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Solo mia

Manufactured by Eigenvector Research
Sourced in United States

The SOLO + MIA is a combined instrument that provides data acquisition and analysis capabilities. It is designed to capture and process data from various analytical techniques. The core function of the SOLO + MIA is to facilitate data collection and interpretation, but a detailed description of its intended use is not available.

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Lab products found in correlation

5 protocols using solo mia

1

PCA Analysis of XRF Data

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The software SOLO + MIA (release 9.0) from Eigenvector Research Inc. (Manson, WA, USA) was used to perform Principal Component Analysis. This exploratory tool was used to extract information from the elemental semi-quantitative data provided by the in-built factory calibrations of the XRF instrument. Concentration data were preprocessed by autoscaling, that is, mean-centered and divided by standard deviation.
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2

Spectral Data Processing and Analysis

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SOLO + MIA (version 9.2.1.0, Eigenvector Research, Inc., Manson, WA, USA) was used for data processing and analysis.
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3

Multivariate Analysis of Cannabinoid Profiles

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For multivariate analysis, missing values were replaced with the method detection limit (MDL) divided by 2 for each assigned cannabinoid. In the cannabinoid profiles, where the MDL has not been determined for unassigned peaks, the missing data was replaced with half of the MDL of THC. Pearson correlation coefficients to determine relationships between metabolites were calculated using the cor script in R. As the concentration of a given metabolite does not necessarily correlate with pharmacological activity, the data were autoscaled by mean centering and scaling to unit variance in order to give each metabolite equal weight prior to multivariate analyses. Principal component analysis (PCA) and multiple linear regression (MLR) analysis were subsequently modeled using Solo + MIA (Eigenvector Research).
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4

Raman Spectral PCA Analysis

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PCA was performed with a commercial multivariate analysis package (Solo+MIA, Eigenvector Research, Inc). The intensity-scaled Raman spectra were mean-centered before performing PCA.
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5

Multivariate Analysis of Phytochemicals

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The flavonol and phenolic acid contents were determined with external calibration using Microsoft Excel (Microsoft, Redmond WA, USA). The mean of each sample was converted to wet weight from the loss on drying data from the freeze drier. Data was imported into Solo+MIA (Eigenvector Research Inc., Manson, WA, USA). The data were preprocessed using autoscaling prior to multivariate statistical analysis. Principal component analysis (PCA) was applied to the datasets and score plots were generated for the entire data set to visualize proximity in all cases. Analysis of variance-PCA (ANOVA-PCA) was utilized to determine whether any of the factors identified had an impact on the dataset (Harrington et al., 2005 ). The variations in the contents between different locations were evaluated using Kruskal-Wallis one-way analysis of variance and Tukey-Kramer method for unequal sample sizes. These statistical tests were performed using Microsoft Excel 2011.
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