8 m naoh

Tetracycline hydrochloride (TC), decane, calcium dichloride, magnesium dichloride, octanol, pig stomach mucin, and 8 M NaOH were purchased from Wako Pure Chemical Industries, Ltd (Osaka, Japan). OxyTetracycline hydrochloride (OTC), minocycline hydrochloride (MINO), and doxycycline hyclate (DOXY) were purchased from TCI (Tokyo, Japan). 2-Morpholinoethanesulfonic acid (MES) was purchased from Dojindo laboratories (Tokyo, Japan). Demeclocycline hydrochloride (DMCTC) and chlorTetracycline hydrochloride (CTC) were purchased from LKT Labs, Inc (MN, USA). Soybean lecithin (SLP-white) was provided by Tsuji Oil Mills co., Ltd (Mie, Japan).

Norfloxacin (NFLX), ofloxacin (OFLX), tosufloxacin tosylate monohydrate (TFLX), calcium dichloride, magnesium dichloride, iron(II) dichloride tetrahydrate, iron(III) chloride hexahydrate, aluminum(III) chloride hexahydrate, zinc chloride, lanthanum chloride heptahydrate, 1-octanol, sodium dihydrogen phosphate dihydrate, sodium chloride, sodium hydroxide, decane, 8 M NaOH, and 0.1 vol% trifluoroacetic acid-acetonitrile were purchased from Wako Pure Chemical Industries, Ltd (Osaka, Japan). Ciprofloxacin hydrochloride monohydrate (CPFX), levofloxacin (LVFX), enoxacin sesquihydrate (ENX), fleroxacin (FLRX), and prulifloxacin (PUFX) were purchased from TCI (Tokyo, Japan). Gatifloxacin (GFLX) and sparfloxacin (SPFX) were purchased from Funakoshi Co., Ltd (Tokyo, Japan). Moxifloxacin (MFLX) was purchased from Combi-Blocks Inc. (San Diego, USA). 2-Morpholinoethanesulfonic acid (MES) was purchased from Dojindo laboratories (Tokyo, Japan). 0.1 vol% trifluoroacetic acid-distilled water was purchased from Kanto chemical co., inc (Tokyo, Japan). Soybean lecithin was provided by Tsuji Oil Mills co., Ltd (Mie, Japan) (SLP-White, phosphatidylcholine (24-32 %), phosphatidylethanolamine (20-28 %), phosphatidylinositol (12-20 %), phosphatidic acid (8-15 %), and lysophosphatidylcholines (1-5 %) (based on the product information provided by the manufacturer)).