BALB/cJGpt-Foxn1nu/Gpt (BALB/c) female mice (4 weeks old, 12–14 g) were purchased from GemPharmatech Co., Ltd. (Nanjing, China), and housed in temperature-controlled and pathogen-free rooms. Water and food were provided freely. Huh7-Luc cells (1 × 106) that had been transfected with si-EIF4G2, si-NC (negative control), miR-144 overexpression or ctrl lentivirus were injected subcutaneously into the backs of mice near their hind legs (7 mice pergroup). The left area was the ctrl treatment, and the right area was the experimental treatment. Tumor size was measured every 2 days, and tumor volume was calculated using this formula: volume = (length × width2)/2. Mice were sacrificed after approximately 20 days by cervical dislocation. The tumors were removed and weighed and photographed. All protocols of animal studies were approved by the Institutional Animal Care and Use Committee of the First Affiliated Hospital, Zhejiang University School of Medicine.
Balb cjgpt foxn1nu gpt balb c female mice
Manufactured by GemPharmatech
Sourced in China
BALB/cJGpt-Foxn1nu/Gpt (BALB/c) female mice are an inbred strain of laboratory mice. They are characterized by the absence of a functional thymus gland, resulting in a lack of T cells and a compromised immune system.
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Lab products found in correlation
2 protocols using balb cjgpt foxn1nu gpt balb c female mice
1
Tumor Growth Inhibition by EIF4G2 Silencing
2
Huh7-Luc Xenograft Tumor Modeling
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BALB/cJGpt-Foxn1nu/Gpt (BALB/c) female mice (4 weeks old, 12-14 g) were purchased from GemPharmatech Co. Ltd (Nanjing, China), and housed in temperature-controlled and pathogen-free rooms. Water and food were provided free. Huh7-Luc cells (1 × 10 6 ) that had been transfected with si-EIF4G2, si-NC, miR-144 overexpression and ctrl lentivirus, were injected subcutaneously into back of mice near their hind legs (7 mice each group). And the left area was ctrl treatment, the right area was experimental treatment. Tumor size was measured every 2 days and tumor volume was calculated using this formula: volume= (length × width 2 )/2. Mice were sacrificed after about 20 days by cervical dislocation. And the tumors were removed and weighed and photographed. All protocols of animal studies were approved by the Institutional Animal Care and Use Committee of the First Affiliated Hospital of Zhejiang University.
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