Qcl 1000 lal endpoint assay

Manufactured by Lonza

Sourced in United States

The QCL-1000™ LAL Endpoint Assay is a laboratory instrument designed to perform Limulus Amebocyte Lysate (LAL) testing. It is used to detect and quantify the presence of bacterial endotoxins in samples, which is a critical quality control measure for various industries, including pharmaceuticals and medical devices.

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QCL-1000 (65 citations) LAL assay (38 citations) LAL QCL-1000 (16 citations) LAL QCL-1000 assay (15 citations) QCL-1000 Endpoint Chromogenic LAL Assay (15 citations)

2 protocols using qcl 1000 lal endpoint assay

Serum Endotoxin Measurement by LAL Assay

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Serum endotoxin measurement was performed by a chromogenic Limulus Amebocyte Lysate (LAL) assay with a QCL-1000™ LAL Endpoint Assay (Lonza, NJ, United States) commercial analysis kit on sera previously stored at −70°C (18 (link)).

Scarpellini E., Abenavoli L., Cassano V., Rinninella E., Sorge M., Capretti F., Rasetti C., Svegliati Baroni G., Luzza F., Santori P, & Sciacqua A. (2022). The Apparent Asymmetrical Relationship Between Small Bowel Bacterial Overgrowth, Endotoxemia, and Liver Steatosis and Fibrosis in Cirrhotic and Non-Cirrhotic Patients: A Single-Center Pilot Study. Frontiers in Medicine, 9, 872428.

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Serum Endotoxin Analysis via LAL Assay

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Serum endotoxin was analysed using the QCL-1000 LAL endpoint assay (Lonza, Allendale, NJ, USA). The assay, and the values given by the manufacturer for intra-assay %CV (3.9 ± 0.46%) and inter-assay %CV (9.6 ± 0.75%), have been validated in our laboratory, as detailed previously [13 (link), 14 (link)].

Jackisch L., Kumsaiyai W., Moore J.D., Al-Daghri N., Kyrou I., Barber T.M., Randeva H., Kumar S., Tripathi G, & McTernan P.G. (2018). Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids. Diabetologia, 61(5), 1155-1166.

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