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Calcium hydrogen phosphate dihydrate

Manufactured by Merck Group
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Sourced in Germany, United States

Calcium hydrogen phosphate dihydrate is a chemical compound that is commonly used in laboratory settings. It is a white crystalline solid that is insoluble in water. The chemical formula for calcium hydrogen phosphate dihydrate is CaHPO4•2H2O. The primary function of this compound is as a source of calcium and phosphate ions in various chemical reactions and analyses.

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Lab products found in correlation

Calcium carbonate, by Merck Group (2 mentions) Calcium chloride dihydrate, by Merck Group (1 mentions) Sodium hydrogencitrate sesquihydrate, by Merck Group (1 mentions) Milli q plus, by Merck Group (1 mentions) Nitric acid, by Merck Group (1 mentions) Hydroxyapatite, by Merck Group (1 mentions) Dimethyloxalylglycine dmog, by Cayman Chemical (1 mentions) Calcium chloride, by Merck Group (1 mentions) Bovine serum albumin (bsa), by Merck Group (1 mentions) Sodium citrate tribasic dihydrate, by Merck Group (1 mentions) Gelatin, by Merck Group (1 mentions) Phosphate buffer saline (pbs), by Merck Group (1 mentions) Methylcellulose, by Merck Group (1 mentions)

4 protocols using calcium hydrogen phosphate dihydrate

1

Preparation of Inorganic Compound Solutions

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Calcium hydrogenphosphate dihydrate, sodium hydrogencitrate sesquihydrate and nitric acid were from Sigma Aldrich (Steinheim, Germany). Calcium chloride dihydrate was from Merck (Darmstadt, Germany). All aqueous solutions were made from purified water from Milli-Q Plus (Millipore Corporation, Bedford, MA).
Vavrusova M., Danielsen B.P., Garcia A.C, & Skibsted L.H. (2017). Codissolution of calcium hydrogenphosphate and sodium hydrogencitrate in water. Spontaneous supersaturation of calcium citrate increasing calcium bioavailability. Journal of Food and Drug Analysis, 26(1), 330-336.
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2

Bioactive Bone Scaffold Production

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Calcium phosphate tribasic (β-TCP, Ca3(PO4)2; 2019-1405), polyethylene glycol 6000 (PEG, H(OCH2CH2)nOH; 6554-1400), lactic acid (C3H6O3; 5057-4405), and calcium carbonate (CaCO3; 2505-4405) were purchased from DAEJUNG CHEMICALS&METALS (Siheung, Republic of Korea). Hydroxyapatite (Ca10(PO4)6(OH)2; 21223), calcium hydrogen phosphate dihydrate (DCPA, CaHPO4·2H2O; 307653), and sodium phosphate dibasic (Na2HPO4; S5136) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Hyaluronic acid ((C14H21NO11)n; 8806383168540) was purchased from Saero Hands (Seoul, Republic of Korea). Cockle shells were collected from the southern coast of the Republic of Korea.
Cho E., Kim J.E., Lee J., Park S., Lee S., Chung J.H., Kim J, & Seonwoo H. (2023). Development of 3D Printable Calcium Phosphate Cement Scaffolds with Cockle Shell Powders. Materials, 16(18), 6154.
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3

Alginate-based Biomaterial Fabrication

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Alginic acid (Alg) sodium salt from brown algae (medium viscosity), calcium chloride, calcium hydrogen phosphate dihydrate, calcium carbonate (purity ≥ 99%), bovine serum albumin (BSA, molecular weight (MW) ~66 kDa, lyophilized powder) and tetracycline (TCN, MW 444.43 Da, anhydrous basis) were purchased from Sigma Aldrich (St. Louis, MO, USA). Dimethyloxalylglycine (DMOG, MW 175.14 Da, purity ≥ 98%) was purchased from Cayman Chemical Company (Ann Arbor, MI, USA). Double distilled water (DW) was employed for experimental purposes.
Das D., Bang S., Zhang S, & Noh I. (2017). Bioactive Molecules Release and Cellular Responses of Alginate-Tricalcium Phosphate Particles Hybrid Gel. Nanomaterials, 7(11), 389.
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4

Bioactive Composite Hydrogel Formulations

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Methylcellulose (MC, viscosity 15 cps, Mw 14 kDa, DS 1.5–1.9), gelatin (from bovine skin, gel strength ~225 g Bloom, Type B), sodium citrate tribasic dihydrate (SC, C6H5Na3O7 Mw 294.10 g/mol, mp: >300 °C (lit.), pH 7.0–9.0 at 25 °C), calcium hydrogen phosphate dihydrate (DCPD, CaHPO4.2H2O, Mw 172.09 g/mol, d:2.31 g/mL), monetite (CaHPO4, Mw 136.06 g/mol), calcium carbonate (CaCO3, Mw 100.09 g/mol, d: 2.93 g, ≤30 µm particle size) and phosphate buffer saline (PBS, tablets, pH 7.4 at 25 °C) were purchased from Sigma Aldrich (Sigma Aldrich, Taufkirchen, Germany). Calcium sulfate dihydrate (CSD, CaSO4·2H2O, Mw 172.17 g/mol) was purchased from Merck (Merck KGaA, Darmstadt, Germany).
Demir Oğuz Ö, & Ege D. (2018). Rheological and Mechanical Properties of Thermoresponsive Methylcellulose/Calcium Phosphate-Based Injectable Bone Substitutes. Materials, 11(4), 604.
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