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Sodium iodide

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Sodium iodide is a chemical compound used in various laboratory applications. It is a white, crystalline solid that is highly soluble in water and other polar solvents. The primary function of sodium iodide is as a scintillation detector in radiation measurement equipment, where it is used to detect and measure ionizing radiation.

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Lab products found in correlation

Hydrochloric acid (hcl), by Thermo Fisher Scientific (3 mentions) Sodium metabisulfite, by Thermo Fisher Scientific (3 mentions) Chloramine t, by Thermo Fisher Scientific (3 mentions) Formic acid, by Thermo Fisher Scientific (3 mentions) Sodium chloride (nacl), by Thermo Fisher Scientific (3 mentions) Poly bis 4 phenyl 2 4 6 trimethylphenyl amine ptaa, by Xi'an Yuri Solar Co. (3 mentions) Acetic acid, by Thermo Fisher Scientific (2 mentions) Potassium iodide, by Thermo Fisher Scientific (2 mentions) Potassium iodide, by Merck Group (2 mentions) Sodium hydroxide (naoh), by Thermo Fisher Scientific (2 mentions) Ethyl acetate, by Thermo Fisher Scientific (2 mentions) Ltq orbitrap velos mass spectrometer, by Thermo Fisher Scientific (2 mentions) 1 4 dibromobutane, by Oakwood Chemical (2 mentions) Sodium bromide, by Thermo Fisher Scientific (2 mentions) Glacial acetic acid, by Thermo Fisher Scientific (2 mentions) N n dimethylformamide (dmf), by Thermo Fisher Scientific (2 mentions) Bovine ubiquitin, by Merck Group (1 mentions) Mercuric chloride, by Merck Group (1 mentions) Sulfuric acid, by Thermo Fisher Scientific (1 mentions) Potassium permanganate, by Thermo Fisher Scientific (1 mentions)

21 protocols using sodium iodide

1

Synthetic Peptide Substrate Preparation

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A synthetic peptide with amino acid sequence RGYALG (residues 21–26 of chicken lysozyme and a synthetic peptide substrate for a cyclic-AMP dependent protein kinase[28 (link)] was purchased from American Peptide Company (Sunnyvale, CA, USA). Sodium iodide, chloramine-T, sodium metabisulfite and other organic solvents were purchased from Thermo Fisher Scientific (Waltham, MA USA). Bovine ubiquitin was purchased from Sigma-Aldrich (St. Louis, MO, USA).
Zhang X., Li H., Moore B., Wongkongkathep P., Ogorzalek Loo R.R., Loo J.A, & Julian R.R. (2014). Radical directed dissociation of peptides and proteins by IRMPD and SORI-CID with FTICR mass spectrometry. Rapid communications in mass spectrometry : RCM, 28(24), 2729-2734.
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2

Nitrate-Based Oxidative Assays

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Sodium nitrate (NaNO3), sulfuric acid (H2SO4 – 95.0–98.0%), potassium permanganate (KMnO4), hydrogen peroxide (H2O2 – 30 wt%), hydrochloric acid (HCl – 36 wt%), sodium iodide, potassium iodide, iodine, acetic acid (99.5%), sulfanilamide, and MTT assay were purchased from Thermo Scientific, Fisher Scientific, Acros, Nacalai Tesque and Alfa Aesar, respectively. Graphite flakes, N-(3-dimethylaminopropyl-N′-ethylcarbodiimide) hydrochloride (EDC), N-hydroxysuccinimide (NHS), phosphate buffered saline (PBS), potassium bromide (KBr), sodium nitrite (NaNO2 – 97%), potassium iodide, vanadium chloride, TEM copper grid, cysteamine, S-nitroso-N-acetyl-dl-penicillamine (SNAP), diethyldithiocarbamic acid sodium salt (DETC), iron (II) sulfate heptahydrate (FeSO4·7H2O, ≥99%), dichloromethane (CH2Cl2), mercuric chloride (HgCl2), 1 M hydrochloric acid (HCl) and the LDH assay kit (coulorimetric, MAK066) were purchased from Sigma Merck. ATCC medium containing 4 mM l-glutamine, 4500 mg/L glucose, 1 mM sodium pyruvate, and 1500 mg/L sodium bicarbonate was purchased from LGC Limited, UK. cGMP ELISA kits were purchased from Enzo Life Science, UK. BrdU cell proliferation assay kits were purchased from Cell Signalling Technology, UK. DAF-FM DA was purchased from Abcam, UK. All materials were used as received without any further purification unless stated otherwise.
Tabish T.A., Hussain M.Z., Zervou S., Myers W.K., Tu W., Xu J., Beer I., Huang W.E., Chandrawati R., Crabtree M.J., Winyard P.G, & Lygate C.A. (2024). S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications. Redox Biology, 72, 103144.
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3

Synthesis and Characterization of Compound 1

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All materials received were used without any further purification unless otherwise specified. Triethanol amine, dimethyl formamide, methyl thioglycolate, thionyl chloride, chloroform, copper(II) chloride dihydrate, and potassium carbonate were purchased from Sigma Aldrich. Phosphoryl chloride, sodium iodide, nickel(II) chloride hexahydrate, cobalt(II) chloride hexahydrate, zinc(II) chloride, and ferrous ammonium sulfate hexahydrate (Fe(NH4)2(SO4)2) were purchased from Fischer Scientific. All deuterated solvents were purchased from Cambridge Isotope Laboratories. Compound 1 was prepared following a reported procedure.22 ,23 (link)
Gasol J.M., Zweifel U.L., Peters F., Fuhrman J.A, & Hagström Å. (1999). Significance of Size and Nucleic Acid Content Heterogeneity as Measured by Flow Cytometry in Natural Planktonic Bacteria. Applied and Environmental Microbiology, 65(10), 4475-4483.
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4

Phenolic Standards Characterization

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The phenolic standards comprising p-hydroxybenzaldehyde, protocatechuic aldehyde, 2,4-dihydroxybenzoic acid, p-coumaric acid, ferulic acid, catechin, quercetin and naringenin, as well as the chemicals 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and fluorescein disodium salt, were acquired from Sigma-Aldrich Chemical Co. (St. Louis, MO, USA). Liquid chromatography-mass spectrometry (LCMS)-grade methanol, acetic acid, formic acid, LCMS-grade acetonitrile, Folin-Ciocalteu phenol reagent, hydrochloric acid, sodium hydroxide, dipotassium hydrogen phosphate, potassium dihydrogen phosphate, sodium carbonate, sodium iodide, ethyl acetate, and acetone were procured from Thermo Fisher Scientific (West Palm Beach, FL, USA).
Apea-Bah F.B., Li X, & Beta T. (2021). Phenolic Composition and Antioxidant Properties of Cooked Rice Dyed with Sorghum-Leaf Bio-Colorants. Foods, 10(9), 2058.
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5

Synthesis and Characterization of Dibrominated Compounds

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The chemicals and solvents were purchased from Sigma Aldrich (St. Louis, MO, USA), except for the following: resorcinol and 4-bromophenylacetic acid obtained from Acros Organic (Carlsbad, CA, USA), 1,4-dibromobutane obtained from Oakwood Chemical (Estill, SC, USA), 1,8-dibromooctane obtained from Rhawn (Shanghai, China), sodium iodide obtained from Fisher Scientific (Waltham, MA, USA), and piperazine and 1-(2-hydroxyethyl)piperazine obtained from (J&K Scientific (Shijiazhuang, Hebei, China).
The nuclear magnetic resonance spectra were measured in CDCl3 or DMSO-d6 using Bruker instruments (1H, 600; 13C, 151Mz; Bruker, Inc., Billerica, MA, USA). The LTQ-Orbitrap Velos mass spectrometer was utilized to acquire the high-resolution electrospray ionization (ESI) mass spectra (Thermo Fisher Scientific, Waltham, MA, USA). The FT resolution was set at 100,000 (at 400 m/z). The samples were introduced by means of direct infusion utilizing a syringe pump operating at a flow rate of 5 µL/min.
DBI-1 and DBI-2 were synthesized using the methods described previously [22 (link)] and fully characterized according to standard conventions (Supplementary Materials File S1).
Guo L., Zhang B., Zhang W., Xie Y., Chen X., Sun X., Watt D.S., Liu C., Spielmann H.P, & Liu X. (2024). Inhibition of Carbohydrate Metabolism Potentiated by the Therapeutic Effects of Oxidative Phosphorylation Inhibitors in Colon Cancer Cells. Cancers, 16(7), 1399.
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6

Diverse Peptide Synthesis and Characterization

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Peptides RKRRQtSM, RQSVELHsPQSLPR, RGDC, RPHERNGFTVLCPKN, HCLGKWLGHPDKF, NTWTTCQSIAFPSK, and SHLVEALYLVCGERG were purchased from Anaspec (San Jose, CA). SLRRSSCFGGR and CQDSETRTFY were purchased from Abbiotec (San Diego, CA). CDPGYIGSR was purchased from Apexbio, and CGYGPKKKRKVGG was purchased from American Peptide Company (Sunnyvale, CA). GSNKGAIIGLM (Piscataway, NJ) was purchased from GenScript. DRVYIHPF was purchased from Sigma-Aldrich (St. Louis, MO). Naphthoquinone (NQ), iodoacetamide and dimethyl sulfoxide (DMSO) were purchased from Sigma-Aldrich (St. Louis, MO). Benzoquinone (BQ), benzyl mercaptan (BM), and trifluoroacetic acid (TFA) were purchased from Alfa Aesar (Haverhill, MA). Naphthalenethiol (NT) was purchased from Fluka Analytical (Mexico City, Mexico). Iodomethane was purchased from Arcos Organics (Geel, Belgium). Chloramine-T, sodium metabisulfite, and sodium iodide were purchased from Fisher Chemical (Fairlawn, NJ). Acetonitrile (ACN) and methanol were purchased from Fisher Scientific (Waltham, MA). Water was purified by Millipore Direct-Q (Millipore, Billerica, MA). A Macrotrap holder and Macrotrap consisting of polymeric reversed-phase packing material were purchased from Michrom Bioresources, Inc (Auburn, CA).
Talbert L.E, & Julian R.R. (2018). Directed-Backbone Dissociation following Bond-Specific Carbon-Sulfur UVPD at 213 nm. Journal of the American Society for Mass Spectrometry, 29(9), 1760-1767.
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7

Reagents for Biochemical Studies

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Sodium chloride, sodium bromide, sodium iodide, sodium thiosulfate, sodium acetate, lithium chloride, potassium chloride, cesium chloride and ammonium chloride were purchased from Fisher Scientific; 1,2-hexanediol, pyrene, benzoylacetone and ANS (8-anilinonaphthalene-1-sulfonic acid) were purchased from Sigma Aldrich; lyophilized Ribonuclease A (RNase A) prepared from bovine pancreas and RNA from yeast were purchased from Worthington Biochemical Corporation.
Francisco O.A., Clark C.J., Glor H.M, & Khajehpour M. (2019). Do soft anions promote protein denaturation through binding interactions? A case study using ribonuclease A. RSC Advances, 9(6), 3416-3428.
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8

Measurement of Nitrite Levels in Cells

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Nitrite accumulation was measured as a marker of NO production using a Sievers 280i nitric oxide analyser (NOA). NGPC and HGPC were seeded in triplicate in a 96-well plate at 2 × 104 cells/well and treated with NG, IG or HG medium for 48 h under standard conditions. The eNOS-inhibitor, Nω-nitro-l-arginine methyl ester (l-NAME; 100 µM for 24 h) and calcium ionophore A23187 (1 µM for 1 min) were used as negative and positive controls respectively, to confirm the role of eNOS in the nitrite measured. The medium from each triplicate was collected into a single tube and stored at – 80 °C for batch measurement. Test samples were defrosted on ice, diluted 1 in 4 in deionized water and 100 µl injected into the NOA chamber containing 4.5 ml of glacial acetic acid (Fisher Scientific), 100 µl of diluted antifoam B emulsion and 0.5 ml of sodium iodide (25 mg/ml; Fisher Scientific). Data were acquired using Liquid Software (version 2), integrated and then sample nitrite values extrapolated from the standard curve.
Fiorello M.L., Treweeke A.T., Macfarlane D.P, & Megson I.L. (2020). The impact of glucose exposure on bioenergetics and function in a cultured endothelial cell model and the implications for cardiovascular health in diabetes. Scientific Reports, 10, 19547.
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9

Synthesis and Characterization of Novel Compounds

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Chemicals and solvents were obtained from Sigma Aldrich (St. Louis, MO, USA) with the exception of resorcinol and 4-bromophenylacetic acid (Acros Organic, Carlsbad,CA, USA), 1,4-dibromobutane (Oakwood Chemical, Estill, SC, USA), sodium iodide (Fisher Scientific, Waltham, MA, USA), and N,N,N’-trimethyl-1,2-ethylenediamine (Toyko Chemical, Tokyo, Japan). Nuclear magnetic resonance spectra were determined in DMSO-d6 using Varian instruments (1H, 400; 13C, 100Mz; Varian, Inc., Palo Alto, CA, USA). High resolution electrospray ionization (ESI) mass spectra were recorded on a LTQ-Orbitrap Velos mass spectrometer (Thermo Fisher Scientific, Waltham, MA, USA). The FT resolution was set at 100,000 (at 400 m/z). Samples were introduced through direct infusion using a syringe pump with a flow rate of 5 μL/min. Purity was established by combustion analyses performed by Atlantic Microlabs, Inc. (Norcross, GA, USA).
Guo L., Zhang W., Xie Y., Chen X., Olmstead E.E., Lian M., Zhang B., Zaytseva Y.Y., Evers B.M., Spielmann H.P., Liu X., Watt D.S, & Liu C. (2022). Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells. Molecular cancer therapeutics, 21(5), 740-750.
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10

Synthesis and Characterization of Polymer Composite

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PVK and CEMA (97%) were purchased from Alfa Aesar Chemicals. 18-C-6 (96.0+%) and HEMA (95%) were purchased from TCI. Sodium iodide (crystalline; certified), DMF (HPLC), diethyl ether (Laboratory), ethyl acetate (certified ACS), hexanes (certified ACS), and chloroform (HPLC) were purchased from Fisher Scientific. AIBN (98%) and CPDT (97%, HPLC) were purchased from Sigma-Aldrich. 3M™ Adper™ Single Bond Plus adhesive (SB+) was purchased from 3M ESPE. HEMA was passed through a basic alumina column to remove the inhibitor prior to use. All other chemicals were used directly unless otherwise noted.
Zhang Z., Jones M.M., Sabatini C., Vanyo S.T., Yang M., Kumar A., Jiang Y., Swihart M.T., Visser M.B, & Cheng C. (2021). Synthesis and Antibacterial Activity of Polymer-Antibiotic Conjugates Incorporated into a Resin-Based Dental Adhesive. Biomaterials science, 9(6), 2043-2052.
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