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Pi3 kinase p110α antibody

Manufactured by Cell Signaling Technology
Sourced in United States

The PI3 kinase p110α antibody is a tool used for the detection and analysis of the p110α subunit of phosphoinositide 3-kinase (PI3K). PI3K is an enzyme that plays a crucial role in cellular signaling pathways, particularly in regulating cell growth, proliferation, and survival.

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2 protocols using pi3 kinase p110α antibody

1

Anticancer Effects of Sinularin

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In this study, sinularin was obtained from National Museum of Marine Biology & Aquarium (Pintung, Taiwan) and the chemical structure showed in Figure 1B. The anti-β-actin antibody was obtained from Sigma-Aldrich (St. Louis, MO, USA), apoptosis antibody sample kit, pro-apoptosis bcl-2 family antibody sample kit, pro-survival Bcl-2 family antibody sample kit, phospho-pI3 kinase p85 (Tyr458)/P55 (Tyr799) antibody, phosopho-GSK3β (Ser9) (D3A4) rabbit antibody, PI3 kinase p110α antibody were obtained from Cell Signaling (Danvers, MA, USA), anti-cytochrome C, CD95/Fas, AIF, phospho-Akt1, Akt1, mTOR/FRAP and phosopho-mTOR (Phospho-Ser2481) antibody were obtained from Epitomics (Bellerica, MA, USA). Goat anti-rabbit and horseradish peroxidase conjugated IgG was obtained for Millipore (Bellerica, MA, USA).
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2

V-ATPases Antibody and PPI Activation

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V-ATPases 6V1A mouse polyclonal antibody was purchased from Abnova company (Taipei City, Taiwan, P.R. China). PI3 kinase p110α antibody, Akt antibody, mTOR antibody, Phospho/TSC2(s933) antibody, Phospho/TSC2(Thr1462) antibody, phosphor(Ser/Thr) Akt substrate antibody were purchased from Cell Signaling Technology, Inc. (Danvers, MA, USA). Hamartin (TSC1), Tuberin (TSC2), HIF-1α, P-gp, MRP1, RHEB (Ras homolog enriched in brain) were purchased from Abcam PLC (Cambridge, MA, USA). Pan-toprazole (PPZ) Sodium salts (Altana Pharma AG D-78467, Wesel, Germany) and Esomeprazole Sodium for Injection (AstraZeneca PLC, Cambridge, UK) were resuspended in the RPMI-1640 (pH = 6.65, in order to activate PPIs) at 1 mg/mL immediately before use. Rapamycin was purchased from LC Laboratories (Woburn, MA, USA).
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