Carfilzomib (free base, >99%) was purchased from LC Laboratories (Woburn, MA). Poly(ethylene glycol)-block-poly(L-glutamic acid sodium salt) with 5 kDa PEG and 100 repeating units of glutamate (PEG-PLE) was purchased from Alamanda Polymers (Huntsville, AL). Heptakis (6-deoxy-6-amino)-beta-cyclodextrin heptahydrochloride (HaβCD) was purchased from Cyclolab R&D Laboratory Ltd. (Budapest, Hungary). Citric acid was purchased from EM Science (Gibbstown, NJ). LA was purchased from Spectrum (Gardena, CA). Slide-A-Lyzer MINI Dialysis Units 20,000 MWCO and HPLC grade water were purchased from Thermo Fisher Scientific (Rockford, IL).
Slide a lyzer mini dialysis units 20 000 mwco
Manufactured by Thermo Fisher Scientific
The Slide-A-Lyzer MINI Dialysis Units 20,000 MWCO are small-volume dialysis devices designed for sample purification and buffer exchange. These units have a 20,000 molecular weight cut-off (MWCO) membrane that allows for the removal of low molecular weight compounds while retaining larger molecules of interest.
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2 protocols using slide a lyzer mini dialysis units 20 000 mwco
1
Carfilzomib Nanoparticle Formulation
2
Formulation and Characterization of Clofazimine Delivery System
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Potassium biphthalate sodium hydroxide buffer and HPLC grade water were obtained from Fisher Scientific (Fair-lawn, NJ). Slide-A-Lyzer Mini Dialysis Units (20,000 MWCO) were obtained from Thermo Scientific (Rockford, IL). Heptakis (6-amino-6-deoxy)-β-CD heptahydrochloride (CD) was purchased from Cyclolab R&D Laboratory Ltd. (Hungary). Citric acid was from EM Science (Gibbstown, NJ). CFZ was purchased from LC laboratories (Woburn, MA). Methoxy-poly(ethylene glycol)-poly(L-glutamic acid) (PEG-PLE), methoxypoly(ethylene glycol)-poly(L-lysine) (PLL) was purchased from Alamanda Polymers (Huntsville, AL). α-Ω-bis-(amino)-terminated poly(L-histidine) (PLH) was purchased from Polymer Source Inc (Canada). Linear polyethyleneimine (PEI) was purchased from Polysciences Inc (Warrington, PA).
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