Discovery 710 system

Manufactured by GE Healthcare

Sourced in United States

The Discovery 710 system is a medical imaging platform designed for Positron Emission Tomography (PET) and Computed Tomography (CT) imaging. It provides high-quality imaging capabilities for healthcare professionals.

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Lab products found in correlation

Discovery 690 pet ct system, by GE Healthcare (1 mentions) Biograph 64 system, by Siemens (1 mentions) Symbia t2 system, by Siemens (1 mentions)

Close spelling variants of this product

Discovery 710 (82 citations) Discovery 710 PET/CT system (5 citations)

4 protocols using discovery 710 system

FDG PET/CT Brain Imaging Protocol

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The patient dataset included dedicated ¹⁸F-FDG PET/CT brain scans of patients who had fasted 4 h before undergoing scanning. ¹⁸F-FDG was administered on the basis of patient weight (dose range, 14–200 MBq), 30 min before scanning. ¹⁸F-FDG PET/CT images were acquired for 15 min using a Discovery 710 system (GE Healthcare). Attenuation-corrected PET images were iteratively reconstructed by standard vendor-provided software, using a voxel size of 2 × 2 × 3.27 mm.
The control dataset comprised whole-body ¹⁸F-FDG PET/CT scans of patients referred for oncology staging but displaying no brain pathology (pseudocontrols) (10 (link)). We considered only the brain sections of these scans. ¹⁸F-FDG PET/CT scanning of these data was performed using a Discovery 690 PET/CT system (GE Healthcare) at multiple bed positions in 3-dimensional mode for 3–5 min per bed position (10 (link)). Attenuation-corrected PET images were iteratively reconstructed by standard vendor-provided software, using a voxel size of 3.65 × 3.65 × 3.27 mm. A complete description of the acquisition protocol and parameters was previously published (10 (link)).

De Blasi B., Barnes A., Galazzo I.B., Hua C.H., Shulkin B., Koepp M, & Tisdall M. (2018). Age-Specific 18F-FDG Image Processing Pipelines and Analysis Are Essential for Individual Mapping of Seizure Foci in Pediatric Patients with Intractable Epilepsy. Journal of Nuclear Medicine, 59(10), 1590-1596.

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Quantifying Respiratory Blur in PET/CT

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Thirty consecutive PET/CT, different from those used for threshold determination, were retrospectively selected. All were acquired on a Discovery 710 system (General Electrics, Milwaukee, WI) after an intravenous injection of 3 MBq/kg of 18F-FDG. An external observer was asked to rate the respiratory blur from 1 (absent) to 5 (major blur). Correlation between perceptual blur and blur index were computed using Pearson correlation coefficient on R software.^{[9 ]}

Morland D., Lalire P., Guendouzen S., Papathanassiou D, & Passat N. (2019). A no-reference respiratory blur estimation index in nuclear medicine for image quality assessment. Medicine, 98(48), e18207.

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PET/CT Protocol for 2-[18F]FDG Imaging

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After patients had fasted for at least 6 hours, their blood glucose levels were confirmed to be lower than 11.1 mmol/L before 2-[¹⁸F]FDG (3.5–4.5 MBq/kg) was administered. Sixty minutes after the injection, all patients underwent 2-[¹⁸F]FDG PET/CT performed with the Discovery 710 system (GE HealthCare, Chicago, IL, USA) or the Biograph 64 system (Siemens Healthineers, Erlangen, Germany). Whole-body CT images were obtained for attenuation correction using automatic dose modulation under the following settings: voltage, 120–140 kV; current, 100 mAs; rotation, 0.8; slice thickness, 3–5 mm; and pitch, 1 (19 (link)). Whole-body PET scans were obtained from the base of the skull to the upper femur in the free-breathing mode. The parameters of PET were three-dimensional mode, 2–2.5 min/bed (30% overlap), 4–5 beds/person, 3 iterations, 21 subsets, and a Gaussian filter half-height width of 4.0 mm.

Li C., Dong Y., Pan Y., Han Y., Zhang J., Luan X., Liu J., Xu X., Guan Z., Wang G, & Xu B. (2024). Metabolic parameters of pretreatment 2-[18F]fluoro-D-glucose positron emission tomography for prognosis in patients with gallbladder adenocarcinoma: a cohort study. Quantitative Imaging in Medicine and Surgery, 14(1), 604-617.

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Gamma-Camera and PET Acquisition Protocols

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For gamma-camera acquisitions, 200 images of 1 second were acquired in planar mode on a 128 × 128 matrix using a Symbia T2 system (Siemens Medical Solutions, USA). For PET acquisitions, a 200 second volume was acquired in list-mode on a Discovery 710 system (General Electrics, Milwaukee, WI) and reconstructed to obtain 200 frames of 1 second (OSEM: 24 subsets and 2 iterations, no attenuation correction, reconstructed slice thickness of 3.27 mm, Butterworth post-filter with 6.4 mm cut-off).
Random blurred images were obtained by summing 40 randomly selected frames in the 200 frames available in each acquisition. Thirty datasets of 4 random blurred images were reconstructed for gamma-camera acquisition and another 30 datasets for PET acquisition.

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