Nicolet continuum ft ir spectrometer

A Nicolet Continuum FT-IR Spectrometer from Thermo Scientific was used for Infrared spectroscopy in transmission mode. This instrument is equipped with a microscope for selection of sample area to be tested. DTGS KBr detector was used as well as a sample compartment of Right uScope. The FT-IR spectra was measured between 1000-4000 cm⁻¹, however for the purposes of this analysis specific regions where interactions of celecoxib and PVP are known to occur are presented[3 (link)]. These are near the carbonyl functional group (C=O), sulfoxide (SO₂) and the amine (NH₂) region. Changes in bandwidth of the carbonyl band was calculated at half of the band intensity for each sample.

A Nicolet Continuum FT-IR Spectrometer from Thermo Scientific was used for Infrared spectroscopy in transmission mode. This instrument is equipped with a microscope for selection of sample area to be tested. DTGS KBr detector was used as well as a sample compartment of Right uScope. The FT-IR spectra was measured between 1000-4000 cm⁻¹, however for the purposes of this analysis specific regions where interactions of celecoxib and PVP are known to occur are presented[3 (link)]. These are near the carbonyl functional group (C=O), sulfoxide (SO₂) and the amine (NH₂) region.