Discovery 690 standard scanner

FDG-PET/CT was performed using a Discovery MI scanner (GE Healthcare, Waukesha, WI), Discovery 690 Standard scanner (GE Healthcare), Discovery VCT scanner (GE Healthcare), or Discovery ST scanner (GE Healthcare). FDG-PET/MR was performed using a 3 T PET/MR scanner (Signa PET/MR, GE Healthcare). According to our institution’s protocol, a standardized dose of 3.5 MBq of [¹⁸F]FDG per kg body weight (PET/CT) or 3.0 MBq per kg body weight (PET/MR) was injected until 2017, and from 2017 on, BMI-adapted body weight–dependent dosage protocols were used^{24 (link)}. The CT included of a standardized protocol of high-resolution axial volume acquisition (0.6–1.0 mm) with reconstructions in the coronal and sagittal plane in the bone and soft tissue kernel with contrast enhancement of the sinonasal and neck region. For the sinonasal and neck MR, dedicated regionalized T2-weighted and T1-weighted pulse sequences with and without gadolinium-based contrast agent and with and without fat suppression were used^{23 (link)}.

PSMA-PET/CT was performed using a Discovery MI scanner (GE Healthcare, Waukesha, WI), Discovery 690 Standard scanner (GE Healthcare), Discovery VCT scanner (GE Healthcare), Discovery ST scanner (GE Healthcare), or Siemens Biograph mCT Flow (Siemens Healthineers, Munich, Germany). The injected dose was 3–4 MBq/kg for [¹⁸F]F-PSMA-1007 and 2–3 MBq/kg for [⁶⁸Ga]Ga-PSMA-11 at both centers. The maximum injected dose was not more than 350 MBq. The uptake time was 60 min for [⁶⁸Ga]Ga-PSMA-11 and 90 min for [¹⁸F]F-PSMA-1007 at both centers.