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Poly ethylene glycol diglycidyl ether

Manufactured by Merck Group
Sourced in United States

Poly(ethylene glycol) diglycidyl ether is a chemical compound used as a crosslinking agent in various laboratory applications. It is a clear, viscous liquid with an epoxy functional group at both ends of the polyethylene glycol backbone. This compound is widely used in the preparation of hydrogels, polymer networks, and other materials for research and development purposes.

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5 protocols using poly ethylene glycol diglycidyl ether

1

Enzymatic Biofuel Cell Components

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Glucose dehydrogenase (GDH; flavin adenine dinucleotide (FAD)-dependent) from Aspergillus oryzae was purchased from Toyobo Enzyme, Inc. (Japan). The glucose oxidase (GOD; FAD-dependent) from Aspergillus niger was purchased from Amano Enzyme, Inc. (Japan). The activity of the anode enzymes was certificated by the company (GDH = 584 U/mg, GOD = 243 U/mg). Bilirubin oxidase (BOD; 25 U/mg) from Myrothecium verrucaria, poly(ethylene glycol) diglycidyl ether (PEGDGE), sodium hydrosulfite, 1-vinylimidazole, acrylamide, N,N,N′,N′-tetramethyl ethylenediamine, and ammonium persulfate were purchased from Sigma-Aldrich Co. (Milwaukee, WI, USA). All other solutions including phosphate-buffered saline (PBS) were prepared using deionized Milli-Q water (DW; Millipore, Japan). PAA-PVI-[Os(dmo-bpy)2Cl]+/2+ (−0.012 V vs. Ag/AgCl) and PAA-PVI-[Os(dCl-bpy)2Cl]+/2+ (0.355 V vs. Ag/AgCl) as anode and cathode mediators were synthesized by modifying previously described methods (Fig. S2A)31 (link).
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2

Gelatin-Chitosan Hydrogel Fabrication

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Type A G (pharmaceutical grade, 280 bloom, viscosity 4.30 mPs), produced from pig skin, was purchased from Italgelatine, Italy. CH (molecular weight between 50,000 and 190,000 Da and degree of deacetylation 75%–85%) was obtained from Fluka, Italy. Poly(ethylene glycol)diglycidyl ether (molecular weight 526 Da) was supplied by Sigma-Aldrich, Italy. Ethylene diamine (EDA) and acetic acid were provided by Fluka, Italy. Dulbecco’s modified Eagle’s medium (DMEM), l-glutamine, penicillin-streptomycin, and sodium pyruvate were purchased from Sigma-Aldrich, USA. Amphotericin B and minimum essential medium (MEM) non essential amino acids solution were purchased from Gibco, ThermoFisher Scientific, USA.
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3

Polymer-based Ion-Selective Electrode Fabrication

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Tridodecylamine, potassium tetrakis(4-chlorophenyl)borate, 2-nitrophenyl octyl ether, high molecular weight poly(vinyl chloride), tris(hydroxymethyl)aminemethane (TRIS), tetrahydrofuran, poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate), and poly(ethylene glycol) diglycidyl ether were purchased from Sigma-Aldrich (St. Louis, MO, USA).
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4

Functionalization of Cellulose-based Hydrogel

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High-viscosity sodium carboxymethyl cellulose (DS = 0.9) with a molecular weight average of 700 kDa, four diglycidyl ethers (Table 1; Figure 1); glycerol diglycidyl ether (Mn 204 g/mol), poly(ethylene glycol) diglycidyl ether (Mn 500 g/mol), and poly(propylene glycol) diglycidyl ether (Mn 380 g/mol and Mn 640 g/mol), high purity D-(+)-cellobiose, and poly (ethylene glycol) Mn 400 g/mol) were purchased from Sigma-Aldrich. Sodium hydroxide (NaOH) pellets were purchased from Merck and made up into a 0.1 M solution to alkalize the CMC.
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5

Synthesis and Characterization of TNT

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2,4,6-Trinitrotoluene in acetonitrile (1 mgmL -1 ) was purchased from Supelco (Bellefonte, PA).
Potassium hydroxide (KOH) was produced by Carlo Erba (Spain), and acetone was purchased from Merck (Darmstadt, Germany). Poly vinyl alcohol (Mw 85000-124000 gmol -1 , >99% hydrolyzed) and poly ethylene glycol diglycidyl ether (EGDE, 98%) were purchased from Sigma-Aldrich Ltd.
Ultrapure water was obtained from a Barnstead EasyPure II laboratory water purification system (Barnstead EasyPure II, Thermo fisher scientific, OH).
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