium borohydride (NaBH4, 99%), sulfuric acid (H2SO4 98%), and hydrogen peroxide (H2O2 30%) were purchased from Merck (Darmstadt, Germany). All chemicals were used as received with no further purification. Ultrapure water (18 MΩ cm−1, EasyPure RoDi, Barnstead, UK) was used for the preparation of all aqueous solutions.
Moldovan R., Toma V., Iacob B.C., Știufiuc R.I, & Bodoki E. (2021). Off-Resonance Gold Nanobone Films at Liquid Interface for SERS Applications. Sensors (Basel, Switzerland), 22(1), 236.
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10

Synthesis of Gold Nanoparticles

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Chloroauric acid tetrahydrate (HAuCl 4 Á4H 2 O, 99.9%), silver nitrate (AgNO 3 , 99.0%), and ascorbic acid (AA, 99.0%) were purchased from Sigma-Aldrich. All chemical reagents were used as received without further purification. Deionized water was used throughout the experiments.
Kalachyova Y., Mares D., Jerabek V., Ulbrich P., Lapcak L., Svorcik V, & Lyutakov O. (2017). Ultrasensitive and reproducible SERS platform of coupled Ag grating with multibranched Au nanoparticles. Physical chemistry chemical physics : PCCP, 19(22).
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