T1-weighted brain images were acquired on a 3T General Electric (Milwaukee, WI) Signa HDx MRI scanner. The structural images included 166 slices (TR = 5.7 ms, TE = 2.036 ms, FoV= 240 mm, flip angle = 12°, matrix=256mm×256mm, 166 slices, 1mm×1mm×1mm, no gap). The images were acquired as part of a larger project that also included BOLD fMRI. The BOLD fMRI results have been reported elsewhere and will not be discussed in this article (Argyropoulos, Tremblay, & Small, 2013 (link); Tremblay & Small, 2011a (link), 2011c (link)).
Signa hdx mri scanner
Manufactured by GE Healthcare
Sourced in United States
The Signa HDx MRI scanner is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It is designed to capture high-quality images of the human body to assist in medical diagnosis and treatment. The Signa HDx utilizes powerful superconducting magnets and advanced radio frequency (RF) technology to generate detailed cross-sectional images of the body's internal structures.
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4 protocols using signa hdx mri scanner
1
Structural Brain Imaging Protocol
2
Comprehensive Characterization of Magnetic Nanoparticles
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Transmission electron micrographs (TEM) were taken by TEM (JEOL JEM-2100F) for particle size determination. Infrared spectra were recorded in the range 4000–400 cm−1 on a Fourier-transform infrared spectrometer (FT-IR, Bomen Hartmann and Braun, MB series). Dynamic light scattering (DLS) measurement was determined by Zetasizer (Nano series, Malvern Instruments). The magnetic measurement was carried out using vibrating sample magnetometer (VSM, MPMS SQUIDM, USA). The absorption and emission spectra was analyzed by using a UV-vis spectroscopy (Specord 205, Jena, Germany) and fluorescence spectroscopy (Cary Eclipse, Varian, USA). The Fe concentration of the particles was determined by inductively coupled plasma analyses (ICP, Agilent 730 ICP-OES, USA). The T2 relaxation times of the particle suspension with different Fe concentrations in water were measured by a 3.0-T GE Signa HDX MRI scanner (GE, Milwaukee, USA) by using a head coil. T2-weighted images were obtained from a 4.0 mm-thick section using a 60 mm × 48 mm field of view (FOV), repetition time (TR) = 3000 ms, echo time (TE) = 40, 60, 80, 100 and 120 ms and reconstructed using a 320 × 320 image matrix. The relaxivity (r2) was calculated by a linear fitting of the inverse relaxation time as a function of the Fe concentration.
3
Early MRI for Intracerebral Hemorrhage
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As part of our clinical protocol we acquired MR images within 7 days of hemorrhage whenever deemed safe by the attending neurointensivist using a 3 T scanner (GE Signa HDx MRI scanner; HD23 software). Total acquisition time did not exceed 45 minutes. We obtained FLAIR, T1-weighted, and DWI sequences (for details please refer to the Supplementary Material).
4
Structural Brain Changes After GKRS for TN
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A total of 61 patients who was treated at Toronto Western Hospital in Canada were included in this study. Patients in this study met the following criteria: I) diagnosis of classical TN according to ICHD-3 criteria; II) GKRS treatment with no prior surgical interventions for TN; III) structural brain MRI prior to and 6 months after GKRS; IV) clinical follow-up 6 months after surgery. Patients with neurodegenerative disorders, TN secondary to multiple sclerosis, stroke, other chronic pain conditions, cranial tumors, and other neurological diseases were excluded from this study.
Images acquisition All T1-weighted images of TN patients were acquired with a 3 Tesla GE Signa HDx MRI scanner (General Electric, Boston, MA) fitted with an 8channel head coil (fast-spoiled gradient echo, TE = 5.1 ms, TR = 12.0 ms, TI 300 ms, flip angle = 20°, voxel size = 0.86 mm £ 0.86 mm £ 1.00 mm, 256 £ 256 matrix, field of view = 22 cm, 146 slices). It should be noted that TN patients scheduled for GKRS were generally scanned on the day of surgery. These images were used to guide the stereotactic surgery. However, in some cases, due to limited scanner time availability, some scans only captured subcortical regions of interest. In these cases, all subcortical regions, including the entire hippocampus, were captured, and some cortical regions were lost.
Images acquisition All T1-weighted images of TN patients were acquired with a 3 Tesla GE Signa HDx MRI scanner (General Electric, Boston, MA) fitted with an 8channel head coil (fast-spoiled gradient echo, TE = 5.1 ms, TR = 12.0 ms, TI 300 ms, flip angle = 20°, voxel size = 0.86 mm £ 0.86 mm £ 1.00 mm, 256 £ 256 matrix, field of view = 22 cm, 146 slices). It should be noted that TN patients scheduled for GKRS were generally scanned on the day of surgery. These images were used to guide the stereotactic surgery. However, in some cases, due to limited scanner time availability, some scans only captured subcortical regions of interest. In these cases, all subcortical regions, including the entire hippocampus, were captured, and some cortical regions were lost.
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