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Signa 750

Manufactured by Siemens
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The SIGNA 750 is a medical imaging device produced by Siemens. It is a high-performance magnetic resonance imaging (MRI) system designed for advanced diagnostic imaging applications. The SIGNA 750 provides a range of advanced imaging capabilities, including high-resolution imaging, specialized imaging techniques, and efficient workflow integration.

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Lab products found in correlation

Magnetom trio, by Siemens (3 mentions) Signa 750, by GE Healthcare (2 mentions)

3 protocols using signa 750

1

Structural MRI Acquisition Protocol

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T1-weighted 3.0 T MR scans were acquired on GE SIGNA 750 (UW-Madison) and Siemens Magnetom Trio (UP-Medical Center) MR scanners to provide structural information for intermodality registration, spatial normalization, and brain region definition. The SIGNA 750 acquired MR data using a high resolution volumetric spoiled gradient (TI/TE/TR = 450/3.2/8.2ms, flip angle = 12°, slice thickness = 1mm no gap, FOV=256, matrix size = 256×256), while the Magnetom Trio scanner acquired MR data using a MPRAGE sequence (TI/TE/TR = 900/2.98/2300ms, flip angle = 9°, slice thickness = 1.2 mm, FOV = 240×256 mm, matrsix size = 160×240×256).
Lao P., Betthauser T., Hillmer A., Price J., Klunk W., Mihaila I., Higgins A., Bulova P., Hartley S., Hardison R., Tumuluru R., Murali D., Mathis C., Cohen A., Barnhart T., Devenny D., Mailick M., Johnson S., Handen B, & Christian B. (2015). The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by [11C]PiB. Alzheimer's & dementia : the journal of the Alzheimer's Association, 12(4), 380-390.
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2

Multimodal MRI Acquisition and Preprocessing

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T1 weighted 3.0 T MRI scans were acquired on a GE SIGNA 750 (UW-Madison) or a Siemens Magnetom Trio (UPMC). The SIGNA 750 acquired data using a high resolution volumetric spoiled gradient sequence (TI/TE/TR = 450/3.2/8.2 ms, flip angle = 12°, slice thickness = 1 mm no gap, matrix size = 256x256x156). The Magnetom Trio acquired data using a magnetization prepared rapid acquisition gradient echo sequence (MPRAGE; TI/TE/TR = 900/2.98/2300 ms, flip angle = 9°, slice thickness = 1.2 mm, matrix size = 160x240x256). In the 68 available baseline T1 MRI images, 8 (12%) were flagged at UPMC during preprocessing as containing “severe motion” or “significant motion”, leaving 60 T1 MRIs suitable for tissue type segmentation.
T2 weighted MRIs were also acquired on a 3.0 T GE SIGNA 750 (TE/TR = 85/9000 ms, slice thickness = 2 mm no gap, matrix size = 256x256x96) at UW-Madison. T2 weighted MRIs acquired at UPMC were not available for this analysis. Of the 40 available baseline T2 MRI images, 3 (7.5%) were flagged at UPMC during preprocessing as containing “severe motion” or “significant motion”, leaving 37 T2 MRIs suitable for tissue type segmentation.
Lao P.J., Handen B.L., Betthauser T.J., Cody K.A., Cohen A.D., Tudorascu D.L., Stone C.K., Price J.C., Johnson S.C., Klunk W.E, & Christian B.T. (2018). Imaging neurodegeneration in Down syndrome: brain templates for amyloid burden and tissue segmentation. Brain Imaging and Behavior, 13(2), 345-353.
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3

Multimodal MRI Acquisition and Quality Control

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T1 weighted 3.0 T MRI scans were acquired on a GE SIGNA 750 (UW-Madison) or a Siemens Magnetom Trio (UPMC). The SIGNA 750 acquired data using a high resolution volumetric spoiled gradient sequence (TI/TE/TR = 450/3.2/8.2 ms, flip angle = 12°, slice thickness = 1 mm no gap, matrix size = 256×256×156). The Magnetom Trio acquired data using a magnetization prepared rapid acquisition gradient echo sequence (MPRAGE; TI/TE/TR = 900/2.98/2300 ms, flip angle = 9°, slice thickness = 1.2 mm, matrix size = 160×240×256). In the 68 available baseline T1 MRI images, 8 (12%) were flagged at UPMC during preprocessing as containing “severe motion” or “significant motion”, leaving 60 T1 MRIs suitable for tissue type segmentation.
T2 weighted MRIs were also acquired on a 3.0 T GE SIGNA 750 (TE/TR= 85/9000 ms, slice thickness = 2 mm no gap, matrix size = 256×256×96) at UW-Madison. T2 weighted MRIs acquired at UPMC were not available for this analysis. Of the 40 available baseline T2 MRI images, 3 (7.5%) were flagged at UPMC during preprocessing as containing “severe motion” or “significant motion”, leaving 37 T2 MRIs suitable for tissue type segmentation.
Lao P.J., Handen B.L., Betthauser T.J., Cody K.A., Cohen A.D., Tudorascu D.L., Stone C.K., Price J.C., Johnson S.C., Klunk W.E, & Christian B.T. (2018). Imaging neurodegeneration in Down syndrome: brain templates for amyloid burden and tissue segmentation. Brain Imaging and Behavior, 13(2), 345-353.
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