Af760

Manufactured by R&D Systems

AF760 is a recombinant human Activin A protein. Activin A is a member of the transforming growth factor beta (TGF-β) superfamily and is involved in various biological processes.

Automatically generated - may contain errors

Lab products found in correlation

Ab 108 c, by R&D Systems (1 mentions) Ab 479 na, by R&D Systems (1 mentions)

2 protocols using af760

Neutralizing Antibody Effects on Glucose Tolerance

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Mice at 12 weeks of age were injected via tail veins with 45 μg neutralizing antibodies or control IgG antibodies (AB-108-C; R&D) every other day for 10 days, followed by GTT tests 2 days after the fifth (final) injection. The neutralizing antibodies used were anti-CCL2 antibodies (AB-479-NA; R&D) and anti-CCL20 antibodies (AF760; R&D).

Chuang H.C., Sheu W.H., Lin Y.T., Tsai C.Y., Yang C.Y., Cheng Y.J., Huang P.Y., Li J.P., Chiu L.L., Wang X., Xie M., Schneider M.D, & Tan T.H. (2014). HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance. Nature Communications, 5, 4602.

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Intranasal Delivery of Neutralizing Antibodies

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For neutralizing experiments (Moon et al., 2018 (link)), Dox treated IOI mice were administrated with neutralizing antibodies (NAb) or isotype IgG from day 37 for 5 consecutive days. After anesthetizing by isophorone, animals were intranasally instilled with 500 ng each of anti-CCL19 (R&D Cat# AF880) and anti-CCL20 (R&D Cat# AF760) in 5 μl sterile PBS per nostril. Control mice were treated with equal amount of isotype IgG.

Chen M., Reed R.R, & Lane A.P. (2019). Chronic inflammation directs an olfactory stem cell functional switch from neuroregeneration to immune defense. Cell stem cell, 25(4), 501-513.e5.

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