All participants underwent MRI scanning using a MAGNETOM Trio Tim 3.0 T system (Siemens Medical Solutions, Germany) equipped with a 32-channel head coil at the Shanxi Provincial People’s Hospital in Taiyuan. None of the participants, identified by two experienced radiologists as having significant brain abnormalities, was excluded from the study. During the scan, all participants were asked to relax with their eyes closed but to remain awake. Using 3D-FLASH sequence, a high-resolution T1-weighted MRI image was acquired with the parameters as follows: repetition time = 2,300 ms, echo time = 2.95 ms, FOV = 225 × 240 mm, matrix = 240 × 256 mm, flip angle = 9°, and voxel size = 0.9375 × 0.9375 × 1.2 mm3.
Magnetom trio tim 3.0 t system
Manufactured by Siemens
Sourced in Germany
The MAGNETOM Trio Tim 3.0 T system is a magnetic resonance imaging (MRI) scanner produced by Siemens. It operates at a field strength of 3.0 Tesla and utilizes the Tim (Total imaging matrix) technology for flexible and efficient image acquisition.
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6 protocols using magnetom trio tim 3.0 t system
1
High-Resolution T1-Weighted MRI Acquisition
2
Resting-State fMRI Acquisition Protocol
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MRI data were acquired from all the participants using a MAGNETOM Trio Tim 3.0 T system (Siemens Medical Solutions, Germany) at the Shanxi Provincial People’s Hospital, Taiyuan, People's Republic of China. Foam pads and earplugs were used to limit head motion and reduce scanner noise. Participants were positioned with their heads in a 32 channel head coil. All subjects were asked to rest quietly with their eyes closed, and confirmed that they did not sleep during the scan. We acquired 212 three-dimensional image volumes with the following parameters: TR=2,000 ms; TE=30 ms; section thickness=3 mm sagittal slices=32;FA=90º;FOV=240×240 mm2; and matrix=64×64 mm2.
3
Multimodal MRI Imaging Protocol
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Multimodal MRI was conducted using a Siemens Magnetom Trio, Tim 3.0 T system (http://www.siemensmriequipment.com ), using commercially available hardware and software. The following sequences were obtained: DWI (TR=3100 ms, TE=82 ms, b-value=1000 s/mm2, acquisition matrix=128×128, FOV=240 mm, section thickness=6.0 mm, section gap=1.2 mm, duration=48 s). Susceptibility-weighted imaging (SWI) (TR/TE/flip angle=27 ms/20 ms/15°, FOV=240 mm, acquisition matrix=384×32, section thickness=3.0 mm, duration=3.0 min 27 s). Three-dimensional (3D) time-of-flight (TOF) MR angiography (MRA; TR/TE/flip angle=20 ms/3.2 ms/18°, FOV=230 mm, acquisition matrix=256×256, section thickness=0.9 mm, duration=3.0 min 6.0 s) was performed.
All patients underwent MRI, including conventional T1WI, T2WI, diffusion-weighted imaging, and fluid-attenuated inversion recovery and SWI sequences.
All patients underwent MRI, including conventional T1WI, T2WI, diffusion-weighted imaging, and fluid-attenuated inversion recovery and SWI sequences.
4
Structural MRI Preprocessing Protocol
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Imaging data were collected from all subjects on a Siemens 3.0 T Magnetom Tim Trio system using a 32-channel head coil receiver. An anatomical T1-weighted MP-RAGE (magnetization prepared rapid acquisition gradient echo) was acquired for accurate segmentation and registration into standard space using the following parameters: TR = 1760 ms, TE = 2.2 ms, time of inversion (TI) = 900 ms, voxel size = 1 mm isotropic, field of view (FOV) = 256 × 256 mm, flip angle = 9°, receiver bandwidth = 200 Hz/pixel. Subject-specific grey-matter (GM), white-matter (WM) and cerebrospinal fluid (CSF) maps were generated for each subject using 3D automatic segmentation (FAST) (Zhang et al. 2001 ). The T1 and tissue maps were then spatially resampled onto the Montreal Neurological Institute (MNI) standard template (2-mm isotropic) using affine (12 DOF) (Jenkinson et al. 2002 (link)), and non-linear warp-fields (FNIRT; Andersson et al. 2007 ).
5
T1-weighted MRI Acquisition Protocol
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A T1-weighted MPRAGE sequence was acquired for each participant using a Siemens 3.0T Magnetom Tim Trio System with a 12-channel head receive coil (matrix 1 × 1 × 1 mm voxel, TR = 2500 ms, TE = 3.45 ms, FOV = 265 mm, inversion time = 1100, flip angle = 7 degrees). Image quality was visually inspected immediately after each structural acquisition to control for motion effects and other artifacts.
6
High-Resolution 3T MRI Brain Imaging
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All imaging data was acquired on a Siemens 3.0T Magnetom Tim Trio system using a 32-channel receiver head coil. A whole brain high resolution T1-weighted magnetization prepared rapid acquisition gradient echo (MP-RAGE) image was acquired for segmentation and registration purposes with the following parameters: TR = 1760 ms, TE = 2.2 ms, time of inversion (TI) = 900 ms, voxel size = 1 mm isotropic, field of view (FOV) = 256 × 256 mm, flip angle = 9°, receiver bandwidth = 200 Hz/pixel and a total scan time of 7 min and 32 s. The 3D structural images were inspected by a practicing neurosurgeon (D.J.C.) to ensure that the anatomical image did not show any structural alterations. The anatomical scans were then brain extracted and segmented using FSL's automated 3D segmentation tool (FAST; Zhang et al., 2001 (link)) to create subject-specific grey-matter (GM), white-matter (WM) and cerebrospinal fluid (CSF) tissue maps.
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