Z vad fmk

Manufactured by Meilun

Z-VAD-FMK is a lab equipment product. It is a pan-caspase inhibitor that blocks apoptosis, or programmed cell death, by inhibiting the activity of caspase enzymes.

Automatically generated - may contain errors

Lab products found in correlation

Rapamycin, by Selleck Chemicals (1 mentions) Chloroquine cq, by Selleck Chemicals (1 mentions) Sp600125, by Selleck Chemicals (1 mentions) Sb203580, by Selleck Chemicals (1 mentions) 3 methyladenine 3 ma, by Selleck Chemicals (1 mentions) Sp600125, by Meilun (1 mentions) Daunorubicin, by Meilun (1 mentions) Doxorubicin, by Meilun (1 mentions) Sorafenib, by Meilun (1 mentions)

2 protocols using z vad fmk

Sunitinib and Inhibitor Compounds in Cell Study

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Sunitinib (purity≥98%) was purchased from Huateng pharmaceuticals-company (Hunan, China) and was dissolved in dimethyl sulfoxide (DMSO) (50 mM stock solution) and stored at −20°C and kept away from light. GA (purity≥97%) and NAC were supplied from Xiya Reagent Co., Ltd. (Shandong, China) and Solarbio (Beijing, China), respectively. Z-VAD-FMK was purchased from Meilunbio. SP600125, SB203580, chloroquine (CQ), 3-methyl adenine (3-MA) and Rapamycin were purchase from Selleck Chemicals (Houston, United States).

Tang T.L., Yang Y., Guo L., Xia S., Zhang B, & Yan M. (2022). Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway. Frontiers in Pharmacology, 13, 1002142.

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Antibody and Chemical Reagents for Cell Signaling

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The antibodies including Anti-GAPDH, Anti-CASK, Caspase-7, Anti-LC3B, SQSTM1/p62, Beclin-1, Anti-JNK1+JNK2+JNK3, Anti-phospho-JNK, Anti-c-Jun, Anti-phospho-c-Jun, Anti-MRP3, Anti-ABCG2 were listed in Table S2. JNK inhibitor SP600125 (MB5595), 3-Methyladen (3-MA, MB5063), Z-VAD-FMK (MB3313), sorafenib (MB1666), doxorubicin (MB1087), daunorubicin (MB1074), decitabine (5-Aza, MB1075), G418 (MB1733), puromycin (MB2005) were purchased from Dalian Meilun Biotechnology.

Ding B., Bao C., Jin L., Xu L., Fan W, & Lou W. (2021). CASK Silence Overcomes Sorafenib Resistance of Hepatocellular Carcinoma Through Activating Apoptosis and Autophagic Cell Death. Frontiers in Oncology, 11, 681683.

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